PPT ONLY WORDS
46 Questions
4 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What was the purpose of developing the 'get-away special' self-contained module?

  • To study the effects of sudden rocket acceleration on mouse lungs (correct)
  • To analyze the impact of space travel on the human body
  • To investigate the effects of microgravity on lung hemodynamics
  • To test the effects of space travel on human lungs

    • Which zone experienced absent perfusion in terms of lung hemodynamics?

  • Zone 3
  • Zone 1 (correct)
  • Zone 2
  • No zone experienced absent perfusion

    • What was the result of the mini-launch on the albumin level in the lavage fluid of the mice?

  • Normal Albumin level
  • Low Albumin level
  • No albumin detected
  • High Albumin level (correct)

    • How did the basic research on rocket acceleration inform clinical research for wounded veterans with SCI and/or TBI?

    <p>It led to the development of a Chest Optimization Protocol (COP)</p> Signup and view all the answers

    What was the hypothesis regarding the effects of acceleration on the mouse lungs?

    <p>Increased hemodynamic pressure in the basilar region of the lungs</p> Signup and view all the answers

    What was the purpose of building a mini-launch site near the UCF baseball stadium?

    <p>To study the effects of rocket acceleration on lung hemodynamics</p> Signup and view all the answers

    What was the result of the albumin analysis in the lavage fluid of the launched mice?

    <p>High albumin levels were detected</p> Signup and view all the answers

    How did basic research on rocket acceleration inform clinical research for wounded veterans with SCI and/or TBI?

    <p>It informed the Chest Optimization Protocol for wounded veterans</p> Signup and view all the answers

    What type of study is a case study (AKA case report)?

    <p>Observational study of a single patient's medical case</p> Signup and view all the answers

    What is the purpose of a case study in the medical field?

    <p>To learn about new monitoring methods, diagnostic procedures, and therapeutic interventions</p> Signup and view all the answers

    What is the role of an Institutional Review Board (IRB) in a case study?

    <p>To obtain approval for the invasive study</p> Signup and view all the answers

    What is the function of diaphragmatic pacing (DP) in the context of muscle fibers?

    <p>Changes fast twitch fibers back to slow twitch fibers</p> Signup and view all the answers

    What is the primary purpose of a case study in the medical field?

    <p>To present an unusual medical case to help medical teams learn about new monitoring or diagnostic methods</p> Signup and view all the answers

    What does a case series involve?

    <p>Presenting several similar case studies</p> Signup and view all the answers

    What type of muscle fibers are normally present in the diaphragm, and why are they important?

    <p>Slow twitch fibers, which are beneficial for ventilator-free breathing</p> Signup and view all the answers

    What is the role of Olfactory Mucosal Autograft (OMA) in the context of diaphragmatic pacing (DP)?

    <p>It consists of the patient's harvested olfactory ensheathing cells in a petri dish</p> Signup and view all the answers

    What statistical analysis method was used to compare differences between three or more groups during the research practicum?

    <p>ANOVA</p> Signup and view all the answers

    What was the impact on the research knowledge of students who transitioned to an online clinical research practicum due to the 2020 pandemic?

    <p>Their research knowledge remained the same</p> Signup and view all the answers

    What did the students use to collect data from ALS patients during the clinical part of the research practicum?

    <p>NM3 monitor</p> Signup and view all the answers

    What type of data analysis was conducted to determine whether significant changes had occurred in selected physiologic variables during the research practicum?

    <p>ANOVA</p> Signup and view all the answers

    What was the impact of transitioning to an online clinical research practicum on the research skills of students during the 2020 pandemic?

    <p>There was a significant decline in acquisition of research skills for students unable to attend a face-to-face clinical experience</p> Signup and view all the answers

    What did the HCC RT sophomores use to collect data from ALS patients during the clinical part of the research practicum?

    <p>NM3 monitor</p> Signup and view all the answers

    What was the statistical analysis method used to compare differences between three or more groups during the research practicum?

    <p>ANOVA Analysis</p> Signup and view all the answers

    What was the impact of on-site CRPs over a span of 3 consecutive years on the research knowledge and skills of HCC graduating sophomores?

    <p>Led to improvements in research knowledge and skills</p> Signup and view all the answers

    What does VCO2 (CO2 elimination) provide continuous feedback on?

    <p>Perfusion (heart) and ventilation (lungs)</p> Signup and view all the answers

    What physiologic alterations can affect VCO2?

    <p>Alveolar diffusion, ventilation, and circulation</p> Signup and view all the answers

    What is phase II of the volumetric capnogram on the NM3 screen?

    <p>Exhalation from transitional airways</p> Signup and view all the answers

    What do CO2 and flow integration provide estimates of on the NM3 screen?

    <p>Volumetric CO2 elimination and cardiac output</p> Signup and view all the answers

    What does VCO2 (CO2 elimination) provide continuous feedback on?

    <p>Ventilation (lungs) and perfusion (heart)</p> Signup and view all the answers

    What is Phase I of the volumetric capnogram on the NM3 screen?

    <p>CO₂ exhaled from conducting airways</p> Signup and view all the answers

    Which physiologic alterations will change the PaCO₂ reservoir?

    <p>Circulation, alveolar diffusion, ventilation</p> Signup and view all the answers

    What does the integration of CO2 and flow provide estimates of on the NM3 screen?

    <p>Volumetric CO2, static chest compliance, cardiac output</p> Signup and view all the answers

    What is the primary focus of transdisciplinary teams?

    <p>Improving patient care outcomes</p> Signup and view all the answers

    What was the main reason for the delayed time from baseline spirometry to subsequent spirometry for rural ALS patients?

    <p>Progressive physical impairments in patients</p> Signup and view all the answers

    What did the 2011 retrospective chart review reveal about rural ALS patients?

    <p>Increased average time from baseline spirometry to subsequent spirometry</p> Signup and view all the answers

    What was the initial step taken to address the lack of in-home PFT technology for rural ALS patients?

    <p>Looking for best available scientific evidence</p> Signup and view all the answers

    What was the $250,000.00 grant awarded for?

    <p>To determine the feasibility of RRTs performing various tests and delivering care</p> Signup and view all the answers

    What is the purpose of the Impulse Oscillometry (IOS) mentioned in the text?

    <p>To detect respiratory impairment in rural patients with ALS</p> Signup and view all the answers

    What was the role of RRTs in the development of iPADs mentioned in the text?

    <p>They assisted engineers in developing iPADs with respiratory therapy icons</p> Signup and view all the answers

    What was the primary focus of the $250,000.00 grant awarded from the Department of Defence (DoD)?

    <p>To determine the feasibility of RRTs performing various respiratory tests and delivering care</p> Signup and view all the answers

    What was the role of RRTs in the development of iPADs mentioned in the text?

    <p>Assisting in developing iPADs with RT icons</p> Signup and view all the answers

    What was found to be more accurate and less demanding on patients than spirometry in the text?

    <p>Impulse Oscillometry (IOS)</p> Signup and view all the answers

    What is the primary focus of transdisciplinary teams?

    <p>Improving patient care outcomes</p> Signup and view all the answers

    What was the main reason for the delayed time from baseline spirometry to subsequent spirometry for rural ALS patients?

    <p>Progressive physical impairments of patients</p> Signup and view all the answers

    What was the initial step taken to address the lack of in-home PFT technology for rural ALS patients?

    <p>Having RRTs design a PFT lab that can be taken to patients' homes</p> Signup and view all the answers

    How did the introduction of transdisciplinary teams impact the survival of ALS inpatients?

    <p>Significant improvement in survival</p> Signup and view all the answers

    Study Notes

    Get-Away Special Module and Research Insights

    • Developed to facilitate experiments in space, allowing scientists to gather data in microgravity environments.
    • Absent perfusion observed in the lung hemodynamics reflects areas significantly impacted by acceleration.
    • Mini-launch led to increased albumin levels in lavage fluid, indicating pulmonary effects from acceleration exposure.

    Impact of Rocket Acceleration Research

    • Basic research on rocket acceleration provided insights into lung dysfunction, informing clinical care for wounded veterans with spinal cord injuries (SCI) and traumatic brain injuries (TBI).
    • Hypothesis proposed that acceleration adversely affects mouse lung function, aiming to explore the biological mechanisms.

    Mini-Launch Site Purpose

    • Constructed near UCF baseball stadium to enhance accessibility for conducting experimental launches, serving educational and research purposes.

    Albumin Analysis Results

    • Elevated albumin levels found in lavage fluid of launched mice signal potential lung injury related to acceleration exposure.

    Case Study in Medical Research

    • Case studies are qualitative analyses focusing on individual patient experiences or outcomes.
    • Purpose is to explore unique clinical scenarios, contributing to understanding rare conditions or treatments without large sample sizes.
    • Institutional Review Board (IRB) oversees ethical approval, ensuring patient safety and confidentiality in case studies.

    Diaphragmatic Pacing and Muscle Fibers

    • Diaphragmatic pacing (DP) stimulates muscle fibers responsible for respiration, helping patients with impaired diaphragm function.
    • Diaphragm primarily composed of type I muscle fibers, crucial for endurance and sustained breathing.

    Role of Olfactory Mucosal Autograft (OMA)

    • OMA plays a supportive role in facilitating diaphragmatic function during DP, enhancing muscle recovery.

    Statistical Analysis Methods in Research

    • ANOVA utilized to compare differences across multiple groups, assessing treatment effects during research practicum.

    Online Clinical Research Practicum Outcomes

    • Transition to online formats due to the pandemic enhanced learning through technology, though may have limited hands-on experiences.
    • Students collected clinical data from ALS patients using remote methods, adapting to new research environments.

    VCO2 Monitoring and Physiological Feedback

    • VCO2 measures CO2 elimination, providing continuous feedback on respiratory performance and metabolic status.
    • Physiological changes, such as alterations in ventilation or metabolic processes, can impact VCO2 readings.

    Volumetric Capnogram Phases

    • Phase I reflects the initial exhalation phase, where dead space ventilation is indicated on the NM3 screen.
    • Phase II denotes the transitional phase of ventilation correlating with mixed gases in the lungs.

    Integration of CO2 and Flow

    • Combining CO2 with airflow data estimates ventilation efficiency and can indicate patient treatment needs.

    Transdisciplinary Teams and ALS Care

    • Focus on collaborative approaches to enhance patient care and address complex health issues.
    • Delays in spirometry for rural ALS patients attributed to access and technology limitations; initial steps focused on improving in-home pulmonary function testing (PFT).

    Funding and Technological Advancements

    • $250,000 grant from the Department of Defense aimed at developing technologies to improve patient monitoring and care for rural ALS patients.
    • Impulse Oscillometry (IOS) was found to be more patient-friendly and accurate compared to traditional spirometry for evaluating lung function.

    Impact of Transdisciplinary Teams on ALS Survival

    • Introduction of transdisciplinary teams significantly improved survival rates among ALS inpatients by fostering comprehensive care and treatment strategies.

    Studying That Suits You

    Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

    Quiz Team

    Description

    This quiz focuses on the study of the effects of sudden rocket acceleration on the epithelium and endothelium of mouse lungs in a 'get-away special' self-contained module placed aboard the shuttle's cargo bay. The quiz covers the hypothesis, including the hemodynamic pressure in the basilar region of mouse lungs and the potential outcomes such as pulmonary edema, decreased surfactant, and alveolar collapse.

    More Like This

    Use Quizgecko on...
    Browser
    Open
    Browser
    Browser