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Effects of Acetylcholine Nicotinic Receptor Antagonist on Myoneural Junction in Frog Lab 4 Physiology

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Effects of Acetylcholine Nicotinic Receptor Antagonist on Myoneural Junction in Frog Lab 4 Physiology

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Questions and Answers

Which ions are allowed to move across the channel when an agonist binds to Nicotinic AChRs?

Calcium and magnesium

Sodium and potassium (correct)

Phosphate and sulfate

Chloride and bicarbonate

Which type of ion channels are nicotinic acetylcholine receptors (nAChRs)?

Leakage ion channels

Voltage-gated ion channels

Mechanically gated ion channels

Ligand-gated ion channels (correct)

What is the effect of nicotine on nicotinic acetylcholine receptors (nAChRs)?

Inhibition

Neutralization

Stimulation (correct)

Amplification

What substance blocks nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction?

Curare Signup and view all the answers

What is the main function of nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction?

Initiating muscular contraction Signup and view all the answers

Which of the following tissues does NOT contain nicotinic acetylcholine receptors (nAChRs)?

Cardiac muscle tissue Signup and view all the answers

What is the mechanism of action of atracurium at the neuromuscular junction?

Acts as a competitive acetylcholine antagonist on neuromuscular junctions Signup and view all the answers

What is the role of acetylcholine at the neuromuscular junction?

Causing rapid depolarization of the muscle cell membrane Signup and view all the answers

What does the procedure involving injecting atracurium aim to achieve?

Observe the effect of atracurium on muscle contraction Signup and view all the answers

What is the purpose of stimulating the sciatic nerve after injecting atracurium?

To observe the contraction response of the gastrocnemius muscle Signup and view all the answers

Why is double pithing performed on the frog animal for this experiment?

To euthanize and immobilize the frog Signup and view all the answers

What is the purpose of tightening the upper part of the thigh for one leg?

To enable observation of differential muscle responses Signup and view all the answers