Effects of Acetylcholine Nicotinic Receptor Antagonist on Myoneural Junction in Frog Lab 4 Physiology
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Questions and Answers

Which ions are allowed to move across the channel when an agonist binds to Nicotinic AChRs?

  • Calcium and magnesium
  • Sodium and potassium (correct)
  • Phosphate and sulfate
  • Chloride and bicarbonate

Which type of ion channels are nicotinic acetylcholine receptors (nAChRs)?

  • Leakage ion channels
  • Voltage-gated ion channels
  • Mechanically gated ion channels
  • Ligand-gated ion channels (correct)

What is the effect of nicotine on nicotinic acetylcholine receptors (nAChRs)?

  • Inhibition
  • Neutralization
  • Stimulation (correct)
  • Amplification

What substance blocks nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction?

<p>Curare (C)</p> Signup and view all the answers

What is the main function of nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction?

<p>Initiating muscular contraction (D)</p> Signup and view all the answers

Which of the following tissues does NOT contain nicotinic acetylcholine receptors (nAChRs)?

<p>Cardiac muscle tissue (B)</p> Signup and view all the answers

What is the mechanism of action of atracurium at the neuromuscular junction?

<p>Acts as a competitive acetylcholine antagonist on neuromuscular junctions (A)</p> Signup and view all the answers

What is the role of acetylcholine at the neuromuscular junction?

<p>Causing rapid depolarization of the muscle cell membrane (B)</p> Signup and view all the answers

What does the procedure involving injecting atracurium aim to achieve?

<p>Observe the effect of atracurium on muscle contraction (B)</p> Signup and view all the answers

What is the purpose of stimulating the sciatic nerve after injecting atracurium?

<p>To observe the contraction response of the gastrocnemius muscle (C)</p> Signup and view all the answers

Why is double pithing performed on the frog animal for this experiment?

<p>To euthanize and immobilize the frog (D)</p> Signup and view all the answers

What is the purpose of tightening the upper part of the thigh for one leg?

<p>To enable observation of differential muscle responses (B)</p> Signup and view all the answers

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