Ecchymosis: Hematomas and Bruises
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Ecchymosis: Hematomas and Bruises

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Questions and Answers

What is the typical area size of an ecchymosis?

  • Less than 1 cm
  • More than 5 cm
  • 2-5 cm
  • 1-2 cm (correct)
  • What happens to the erythrocytes in ecchymosis?

  • They are released back into the bloodstream
  • They are converted to bilirubin
  • They are destroyed by immune cells
  • They are phagocytosed and degraded (correct)
  • What is the color of hemoglobin in ecchymosis?

  • Blue-green
  • Yellow
  • Golden-brown
  • Red-blue (correct)
  • What is the final product of bilirubin conversion in ecchymosis?

    <p>Hemosiderin</p> Signup and view all the answers

    What is the color of hemosiderin?

    <p>Golden-brown</p> Signup and view all the answers

    What type of cells are responsible for producing coagulation type materials?

    <p>Endothelial cells</p> Signup and view all the answers

    What is the function of anticoagulation mechanism in blood vessels?

    <p>To prevent blood clotting</p> Signup and view all the answers

    What is the role of collagen in blood vessels?

    <p>To provide structural support</p> Signup and view all the answers

    What is the result of injury to blood vessels?

    <p>Activation of blood clotting</p> Signup and view all the answers

    What is the function of endothelial cells in their normal state?

    <p>To prevent blood clotting</p> Signup and view all the answers

    What is the role of ECM in blood vessels?

    <p>To provide structural support</p> Signup and view all the answers

    What is the result of plasmin breaking down fibrin?

    <p>Production of fibrin split products</p> Signup and view all the answers

    What is a risk factor for atrial fibrillation?

    <p>Protein C and S deficiency</p> Signup and view all the answers

    What is the role of alpha 2 antiplasmin in the body?

    <p>To control the action of plasmin</p> Signup and view all the answers

    Which of the following is a primary cause of hypercoagulability?

    <p>Factor V mutations</p> Signup and view all the answers

    What is the effect of free plasmin on fibrin?

    <p>It breaks down the fibrin clot</p> Signup and view all the answers

    Why is it necessary to control the action of plasmin?

    <p>To prevent excessive bleeding</p> Signup and view all the answers

    What is a secondary cause of hypercoagulability?

    <p>Immobility</p> Signup and view all the answers

    What is the relationship between plasmin and alpha 2 antiplasmin?

    <p>Alpha 2 antiplasmin inactivates free plasmin</p> Signup and view all the answers

    What is the result of a combination of high risk factors and hypercoagulability?

    <p>Increased risk of thrombosis</p> Signup and view all the answers

    What is the role of protein C and S in the body?

    <p>To prevent thrombosis</p> Signup and view all the answers

    What is the result of Antithrombin III deficiency?

    <p>Increased thrombosis risk</p> Signup and view all the answers

    What is the common result of pooling of blood in veins?

    <p>Blood clot formation</p> Signup and view all the answers

    What can cause injury to vessels and lead to thrombosis?

    <p>Surgery, trauma, or burns</p> Signup and view all the answers

    What can increase the incidence of thrombosis?

    <p>Hypercoagulable conditions</p> Signup and view all the answers

    What can reduce the risk of deep venous thrombosis?

    <p>Regular exercise and movement</p> Signup and view all the answers

    What is a common risk factor for deep venous thrombosis?

    <p>Immobilization after surgery</p> Signup and view all the answers

    Study Notes

    Ecchymosis and Hematomas

    • Ecchymosis are subcutaneous hematomas or bruises that are 1-2 cm in area
    • Erythrocytes in these hemorrhages are phagocytosed and degraded
    • Hemoglobin is converted to bilirubin, which is blue-green in color, and eventually to hemosiderin, a golden-brown colored material

    Blood Vessels and Coagulation

    • Endothelial cells produce a variety of materials, including coagulation factors, inhibitors of blood coagulation, and vasodilation factors
    • Collagen and ECM play a role in coagulation
    • Antithrombin and fibrinolysis are involved in anticoagulation mechanisms
    • Endothelial cells have anti-thrombotic, anti-aggregation, and anti-coagulation effects

    Fibrinolysis and Plasmin

    • Plasmin breaks down fibrin, producing fibrin split products
    • Free plasmin is inactivated by alpha 2 antiplasmin to control its action

    Hypercoagulability

    • Primary causes of hypercoagulability include Factor V mutations, prothrombin mutations, Antithrombin III deficiency, and protein C and S deficiency
    • Secondary causes are considered high-risk, including individuals who are immobile or have a history of blood clots
    • Hypercoagulable conditions increase the incidence of thrombosis in situations that cause blood stasis, such as long flights or immobilization after surgery
    • Surgery, trauma, or burns may cause thrombosis due to injury to vessels, release of procoagulants, and reduced t-PA activity

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    Description

    Learn about ecchymosis, a type of subcutaneous hematoma or bruise, and its characteristics, including the breakdown of hemoglobin and the formation of bilirubin and hemosiderin.

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