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Questions and Answers

Which type of neuroglial cells act as macrophages and are responsible for searching for cellular debris to phagocytize?

  • Microglia (correct)
  • Astrocytes
  • Schwann cells
  • Ependymal cells

What is the primary composition of the myelin sheath?

  • 50% protein and 50% lipid
  • 20% protein and 80% lipid (correct)
  • 40% protein and 60% lipid
  • 30% protein and 70% lipid

In which part of the nervous system do oligodendrocytes form the myelin sheath?

  • Peripheral Nervous System (PNS)
  • Central Nervous System (CNS) (correct)
  • Both CNS and PNS
  • Neither CNS nor PNS

What condition involves the deterioration of oligodendrocytes and myelin sheaths in the CNS, leading to disrupted nerve conduction?

<p>Multiple sclerosis (A)</p> Signup and view all the answers

What are the Nodes of Ranvier?

<p>Gaps between segments of myelin sheath (B)</p> Signup and view all the answers

What does a resting membrane potential of approximately -70 mV indicate about a neuron?

<p>There are more negatively charged particles inside the membrane. (C)</p> Signup and view all the answers

Which factor does NOT contribute to the resting membrane potential?

<p>Increased permeability of all ions across the membrane. (A)</p> Signup and view all the answers

How do gated channels in the plasma membrane contribute to the generation of electrical currents?

<p>They can be opened or closed by specific stimuli. (C)</p> Signup and view all the answers

What primarily accounts for the difference in charge across a cell's plasma membrane at rest?

<p>The combined effect of ionic concentration gradients and selective permeability. (D)</p> Signup and view all the answers

What is an electrical current in the context of neurons?

<p>A movement of ions through gated channels. (C)</p> Signup and view all the answers

What occurs immediately after Na+ channels open?

<p>Na+ ions start to enter the cell (B)</p> Signup and view all the answers

During repolarization, what is happening to the K+ channels?

<p>K+ channels start closing after being fully open (D)</p> Signup and view all the answers

At resting membrane potential, which statement is true?

<p>Both Na+ and K+ channels are closed (D)</p> Signup and view all the answers

What happens at the peak of depolarization?

<p>Na+ channels close and K+ channels open (D)</p> Signup and view all the answers

Which phase follows the depolarization of a neuron?

<p>Repolarization begins (B)</p> Signup and view all the answers

What is the maximum density of Na+ channels found in the nodes of Ranvier?

<p>12,000 per μm2 (C)</p> Signup and view all the answers

What phenomenon describes the process where a nerve signal appears to jump from one node to another?

<p>Saltatory conduction (C)</p> Signup and view all the answers

What happens to the signal strength as it travels beneath the myelin sheath?

<p>It weakens (C)</p> Signup and view all the answers

Why does Na+ inflow at the node generate an action potential?

<p>Due to excitation of voltage-regulated gates (D)</p> Signup and view all the answers

What is a characteristic of the action potential generated at the node?

<p>It is non-decremental and strong (D)</p> Signup and view all the answers

What neurotransmitter is employed by cholinergic synapses?

<p>Acetylcholine (C)</p> Signup and view all the answers

What is the effect of acetylcholine on postsynaptic cells?

<p>It excites some postsynaptic cells. (C)</p> Signup and view all the answers

Which ion is primarily involved in the transmission at cholinergic synapses?

<p>Calcium (Ca2+) (D)</p> Signup and view all the answers

Which type of synapse is an excitatory adrenergic synapse?

<p>It uses norepinephrine as a neurotransmitter. (C)</p> Signup and view all the answers

What happens to the animation display in different operating systems during a presentation?

<p>Animations may not appear until in Presentation Mode. (A)</p> Signup and view all the answers

Where is the action potential primarily generated within a neuron?

<p>Trigger zone (B)</p> Signup and view all the answers

What is the minimum density of voltage-regulated gates required for an action potential to occur?

<p>350 to 500 gates per μm² (A)</p> Signup and view all the answers

What happens when an excitatory local potential reaches the trigger zone?

<p>It must still be strong enough to open gates. (C)</p> Signup and view all the answers

Which part of the neuron has the least density of voltage-regulated ion gates?

<p>Soma (C)</p> Signup and view all the answers

What is the role of ligand receptors in relation to action potentials?

<p>They may initiate excitatory local potentials. (A)</p> Signup and view all the answers

What happens to the plasma membrane during an action potential?

<p>It depolarizes and repolarizes rapidly. (C)</p> Signup and view all the answers

What is the effect of the density of voltage-regulated gates in the soma?

<p>It prevents action potentials from being initiated in the soma. (D)</p> Signup and view all the answers

What must occur for an action potential to be triggered at the trigger zone?

<p>The local potential must arrive with adequate strength. (C)</p> Signup and view all the answers

Flashcards

Microglia function

Microglia are neuroglial cells that act as immune cells, cleaning up cellular debris.

Myelin sheath function

Myelin is an insulating layer around nerve fibers, formed by glial cells, speeding up nerve impulse conduction.

Nodes of Ranvier

Gaps in the myelin sheath along an axon.

Multiple Sclerosis cause

A degenerative disorder where the myelin sheath in the CNS deteriorates, replacing it with scar tissue. This disrupts nerve conduction.

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Oligodendrocytes in CNS

Glial cells in the central nervous system (CNS) that form myelin.

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Ependymal cells

Cells that line the central canal of the spinal cord and the ventricles of the brain; they play a role in cerebrospinal fluid production and circulation.

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Resting membrane potential (RMP)

The voltage difference across a neuron's cell membrane when it's not transmitting signals; approximately -70mV.

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Electrical potential

Difference in charge between two points.

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Electrical current

Flow of charged particles (ions).

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Gated channels

Protein channels in the cell membrane that open or close in response to stimuli, controlling the flow of ions.

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Action Potential

A dramatic change in electrical potential across a plasma membrane, generated by voltage-regulated ion channels.

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Trigger Zone

Region of a neuron where action potentials are initiated due to high density of voltage-gated ion channels.

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Voltage-gated Ion Channels

Channels in a cell membrane that open or close in response to changes in membrane voltage.

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Local Potential

A temporary change in membrane potential that is localized and doesn't travel far down an axon.

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Soma

The cell body of a neuron; not enough voltage-gated channels to create an action potential.

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Plasma Membrane

The outer membrane of a cell, including the dendrite, that's the site of action potentials and ion channels.

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ECF

Extracellular fluid; the fluid outside a cell.

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ICF

Intracellular fluid; the fluid inside a cell.

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Saltatory Conduction

The rapid transmission of a nerve impulse along a myelinated axon, jumping from node to node along the axon.

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Nodes of Ranvier

Gaps in the myelin sheath along an axon where action potentials are generated.

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Myelin-covered regions

Areas of the axon wrapped in myelin, which insulates the axon and slows down the action potential.

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Fast Na+ diffusion

Rapid movement of sodium ions between the Nodes of Ranvier, crucial for the transmission of signals.

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Action Potential generation

Electrical signal initiated by rapid changes in ion permeability across the axon membrane, ultimately triggering the next signal at the next node.

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Resting Membrane Potential

The voltage difference across a neuron's membrane when it's not transmitting signals, typically around -70 mV.

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Depolarization

A change in membrane potential, where the inside of the cell becomes more positive.

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Repolarization

The return of the membrane potential to its resting state after depolarization.

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Sodium Channels

Channels in the neuron membrane that allow sodium ions (Na+) to pass through.

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Potassium Channels

Channels that allow potassium (K+) ions to pass through the neuron membrane.

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Cholinergic Synapse

A synapse that uses acetylcholine (ACh) as its neurotransmitter to communicate between neurons.

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Presynaptic Neuron

The neuron sending a signal across the synapse.

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Postsynaptic Neuron

The neuron receiving the signal across the synapse.

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Neurotransmitter

A chemical messenger that carries a signal across the synapse.

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Acetylcholine (ACh)

A neurotransmitter that excites some postsynaptic cells, particularly skeletal muscle.

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