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Questions and Answers
Which type of peripheral nerve disorder is characterized by affected nerves in a symmetric, length-dependent fashion?
Which type of peripheral nerve disorder is characterized by affected nerves in a symmetric, length-dependent fashion?
- Neuromuscular junction disorders
- Polyneuropathies (correct)
- Mononeuritis multiplex
- Peripheral nerve myopathies
What is a common initial presentation in patients with polyneuropathies?
What is a common initial presentation in patients with polyneuropathies?
- Fluctuating facial droop
- Visual disturbances
- Muscle weakness
- Loss of sensation and paresthesias (correct)
Which type of peripheral nerve disorder randomly affects individual nerves?
Which type of peripheral nerve disorder randomly affects individual nerves?
- Mononeuritis multiplex (correct)
- Polyneuropathies
- Stocking-and-glove syndrome
- Neuromuscular junction disorders
In which type of nerve disorder do patients commonly experience a 'stocking-and-glove' pattern of sensory loss?
In which type of nerve disorder do patients commonly experience a 'stocking-and-glove' pattern of sensory loss?
Which part of the longest nerves typically shows more pronounced axonal loss in polyneuropathies?
Which part of the longest nerves typically shows more pronounced axonal loss in polyneuropathies?
Which disorder is characterized by damage to multiple individual nerves, affecting them randomly?
Which disorder is characterized by damage to multiple individual nerves, affecting them randomly?
Which type of mutation is more common in Duchenne Muscular Dystrophy?
Which type of mutation is more common in Duchenne Muscular Dystrophy?
What is the main structural protein affected in Duchenne and Becker Muscular Dystrophy?
What is the main structural protein affected in Duchenne and Becker Muscular Dystrophy?
What is the typical outcome for most patients with Duchenne Muscular Dystrophy by the time they reach teenage years?
What is the typical outcome for most patients with Duchenne Muscular Dystrophy by the time they reach teenage years?
Where is the dystrophin gene located in individuals with Duchenne and Becker Muscular Dystrophy?
Where is the dystrophin gene located in individuals with Duchenne and Becker Muscular Dystrophy?
Which type of mutation is characteristic of Becker Muscular Dystrophy?
Which type of mutation is characteristic of Becker Muscular Dystrophy?
What autoimmune disorder is associated with increased expression of MHC class I molecules on myofibers and predominantly endomysial inflammatory infiltrates containing CD8+ cytotoxic T cells?
What autoimmune disorder is associated with increased expression of MHC class I molecules on myofibers and predominantly endomysial inflammatory infiltrates containing CD8+ cytotoxic T cells?
In a muscle biopsy of a patient with Duchenne Muscular Dystrophy, what is seen immunohistochemically?
In a muscle biopsy of a patient with Duchenne Muscular Dystrophy, what is seen immunohistochemically?
Which type of inflammatory myopathy is typically associated with skin manifestations?
Which type of inflammatory myopathy is typically associated with skin manifestations?
What disorder is characterized by an autoimmune attack leading to myofiber necrosis and subsequent regeneration?
What disorder is characterized by an autoimmune attack leading to myofiber necrosis and subsequent regeneration?
What is the most common autoimmune disorder characterized by increased expression of MHC class I molecules on myofibers?
What is the most common autoimmune disorder characterized by increased expression of MHC class I molecules on myofibers?
Which inflammatory myopathy is mainly associated with bilateral weakness and diminished reflexes?
Which inflammatory myopathy is mainly associated with bilateral weakness and diminished reflexes?
Which inflammatory myopathy is associated with increased risk of ovarian, gastric, and lymphoma malignancies?
Which inflammatory myopathy is associated with increased risk of ovarian, gastric, and lymphoma malignancies?
What autoimmune disease is characterized by fluctuating muscle weakness and targeting of the neuromuscular junction?
What autoimmune disease is characterized by fluctuating muscle weakness and targeting of the neuromuscular junction?
Which type of peripheral nerve damage is characterized by damage to Schwann cells or myelin with relative axonal sparing?
Which type of peripheral nerve damage is characterized by damage to Schwann cells or myelin with relative axonal sparing?
Which type of peripheral neuropathy is the most common form in diabetic patients?
Which type of peripheral neuropathy is the most common form in diabetic patients?
What is the main antigenic target in Myasthenia gravis?
What is the main antigenic target in Myasthenia gravis?
What type of peripheral nerve damage involves insults that directly injure the axon?
What type of peripheral nerve damage involves insults that directly injure the axon?
Which disorder is caused by autoantibodies inhibiting the function of presynaptic calcium channels?
Which disorder is caused by autoantibodies inhibiting the function of presynaptic calcium channels?
What is the characteristic pattern of attack seen in Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)?
What is the characteristic pattern of attack seen in Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)?
What is the main cause of peripheral neuropathy in diabetic patients?
What is the main cause of peripheral neuropathy in diabetic patients?
Which disorder is associated with thymic hyperplasia or thymoma?
Which disorder is associated with thymic hyperplasia or thymoma?
What is the characteristic feature of Duchenne and Becker Muscular Dystrophy from the given text?
What is the characteristic feature of Duchenne and Becker Muscular Dystrophy from the given text?
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