5 Questions
What is the definition of Dysfunctional Uterine Bleeding (DUB)?
DUB is defined as abnormal uterine bleeding in the absence of any organic lesion in the genital tract. It is a diagnosis of exclusion and one of the common causes of abnormal uterine bleeding.
How is DUB classified?
DUB is classified into primary DUB, which involves disturbance in the hypothalamopituitary-ovarian axis with no obvious cause or organic lesion, and secondary DUB, where a cause can be found but no organic lesion in the genital tract.
What are the types of DUB based on pathophysiology?
The types of DUB based on pathophysiology include ovulatory DUB, which involves corpus luteum insufficiency and persistent corpus luteum, and anovulatory DUB, which involves insufficient follicular development and persistent ovarian follicle.
What are the objectives of studying DUB according to Prof. Dr. Heera Tuladhar?
The objectives include defining DUB, classifying DUB, understanding the pathophysiology of ovulatory and anovulatory DUB, approaching a case of DUB through history taking, physical examination, and investigations, describing the medical management of DUB, and describing the surgical management of DUB (conservative Vs Radical).
What are the potential causes of secondary DUB?
The potential causes of secondary DUB include systemic disorders such as coagulopathy, thrombocytopenia, von Willebrand's disease, leukemia, hepatic disease, renal disease, hypothyroidism, as well as medications/iatrogenic factors like intrauterine contraceptive device, hormones (oral contraceptives, estrogen, progesterone, norplant, depo provera), and anticoagulant drugs.
Study Notes
Definition and Classification of Dysfunctional Uterine Bleeding (DUB)
- DUB is a condition characterized by abnormal uterine bleeding in the absence of any pelvic pathology or systemic disease.
Classification of DUB
- DUB is classified into two categories: ovulatory and anovulatory.
Types of DUB based on Pathophysiology
- Ovulatory DUB: characterized by regular ovulation, but abnormal bleeding due to hormone imbalance or abnormal prostaglandin production.
- Anovulatory DUB: characterized by irregular ovulation, leading to unopposed estrogen production and abnormal bleeding.
Objectives of Studying DUB
- According to Prof. Dr. Heera Tuladhar, the objectives of studying DUB are to understand the normal menstruation, to identify the causes of abnormal uterine bleeding, to diagnose and manage DUB effectively, and to prevent its complications.
Potential Causes of Secondary DUB
- Pregnancy-related complications such as miscarriage, ectopic pregnancy, and placenta previa.
- Uterine fibroids or polyps.
- Adenomyosis or endometrial hyperplasia.
- Infections such as endometritis or pelvic inflammatory disease.
- Hormonal imbalances or thyroid disorders.
- Use of certain medications, such as anticoagulants or hormone replacement therapy.
- Medical conditions, such as bleeding disorders or liver disease.
Test your knowledge of Dysfunctional Uterine Bleeding (DUB) with this quiz by Prof. Dr. Heera Tuladhar. MBBS, MD, FICS, HOD of the Department of Ob/Gyn at KIST Medical College. Explore the objectives, including defining and classifying DUB, understanding its pathophysiology, approaching a DUB case, and learning about medical and surgical management.
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