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Questions and Answers

What is the main geographical source of Calumba root?

  • Mozambique and East African countries (correct)
  • Asia
  • Northern Africa
  • Southern Africa
  • What type of root is Calumba?

  • Swollen adventitious root (correct)
  • Taproot
  • Fibrous root
  • Lateral root
  • What is a key characteristic of the taste of Calumba root?

  • Bitter (correct)
  • Sweet
  • Salty
  • Sour
  • Which layer forms the outer protective covering in the microscopical section of Calumba root?

    <p>Cork</p> Signup and view all the answers

    What is the typical diameter of Calumba root slices?

    <p>3-8 cm</p> Signup and view all the answers

    What type of starch granules are predominantly found in the powder of Calumba root?

    <p>Simple starch granules</p> Signup and view all the answers

    What color is the powder obtained from the Calumba root?

    <p>Yellowish-brown</p> Signup and view all the answers

    Which component is NOT part of the microscopical structure of Calumba root?

    <p>Epidermis</p> Signup and view all the answers

    Study Notes

    Calumba Root

    • Origin: Dried, transversely or obliquely sliced root of Jateorhiza palmata.
    • Family: Menispermaceae.
    • Geographic Sources: Indigenous to forests of Mozambique and East African countries.
    • Collection & Preparation: Rhizomes with roots are dug up during dry weather. Swollen fleshy roots are cut into transverse or oblique slices and dried in shade.
    • Macroscopic Characteristics:
      • Shape: Irregular, elliptical, or nearly circular with central depression on both sides.
      • Size: 3-8 cm in diameter and 6-12 mm thick.
      • Color: Greyish-brown.
      • Odor: Distinct.
      • Taste: Bitter.

    Microscopical Characters

    • Cork: Several layers of tabular, polygonal, thin-walled, brown cells.
    • Phelloderm: Parenchymatous cells containing starch granules; eccentric radiate or cleft hilum. Contains large isolated stone cells with unevenly thickened, pitted, and lignified yellow walls; contain 1-6 prisms of calcium oxalate.
    • Phloem: Parenchyma and radial bands of collapsed sieve tissue separated by wide medullary rays.
    • Xylem: Yellow, largely composed of parenchyma containing starch granules, radial rows of yellowish vessels, and reticulate or pitted thickened fibrous tracheids that often have pitted walls.

    Powder

    • Color: Yellowish-brown.
    • Odor: Slight.
    • Taste: Bitter.
    • Microscopic Features: Mostly simple starch granules; some compound with 2-3 components; hilum is eccentric cleft or stellate shaped. Large yellow sclereids that are unevenly thickened, yellow-pitted, lignified, and contain 1-6 calcium oxalate prisms. Fragments of cork cells. Fragments of large vessels with reticulately thickened or pitted yellow lignified walls.

    Active Constituents

    • 2-3% isoquinoline alkaloids (palmatine, calumbamine, and jateorhizine).
    • Colourless crystalline non-alkaloidal furano-diterpenes (calumbin, palmarin, isocalumbin, and jateorin).
    • Mucilage, starch, no tannin.

    Uses

    • Bitter tonic without astringency and stomachic.
    • Prescribed with iron salts.
    • Prescribed for anorexia and flatulent dyspepsia.
    • Stimulates taste buds, leading to saliva and digestive juice stimulation.

    Senega Root

    • Origin: Dried root and rootstock of Polygala senega.
    • Family: Polygalaceae.
    • Geographic Sources: Canada, USA, and Japan.
    • Macroscopical Characteristics:
      • Shape: Slender, greyish or brownish-yellow.
      • Apex: Crown of scaly leaves bearing stem bases.
      • Root Structure: Tapering, curved, and branching (dividing into 2 or more branches below the crown).
      • Odor: Methyl salicylate.
      • Taste: Initially sweet, then acrid.

    Active Constituents

    • Crude triterpenoidal saponins (senegin, 6-16%).
    • Methyl salicylate (volatile oil, 5%).
    • Sucrose and sterols.

    Tests for Identity

    • General Test: Powder boiled with water, solution strained, shaking resulting in persistent froth.
    • Confirmatory Test: Powder extracted with ether acidulated with dilute hydrochloric acid, ether removed, filtering, then ferric chloride solution added. Creates red-violet colour (salicylic acid).

    Uses

    • Stimulant expectorant for chronic bronchitis.
    • Often used with other expectorants (e.g., Ipecac, ammonium citrate, expectoral syrup).

    Krameria Root (Rhatany Root), Peruvian Rhatany

    • Origin: Dried roots of Krameria triandra.
    • Family: Leguminosae.
    • Geographic sources: Peru and Bolivia.
    • Macroscopical Characteristics: Large root with several long branches. Larger pieces are dark reddish-brown. Smaller pieces are typically brighter and smoother, with no visible transverse fissures. The bark has a strong astringent taste. The wood is tasteless.

    Active Constituents

    • Tannins: Phlobatannin or Krameria tannic acid (7-9%).
    • Colouring matter: Krameria-red (phlobaphene) –from oxidation of tannins.
    • Starch.
    • Calcium oxalate.
    • Benzofuran derivatives (rhataniphenols I and II).

    Uses

    • Astringent used as mouthwash.
    • Antimicrobial, useful in mouth and throat infections as a gargle.
    • Benzofuran compounds are effective UV filters and used in suntan preparations.

    Althaea, Marshmallow Root (Mucilagenous Root)

    • Origin: Dried root of Althaea officinalis.
    • Family: Malvaceae.
    • Geographic Sources: Wild-growing in England, Europe, and cultivated in France and Germany.
    • Macroscopical Characteristics: Root deprived of the brown corky layer and rootlets.

    Active Constituents

    • Tannins.
    • Phlobaphene.
    • Starch.
    • Calcium oxalate.
    • Benzofuran derivatives (rhataniphenols).

    Uses

    • Astringent; tincture used as mouthwash.
    • Antimicrobial; useful as a gargle for mouth and throat infections.
    • Benzofuran compounds act as effective UV-filters and are used in sun protection preparations.

    Sarsaparilla Root

    • Origin: Dried roots (and sometimes rhizomes) of Smilax ornata, from the Liliaceae family.
    • Geographic Sources: Central America, especially Costa Rica and Jamaica.
    • Macroscopical Characteristics: Imported in bundles of numerous slender roots, 3m long and 3mm thick; dark reddish-brown, shrunken and longitudinally furrowed; nearly odourless, with sweetish-acrid taste.

    Active Constituents

    • Steroidal saponins (related to cortisone and sex hormones)
    • Sarsapogenin, rhamnose and glucose (found during hydrolysis).
    • Similagenin (isomeric with sarsapogenin)
    • Omega-3 fatty acids.
    • Vitamin A and D.
    • Sarsapic acid.
    • Starch.
    • Sulfur.
    • Iron.
    • Calcium.
    • Potassium.
    • Copper.
    • Magnesium.

    Uses

    • General tonic & anabolic (increases protein accumulation).
    • Increases body weight, protein, and RNA in muscles and liver.
    • Stimulate bile production and digestive fluids, used in atonic dyspepsia, and for loss of appetite, indigestion, liver, and gallbladder problems.
    • Mild laxative for habitual constipation (inulin).
    • Effective diuretic, increasing urine flow.

    Dandelion Root (Taraxacum Root), Hepatic Stimulant Drug

    • Origin: Vertical rhizome and taproot of Taraxacum officinale.
    • Family: Compositae.
    • Geographic Sources: Europe and North America
    • Active Constituents:
      • 25-30% Inulin and other polysaccharides.
      • Sesquiterpene lactones (taraxacoside).
      • Triterpenes (taraxerol and alpha-amyrin).
      • Acids (caffeic, p-hydroxyphenyl).
      • Carotenoids (yellow coloring).
      • Volatile oils, tannins, potassium salts.

    Uses

    • Hepatic stimulant and tonic (traxacoside).
    • Stimulates bile secretion, reducing stone formation.
    • Restores liver function.
    • Increases secretion of digestive fluids and enzymes.
    • Bitter tonic for atonic dyspepsia; helps with loss of appetite, indigestion, liver and gallbladder problems.
    • Mild laxative (inulin).
    • Effective diuretic

    Ginseng Root

    • Origin: Dried roots of Panax ginseng (Asian ginseng) and Panax quinquefolius (American ginseng).
    • Family: Araliaceae
    • Geographic Sources: Eastern North America, and cultivated in China, Korea, and Japan.
    • Active Constituents:
      • Ginsenosides (triterpenoid saponins).
      • High molecular weight polysaccharides (glycans).
      • Polyacetylenic alcohols (panaxynol, panaxydol).
      • Sesquiterpenes (y-elemene).
      • Sterols, vitamins (D group), flavonoids, amino acids.
      • Sugars (glucose, fructose, sucrose).
      • Minerals (e.g., Zn, Cu, Mn, Ca).
      • Vitamins (e.g., B1, B2, B12).
      • Nicotinic acid, pantothenic acid, biotin.

    Uses

    • General tonic and anabolic; promotes protein accumulation (treatment of anemia).
    • Increases body weight, protein, and RNA in muscles and liver.
    • Adaptogenic; enhances physical and mental performance; and reduces fatigue.
    • Increases capacity for work.
    • Potential benefits for lowering cholesterol, improving immune function, treating diabetes, and enhancing sexual activity, among other functions.

    Echinacea (American Coneflower)

    • Origin: Dried roots and rhizomes of Echinacea angustifolia.
    • Family: Asteraceae.
    • Geographic Sources: Indigenous to America and Europe.
    • Active Constituents:
      • Caffeic acid glycosides (echinacoside).
      • Volatile oils (hydrocarbon 1,8 pentadecadiene).
      • Polyacetylenes.
      • Polysaccharides (echinacin B).

    Uses

    • Immunostimulant: boosts the body's infection-fighting ability.
    • Treatment of colds and respiratory tract infections.
    • Use topically as bacteriostatic, fungistatic, antiviral agent to heal wounds, burns, eczema, and psoriasis.
    • Anticancer and antiseptic for urinary tract infections.
    • Used in various preparations, including ointments, oral liquids, injections, lotions, and cosmetics

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