Drugs Used in Bladder Disorders
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Questions and Answers

What is the hallmark symptom of overactive bladder (OAB)?

  • Urinary frequency
  • Urinary incontinence
  • Nocturia
  • Urinary urgency (correct)

    • In the female body, why is the bladder smaller compared to males?

  • Because it is located anterior to the vagina
  • To match the smaller pelvic cavity in females
  • To accommodate the rectum position in females
  • Due to its positioning inferior to the uterus (correct)

    • What does urgency urinary incontinence (UUI) refer to?

  • Urinary leakage associated with urgency (correct)
  • Voiding 8 or more times in a 24-hour period
  • Urinary leakage during sleep
  • Sudden compelling desire to urinate

    • What defines urinary frequency?

    <p>Voiding 8 or more times in a 24-hour period</p> Signup and view all the answers

    Where is the bladder positioned in males?

    <p>Anterior to the rectum</p> Signup and view all the answers

    Which organization defines overactive bladder (OAB) as a syndrome?

    <p>International Continence Society (ICS)</p> Signup and view all the answers

    What is the hallmark symptom of overactive bladder (OAB)?

    <p>Urinary urgency</p> Signup and view all the answers

    Which type of cholinergic receptors in the bladder is responsible for parasympathetic detrusor contraction?

    <p>M3 only</p> Signup and view all the answers

    What is the main pharmacologic treatment of choice for overactive bladder (OAB)?

    <p>Antimuscarinic agents</p> Signup and view all the answers

    Which therapy for overactive bladder involves techniques like bladder training and biofeedback?

    <p>Behavioural therapy</p> Signup and view all the answers

    What are the major adverse effects that limit the use of antimuscarinic drugs in treating OAB?

    <p>Dry mouth and constipation</p> Signup and view all the answers

    Which type of receptors in the bladder are not responsible for cardiovascular effects?

    <p>Beta 3 receptors</p> Signup and view all the answers

    What is the primary mechanism of action of anticholinergics/antimuscarinics in treating bladder disorders?

    <p>Antagonism at muscarinic M3 receptors in the bladder detrusor muscle</p> Signup and view all the answers

    Which adverse effect is commonly associated with anticholinergic medication use?

    <p>Headache</p> Signup and view all the answers

    What category of adrenergic receptors are beta 3 receptors classified as?

    <p>Beta 3</p> Signup and view all the answers

    What is the role of beta 3 receptors in the bladder?

    <p>Present in the bladder wall</p> Signup and view all the answers

    What is the main indication for using duloxetine in bladder disorders?

    <p>Stress incontinence related to physical strain</p> Signup and view all the answers

    Which neurotransmitters does duloxetine primarily affect in its mechanism of action?

    <p>Serotonin and noradrenaline</p> Signup and view all the answers

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