18 Questions
What is the hallmark symptom of overactive bladder (OAB)?
Urinary urgency
In the female body, why is the bladder smaller compared to males?
Due to its positioning inferior to the uterus
What does urgency urinary incontinence (UUI) refer to?
Urinary leakage associated with urgency
What defines urinary frequency?
Voiding 8 or more times in a 24-hour period
Where is the bladder positioned in males?
Anterior to the rectum
Which organization defines overactive bladder (OAB) as a syndrome?
International Continence Society (ICS)
What is the hallmark symptom of overactive bladder (OAB)?
Urinary urgency
Which type of cholinergic receptors in the bladder is responsible for parasympathetic detrusor contraction?
M3 only
What is the main pharmacologic treatment of choice for overactive bladder (OAB)?
Antimuscarinic agents
Which therapy for overactive bladder involves techniques like bladder training and biofeedback?
Behavioural therapy
What are the major adverse effects that limit the use of antimuscarinic drugs in treating OAB?
Dry mouth and constipation
Which type of receptors in the bladder are not responsible for cardiovascular effects?
Beta 3 receptors
What is the primary mechanism of action of anticholinergics/antimuscarinics in treating bladder disorders?
Antagonism at muscarinic M3 receptors in the bladder detrusor muscle
Which adverse effect is commonly associated with anticholinergic medication use?
Headache
What category of adrenergic receptors are beta 3 receptors classified as?
Beta 3
What is the role of beta 3 receptors in the bladder?
Present in the bladder wall
What is the main indication for using duloxetine in bladder disorders?
Stress incontinence related to physical strain
Which neurotransmitters does duloxetine primarily affect in its mechanism of action?
Serotonin and noradrenaline
Learn about the anatomy of the bladder, a smooth muscular organ that stores urine in the human body. Understand the position and shape of the bladder, as well as its capacity and expansion. Gain insights into drugs used to treat bladder disorders.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
