Drugs Used in Bladder Disorders

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Questions and Answers

What is the hallmark symptom of overactive bladder (OAB)?

  • Urinary frequency
  • Urinary incontinence
  • Nocturia
  • Urinary urgency (correct)

In the female body, why is the bladder smaller compared to males?

  • Because it is located anterior to the vagina
  • To match the smaller pelvic cavity in females
  • To accommodate the rectum position in females
  • Due to its positioning inferior to the uterus (correct)

What does urgency urinary incontinence (UUI) refer to?

  • Urinary leakage associated with urgency (correct)
  • Voiding 8 or more times in a 24-hour period
  • Urinary leakage during sleep
  • Sudden compelling desire to urinate

What defines urinary frequency?

<p>Voiding 8 or more times in a 24-hour period (C)</p> Signup and view all the answers

Where is the bladder positioned in males?

<p>Anterior to the rectum (D)</p> Signup and view all the answers

Which organization defines overactive bladder (OAB) as a syndrome?

<p>International Continence Society (ICS) (B)</p> Signup and view all the answers

What is the hallmark symptom of overactive bladder (OAB)?

<p>Urinary urgency (D)</p> Signup and view all the answers

Which type of cholinergic receptors in the bladder is responsible for parasympathetic detrusor contraction?

<p>M3 only (D)</p> Signup and view all the answers

What is the main pharmacologic treatment of choice for overactive bladder (OAB)?

<p>Antimuscarinic agents (B)</p> Signup and view all the answers

Which therapy for overactive bladder involves techniques like bladder training and biofeedback?

<p>Behavioural therapy (D)</p> Signup and view all the answers

What are the major adverse effects that limit the use of antimuscarinic drugs in treating OAB?

<p>Dry mouth and constipation (C)</p> Signup and view all the answers

Which type of receptors in the bladder are not responsible for cardiovascular effects?

<p>Beta 3 receptors (A)</p> Signup and view all the answers

What is the primary mechanism of action of anticholinergics/antimuscarinics in treating bladder disorders?

<p>Antagonism at muscarinic M3 receptors in the bladder detrusor muscle (A)</p> Signup and view all the answers

Which adverse effect is commonly associated with anticholinergic medication use?

<p>Headache (B)</p> Signup and view all the answers

What category of adrenergic receptors are beta 3 receptors classified as?

<p>Beta 3 (D)</p> Signup and view all the answers

What is the role of beta 3 receptors in the bladder?

<p>Present in the bladder wall (C)</p> Signup and view all the answers

What is the main indication for using duloxetine in bladder disorders?

<p>Stress incontinence related to physical strain (A)</p> Signup and view all the answers

Which neurotransmitters does duloxetine primarily affect in its mechanism of action?

<p>Serotonin and noradrenaline (A)</p> Signup and view all the answers

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