16 Questions
Which drugs are part of the quadruple therapy for peptic ulcer disease and gastroesophageal reflux disease?
Bismuth subsalicylate, metronidazole, tetracycline, PPI
What is the action of H2 receptor antagonists in the stomach?
Inhibit basal, food-stimulated, nocturnal secretion of gastric acid
What are the therapeutic uses of H2 receptor antagonists?
Peptic ulcers
What are the adverse effects associated with H2 receptor antagonists?
Gynecomastia and galactorrhea
Which drugs belong to the class of Proton Pump Inhibitors?
Dexlansoprazole, omeprazole, esomeprazole, lansoprazole
What is the primary action of Proton Pump Inhibitors?
Inhibit the enzyme responsible for gastric acid secretion
Which enzyme system is irreversibly inhibited by omeprazole?
H+ -K+ -ATPase
What is the clinical use of misoprostol?
Prophylactic use in patients who take NSAIDs
Which of the following is an unwanted effect of sucralfate?
Constipation
What is the mechanism of action of bismuth subsalicylate?
Antimicrobial actions and inhibition of pepsin activity
What is a common side effect of antacids containing magnesium salts?
Diarrhea
What is the main therapeutic use of proton pump inhibitors (PPIs)?
Treatment of GORD
Which proton pump inhibitor inhibits CYP2C19?
Omeprazole
What is the mechanism of action of sodium bicarbonate?
Neutralizes acid
What is the action of sucralfate in the presence of acid?
Releases aluminium
What are the therapeutic uses of proton pump inhibitors (PPIs)?
Treatment of GORD, erosive esophagitis, and active duodenal ulcer
Test your knowledge on drugs used to treat peptic ulcer disease and gastroesophageal reflux disease. The quiz covers antimicrobial quadruple therapy, triple therapy, and H2 receptor antagonists, along with their actions and combinations.
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