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16 Questions

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Drugs for Peptic Ulcer and GERD

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Questions and Answers

Which drugs are part of the quadruple therapy for peptic ulcer disease and gastroesophageal reflux disease?

Dexlansoprazole, omeprazole, esomeprazole, pantoprazole

Cimetidine, famotidine, nizatidine, ranitidine

Amoxicillin, clarithromycin, PPI

Bismuth subsalicylate, metronidazole, tetracycline, PPI (correct)

What is the action of H2 receptor antagonists in the stomach?

Enhance the secretion of gastric acid

Inhibit basal, food-stimulated, nocturnal secretion of gastric acid (correct)

Eliminate the secretion of gastric acid completely

Increase the risk of gynecomastia and galactorrhea

What are the therapeutic uses of H2 receptor antagonists?

Diabetes

Arthritis

Hypertension

Peptic ulcers (correct)

What are the adverse effects associated with H2 receptor antagonists?

Gynecomastia and galactorrhea Signup and view all the answers

Which drugs belong to the class of Proton Pump Inhibitors?

Dexlansoprazole, omeprazole, esomeprazole, lansoprazole Signup and view all the answers

What is the primary action of Proton Pump Inhibitors?

Inhibit the enzyme responsible for gastric acid secretion Signup and view all the answers

Which enzyme system is irreversibly inhibited by omeprazole?

H+ -K+ -ATPase Signup and view all the answers

What is the clinical use of misoprostol?

Prophylactic use in patients who take NSAIDs Signup and view all the answers

Which of the following is an unwanted effect of sucralfate?

Constipation Signup and view all the answers

What is the mechanism of action of bismuth subsalicylate?

Antimicrobial actions and inhibition of pepsin activity Signup and view all the answers

What is a common side effect of antacids containing magnesium salts?

Diarrhea Signup and view all the answers

What is the main therapeutic use of proton pump inhibitors (PPIs)?

Treatment of GORD Signup and view all the answers

Which proton pump inhibitor inhibits CYP2C19?

Omeprazole Signup and view all the answers

What is the mechanism of action of sodium bicarbonate?

Neutralizes acid Signup and view all the answers

What is the action of sucralfate in the presence of acid?

Releases aluminium Signup and view all the answers

What are the therapeutic uses of proton pump inhibitors (PPIs)?

Treatment of GORD, erosive esophagitis, and active duodenal ulcer Signup and view all the answers