Podcast
Questions and Answers
What is the primary disorder in diabetes?
What is the primary disorder in diabetes?
- Lipid metabolism
- Insulin production
- Protein metabolism
- Carbohydrate metabolism (correct)
Which of the following symptoms results from a deficiency of insulin?
Which of the following symptoms results from a deficiency of insulin?
- Polyuria (correct)
- Weight loss
- Heart disease
- Neuropathy
What can sustained hyperglycemia lead to in the long term?
What can sustained hyperglycemia lead to in the long term?
- Neuropathy and stroke
- Polydipsia and ketonuria
- Amputations and impotence
- Renal failure and blindness (correct)
What percentage of all diabetes cases does type 1 diabetes account for?
What percentage of all diabetes cases does type 1 diabetes account for?
Why are terms like juvenile-onset diabetes mellitus falling out of favor?
Why are terms like juvenile-onset diabetes mellitus falling out of favor?
When does type 1 diabetes typically develop?
When does type 1 diabetes typically develop?
What is the primary defect in type 1 diabetes?
What is the primary defect in type 1 diabetes?
What is the main cause of symptoms in type 2 diabetes?
What is the main cause of symptoms in type 2 diabetes?
In type 2 diabetes, which tissues exhibit insulin resistance?
In type 2 diabetes, which tissues exhibit insulin resistance?
What factor leads to reduced binding of insulin to its receptors in insulin resistance?
What factor leads to reduced binding of insulin to its receptors in insulin resistance?
What hormone promotes hyperglycemia during pregnancy and increases threefold?
What hormone promotes hyperglycemia during pregnancy and increases threefold?
How is gestational diabetes defined?
How is gestational diabetes defined?
What is the current practice regarding oral medications for type 2 diabetes during pregnancy?
What is the current practice regarding oral medications for type 2 diabetes during pregnancy?
Which statement best describes the management of gestational diabetes?
Which statement best describes the management of gestational diabetes?
What effect does hyperinsulinism in the fetus have?
What effect does hyperinsulinism in the fetus have?
How should blood glucose levels be monitored during diabetic pregnancy according to some experts?
How should blood glucose levels be monitored during diabetic pregnancy according to some experts?
What is one of the criteria for diagnosing diabetes based on fasting plasma glucose levels?
What is one of the criteria for diagnosing diabetes based on fasting plasma glucose levels?
When is OGTT often used in diagnosing diabetes?
When is OGTT often used in diagnosing diabetes?
What level of 2-hour plasma glucose suggests diabetes during an OGTT?
What level of 2-hour plasma glucose suggests diabetes during an OGTT?
How is increased risk for diabetes (prediabetes) defined?
How is increased risk for diabetes (prediabetes) defined?
How can the risk for cardiovascular disease in individuals with prediabetes be reduced?
How can the risk for cardiovascular disease in individuals with prediabetes be reduced?
What is the primary goal of treating both type 1 and type 2 diabetes?
What is the primary goal of treating both type 1 and type 2 diabetes?
What is the current blood pressure goal set by the American Diabetes Association (ADA)?
What is the current blood pressure goal set by the American Diabetes Association (ADA)?
Which drug can reduce the risk for diabetic nephropathy in individuals with poor glycemic control?
Which drug can reduce the risk for diabetic nephropathy in individuals with poor glycemic control?
Which type of insulin is indicated for once-daily subQ dosing for both type 1 and type 2 diabetes?
Which type of insulin is indicated for once-daily subQ dosing for both type 1 and type 2 diabetes?
Which insulin analog is used to provide basal glycemic control and not given before meals to control postprandial hyperglycemia?
Which insulin analog is used to provide basal glycemic control and not given before meals to control postprandial hyperglycemia?
At what doses do the effects of insulin detemir persist for about 12 hours and up to 20 to 24 hours, respectively?
At what doses do the effects of insulin detemir persist for about 12 hours and up to 20 to 24 hours, respectively?
Which insulin product can be an option for individuals who do not realize a full 24 hours of effect with U-100 insulin glargine?
Which insulin product can be an option for individuals who do not realize a full 24 hours of effect with U-100 insulin glargine?
What is the primary difference between U-300 insulin glargine and U-100 insulin glargine in terms of concentration?
What is the primary difference between U-300 insulin glargine and U-100 insulin glargine in terms of concentration?
For which patients may twice-daily administration of U-100 insulin glargine be necessary?
For which patients may twice-daily administration of U-100 insulin glargine be necessary?
What distinguishes insulin degludec (Tresiba) from other human insulin analogs?
What distinguishes insulin degludec (Tresiba) from other human insulin analogs?
What is the primary function of insulin degludec?
What is the primary function of insulin degludec?
What is the recommended total daily insulin dosage range for patients?
What is the recommended total daily insulin dosage range for patients?
What strategy involves the use of both long-acting and short-acting insulins?
What strategy involves the use of both long-acting and short-acting insulins?
What is NOT a disadvantage of using premixed insulin products in a twice-daily regimen?
What is NOT a disadvantage of using premixed insulin products in a twice-daily regimen?
Why is tight glucose control challenging to achieve?
Why is tight glucose control challenging to achieve?
What occurs when insulin levels surpass the body's needs?
What occurs when insulin levels surpass the body's needs?
What should patients be educated on regarding insulin administration?
What should patients be educated on regarding insulin administration?
How does exercise impact insulin needs?
How does exercise impact insulin needs?
What is the primary therapeutic use of second-generation sulfonylureas?
What is the primary therapeutic use of second-generation sulfonylureas?
In what way do second-generation sulfonylureas differ significantly from first-generation agents?
In what way do second-generation sulfonylureas differ significantly from first-generation agents?
What is the main mechanism of action of metformin in lowering blood glucose levels?
What is the main mechanism of action of metformin in lowering blood glucose levels?
Which drug class can intensify hypoglycemia induced by insulin?
Which drug class can intensify hypoglycemia induced by insulin?
What is a common side effect associated with metformin use?
What is a common side effect associated with metformin use?
Which family of drugs promotes insulin release and is hence used only in type 2 diabetes?
Which family of drugs promotes insulin release and is hence used only in type 2 diabetes?
What is the primary complication that can arise from metformin use in patients with renal impairment?
What is the primary complication that can arise from metformin use in patients with renal impairment?
Which drug class leads to masking signs associated with sympathetic nervous system stimulation during hypoglycemia?
Which drug class leads to masking signs associated with sympathetic nervous system stimulation during hypoglycemia?
What is the primary difference between the indications for pramlintide and GLP-1 receptor agonists?
What is the primary difference between the indications for pramlintide and GLP-1 receptor agonists?
Which mechanism do both amylin and pramlintide utilize to reduce postprandial glucose levels?
Which mechanism do both amylin and pramlintide utilize to reduce postprandial glucose levels?
Why is hypoglycemia a principal concern with the use of pramlintide?
Why is hypoglycemia a principal concern with the use of pramlintide?
Which adverse effect is common to both exenatide (Byetta) and Exenatide Once Weekly (Bydureon)?
Which adverse effect is common to both exenatide (Byetta) and Exenatide Once Weekly (Bydureon)?
What is the main goal of utilizing incretin mimetics like exenatide in the treatment of diabetes?
What is the main goal of utilizing incretin mimetics like exenatide in the treatment of diabetes?
Why can hypoglycemia occur when exenatide is used in combination with a sulfonylurea?
Why can hypoglycemia occur when exenatide is used in combination with a sulfonylurea?
What is the mechanism of action of meglitinides, also known as glinides, in stimulating pancreatic insulin release?
What is the mechanism of action of meglitinides, also known as glinides, in stimulating pancreatic insulin release?
Which antidiabetic agent is contraindicated in patients with heart failure due to an associated risk?
Which antidiabetic agent is contraindicated in patients with heart failure due to an associated risk?
What is the primary therapeutic indication for thiazolidinediones (TZDs)?
What is the primary therapeutic indication for thiazolidinediones (TZDs)?
Which antidiabetic drug carries a low risk for hypoglycemia unless combined with insulin?
Which antidiabetic drug carries a low risk for hypoglycemia unless combined with insulin?
What is the main adverse effect associated with α-glucosidase inhibitors in the treatment of type 2 diabetes?
What is the main adverse effect associated with α-glucosidase inhibitors in the treatment of type 2 diabetes?
Which organ plays a significant role in glucose homeostasis by filtering and reabsorbing glucose in the renal tubules?
Which organ plays a significant role in glucose homeostasis by filtering and reabsorbing glucose in the renal tubules?
What is the mechanism of action of SGLT-2 inhibitors in improving glycemic control in patients with type 2 diabetes?
What is the mechanism of action of SGLT-2 inhibitors in improving glycemic control in patients with type 2 diabetes?
Which class of antidiabetic drugs is associated with an increased risk of genital fungal infections and UTIs as adverse effects?
Which class of antidiabetic drugs is associated with an increased risk of genital fungal infections and UTIs as adverse effects?
[Difficult] Which antidiabetic agent can cause ovulation in anovulatory premenopausal women?
[Difficult] Which antidiabetic agent can cause ovulation in anovulatory premenopausal women?
[Difficult] What is the main difference between glinides and sulfonylureas concerning their pharmacokinetic profile?
[Difficult] What is the main difference between glinides and sulfonylureas concerning their pharmacokinetic profile?
