Drugs and Nervous System Structure
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Questions and Answers

Which brain lobe is primarily responsible for processing visual information?

  • Parietal Lobe
  • Occipital Lobe (correct)
  • Temporal Lobe
  • Frontal Lobe
  • What is the primary function of the basal ganglia?

  • Emotional behavior and interpretation
  • Control of voluntary, smooth movement (correct)
  • Motor planning and learning
  • Memory consolidation and context
  • Which of the following is NOT a part of a neuron?

  • Myelin sheath (correct)
  • Dendrite
  • Axon hillock
  • Axon terminal
  • What is the principle of dynamic polarity in neurons?

    <p>Neurons can only transmit signals in one direction. (A)</p> Signup and view all the answers

    Which type of neuron carries information from the central nervous system to muscles and glands?

    <p>Motor neurons (A)</p> Signup and view all the answers

    What is the main function of the axon hillock?

    <p>Integrating input signals before transmitting them (A)</p> Signup and view all the answers

    What is the primary function of the limbic system?

    <p>Emotional behavior and interpretation (C)</p> Signup and view all the answers

    Which of the following best describes the function of sulci and gyri in the brain?

    <p>They increase the surface area of the brain (C)</p> Signup and view all the answers

    What is the name of the ion channel that plays a key role in the initial rising phase of an action potential?

    <p>Sodium (Na+) channel (D)</p> Signup and view all the answers

    What type of potential is generated when the extracellular side of the membrane becomes more positive due to an influx of chloride ions (Cl-)?

    <p>Hyperpolarization (A)</p> Signup and view all the answers

    Which of the following is NOT a key feature of an action potential?

    <p>It is a graded potential (B)</p> Signup and view all the answers

    Which phase of an action potential is characterized by the closing of sodium channels?

    <p>Repolarization phase (B)</p> Signup and view all the answers

    What is the main difference between the absolute and relative refractory periods?

    <p>The absolute refractory period is characterized by a complete inability to generate another action potential. (B)</p> Signup and view all the answers

    What is the term for the initial local depolarization of the membrane potential that triggers an action potential?

    <p>Threshold potential (B)</p> Signup and view all the answers

    Which type of ion channel is responsible for the efflux of potassium ions that contributes to hyperpolarization in the action potential?

    <p>Potassium (K+) channel (D)</p> Signup and view all the answers

    How does the frequency of action potentials relate to the strength of a stimulus?

    <p>Frequency is directly proportional to stimulus strength. (B)</p> Signup and view all the answers

    What is the primary reason for the resting membrane potential of a neuron being negative?

    <p>The presence of negatively charged proteins within the cell (D)</p> Signup and view all the answers

    What happens to the resting membrane potential when the permeability of the cell membrane to potassium ions increases?

    <p>The membrane potential becomes more negative (hyperpolarization) (C)</p> Signup and view all the answers

    Which of the following ions is most permeable across the neuronal membrane at rest?

    <p>Potassium (K+) (C)</p> Signup and view all the answers

    What is the approximate resting membrane potential of a neuron?

    <p>-70 mV (B)</p> Signup and view all the answers

    How is the resting membrane potential of a neuron measured?

    <p>By measuring the electrical potential inside the axon relative to the outside using a microelectrode (A)</p> Signup and view all the answers

    What is the primary difference between the electrical signal in a neuron and the chemical signal at a synapse?

    <p>The electrical signal is transmitted by ions, while the chemical signal is transmitted by neurotransmitters (A)</p> Signup and view all the answers

    What is the role of the axon hillock in neuronal signaling?

    <p>It integrates incoming signals and initiates action potentials (A)</p> Signup and view all the answers

    Which of the following mechanisms is NOT involved in the generation of the resting membrane potential?

    <p>The presence of positively charged proteins inside the cell (C)</p> Signup and view all the answers

    What is the primary function of the refractory period in neuronal signaling?

    <p>To ensure unidirectional propagation of action potentials. (B)</p> Signup and view all the answers

    Which of the following correctly describes the role of myelin in saltatory conduction?

    <p>Myelin concentrates current flow at the Nodes of Ranvier, increasing conduction speed. (A)</p> Signup and view all the answers

    What is the direct consequence of the release of a neurotransmitter from the presynaptic terminal?

    <p>Depolarization of the postsynaptic membrane. (B)</p> Signup and view all the answers

    Which of the following is NOT a step involved in the release of neurotransmitters at the synapse?

    <p>Opening of voltage-gated potassium channels in the presynaptic terminal. (D)</p> Signup and view all the answers

    What is the key difference between ionotropic and metabotropic receptors?

    <p>Ionotropic receptors directly control ion channel opening while metabotropic receptors indirectly influence ion channel activity through second messengers. (D)</p> Signup and view all the answers

    Which of the following accurately describes the characteristics of postsynaptic potentials (PSPs) compared to action potentials?

    <p>PSPs are conducted more slowly than action potentials. (C), PSPs are generated by passive mechanisms while action potentials are active. (D)</p> Signup and view all the answers

    Which of the following changes in a postsynaptic neuron is associated with an excitatory postsynaptic potential (EPSP)?

    <p>Depolarization of the membrane. (D)</p> Signup and view all the answers

    What is the primary function of autoreceptors in the synapse?

    <p>To provide feedback on the amount of neurotransmitter released. (C)</p> Signup and view all the answers

    What is a key characteristic of a psychoactive drug?

    <p>It significantly alters the functions of certain cells at low doses. (B)</p> Signup and view all the answers

    Which of the following is NOT a property of a successful nervous system?

    <p>Stimulation (B)</p> Signup and view all the answers

    What is the primary role of interneurons in the nervous system?

    <p>Integrating information between sensory and motor neurons. (A)</p> Signup and view all the answers

    What is the implication of Darwin's findings for animal research?

    <p>Animal models can provide valuable insights into human biology and behavior. (D)</p> Signup and view all the answers

    What type of neuron carries information towards the central nervous system?

    <p>Sensory neuron (D)</p> Signup and view all the answers

    What is the role of homeotic genes in the development of the nervous system?

    <p>Controlling the development of specific body parts. (D)</p> Signup and view all the answers

    Which of the following statements accurately describes the different types of neurons?

    <p>Sensory neurons receive information from the environment and motor neurons transmit information to muscles. (B)</p> Signup and view all the answers

    What is the function of muscle spindles in the nervous system?

    <p>To detect changes in muscle length. (A)</p> Signup and view all the answers

    Flashcards

    Cerebral Lobes

    Regions of the brain including occipital, parietal, frontal, and temporal lobes, each with distinct functions.

    Occipital Lobe

    Responsible for early-stage vision processing in the brain.

    Parietal Lobe

    Associated with somatosensation (touch and pain) and late-stage vision processing.

    Temporal Lobe

    Involved in memory, hearing, and language comprehension.

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    Frontal Lobe

    Associated with planning, movement signaling, working memory, and behavior inhibition.

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    Hippocampus

    Brain structure associated with memory consolidation and context.

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    Cerebellum

    Region of the brain involved in motor planning and learning.

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    Dynamic Polarity

    Principle stating that electrical signals in a neuron flow in one direction only.

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    Drug

    An exogenous chemical that alters cellular function.

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    Psychoactive drug

    Drugs that affect thinking, mood, or behavior.

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    Instrumental vs. Recreational drug use

    Instrumental use serves a purpose; recreational is for pleasure.

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    CNS organization

    How the central nervous system structures and coordinates bodily functions.

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    Four properties of a successful nervous system

    Reception, Transmission, Integration, Decision/Action.

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    Afferent neuron

    Sensory neuron that sends information toward the CNS.

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    Efferent neuron

    Motor neuron that sends information away from the CNS.

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    Interneuron

    Neuron that integrates information between sensory and motor neurons.

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    Resting Membrane Potential

    The electrical charge difference across a neuron's membrane, approximately -70 mV.

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    Presynaptic Transmission

    The process by which a presynaptic neuron sends signals to the postsynaptic neuron, involving electrical and chemical signals.

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    Microelectrode

    A tool inserted through the neuronal membrane to measure electrical potential inside the neuron.

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    Ion Distribution

    The unequal concentration of ions; Na+ and Cl- outside, K+ and A- inside a neuron.

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    Effects of Na+ Concentration

    Increasing extracellular Na+ concentration has no effect on resting potential.

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    Effects of K+ Concentration

    Increasing extracellular K+ concentration depolarizes the membrane potential.

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    Equilibrium Potential

    The membrane potential where ion flow is balanced; Na+ ~+55 mV, K+ ~-90 mV, Cl- ~-60 mV.

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    Selective Permeability

    The neuron's membrane allows K+ to move out while restricting other ions' movement.

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    Electrostatic Forces

    Forces that oppose diffusion and help maintain equilibrium.

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    Na+/K+ Pump

    A pump that moves 3 Na+ out and 2 K+ into a neuron using energy.

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    Graded Potentials

    Inputs received by a neuron from other neurons that can cause changes in membrane potential.

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    Hyperpolarization

    A change in membrane potential making it more negative, often due to K+ outflow.

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    Depolarization

    A process where the membrane potential becomes less negative due to Na+ influx.

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    Action Potential Features

    Characteristics of an action potential: nondecremental, proportional frequency, and all-or-none.

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    Phases of Action Potential

    Includes rising phase, repolarization phase, hyperpolarization phase, and afterhyperpolarization.

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    Refractory Periods

    The absolute refractory period prevents another AP; the relative makes it harder but possible.

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    Saltatory Conduction

    Rapid transmission of action potentials in myelinated axons between Nodes of Ranvier.

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    Nodes of Ranvier

    Gaps in the myelin sheath where action potentials are regenerated.

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    Action Potential

    Electrical signal transmitted along the axon of a neuron.

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    Neurotransmitter Release

    Process where neurotransmitters are released from vesicles into the synaptic cleft.

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    Excitatory Postsynaptic Potential (EPSP)

    Depolarizing potential that increases likelihood of a neuron firing.

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    Inhibitory Postsynaptic Potential (IPSP)

    Hyperpolarizing potential that decreases likelihood of a neuron firing.

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    Study Notes

    Lecture 1 - How We Study Drugs

    • Drugs are defined differently in various contexts.
    • A drug is an exogenous chemical not essential for normal cell function, altering cellular function at low doses.
    • Psychoactive drugs influence thoughts, mood, and behavior, categorized as instrumental or recreational depending on use.

    Lecture 2 - Nervous System Structure and Function

    • Darwin's research impacts animal studies. Animal models are used in studying the brain.
    • The theory of evolution provides insight into animal models, with advantages and disadvantages.
    • Homeotic genes control body development in various species, similar across species.
    • Four F's describe specific functions within a successful nervous system.
    • Reception, transduction, transmission, and integration are crucial components of a successful nervous system.
    • A simple sensorimotor circuit comprises five parts: neurons, muscle, receptor (e.g., muscle spindle), transmission (sensory and motor neurons), synapse.
    • Sensory neurons receive info, motor neurons transmit to muscles, and interneurons connect them.
    • Spinal cord integrates info between sensory and motor neurons.

    Brain Organization and Function: Mapping the Brain

    • Cerebral lobes (occipital, parietal, frontal, temporal) are associated with specific functions.
    • Occipital lobe: early-stage vision.
    • Parietal lobe: somatosensation (touch, pain) and late-stage vision.
    • Temporal lobe: memory, hearing, language comprehension.
    • Frontal lobe: planning, movement, working memory, and impulse control.
    • Specific brain areas (e.g., hippocampus, cerebellum, limbic system) are involved in various important functions.

    Lecture 3 - Neurons and Resting Potential

    • Neuron structure includes soma, axon hillock, axon, axon terminal, and dendrites.
    • Soma is the cell body, dendrites receive inputs, axon terminals release neurotransmitters.
    • The principle of dynamic polarity describes electrical signals flowing one way in a neuron.
    • Neurons are classified as sensory (afferent), motor (efferent), or interneurons.
    • Membrane potential, the difference in electrical charge, is -70 mV (resting potential).
    • Ions (Na+, Cl-, K+, A-) are distributed unevenly across the membrane.

    Lecture 4 - Action Potential

    • Action potentials are rapid, large changes in membrane potential.
    • All-or-none phenomenon, nondecremental, frequency directly related to stimulus intensity.
    • Action potentials have a rising, repolarization, and hyperpolarization phase.
    • These phases involve specific ion channels. Refractory periods prevent backward movement and limit firing rates.
    • Saltatory conduction speeds up signal transmission in myelinated axons. Saltatory conduction is possible due to the presence of Nodes of Ranvier.

    Lecture 5 - Synaptic Transmission

    • Synaptic transmission involves the release of neurotransmitters.
    • Neurotransmitters are released from presynaptic neurons.
    • Action potentials cause neurotransmitter release from presynaptic terminal to postsynaptic receptor.
    • Neurotransmitter receptors lead to opening/closing ion channels on postsynaptic membrane causing depolarization, hyperpolarization, or other effects.
    • Synaptic Transmission involves: Arrival, Release of neurotransmitter, receptor stimulation.
    • Two major classes of receptors: ionotropic, metabotropic.
    • Postsynaptic potentials (PSPs) are graded potentials (different sizes).
    • Excitatory (EPSP) and inhibitory postsynaptic potentials (IPSP).
    • Autoreceptors regulate neurotransmitter release.
    • Two major mechanisms for turning off neurotransmitters: reuptake and enzymatic degradation.

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    Description

    Explore the classification of drugs and their effects on behavior in this quiz, which touches on psychoactive substances and their uses. Additionally, learn about the structure and functions of the nervous system, including the impact of evolution on animal models and key processes like reception and integration.

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