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Questions and Answers
Which medication is known to cause Tardive Dyskinesia?
Which medication is known to cause Tardive Dyskinesia?
What syndrome is associated with Hydralazine?
What syndrome is associated with Hydralazine?
Which medication is primarily known for causing Red Man Syndrome?
Which medication is primarily known for causing Red Man Syndrome?
Which drug is associated with positive Coombs' test results?
Which drug is associated with positive Coombs' test results?
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What effect does Nitroglycerin tolerance have during weekends?
What effect does Nitroglycerin tolerance have during weekends?
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Which drug is known to cause agranulocytosis?
Which drug is known to cause agranulocytosis?
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Which of the following medications is associated with the risk of fatal hepatotoxicity?
Which of the following medications is associated with the risk of fatal hepatotoxicity?
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What is a common side effect of tricyclic antidepressants?
What is a common side effect of tricyclic antidepressants?
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Which drug can lead to cartilage damage in children?
Which drug can lead to cartilage damage in children?
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Which of the following drugs is known to cause gingival hyperplasia?
Which of the following drugs is known to cause gingival hyperplasia?
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Which medication is known to induce cytochrome P450 enzymes?
Which medication is known to induce cytochrome P450 enzymes?
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What is a potential side effect of quinidine?
What is a potential side effect of quinidine?
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What toxic effect is commonly associated with the use of lithium?
What toxic effect is commonly associated with the use of lithium?
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Study Notes
Drug Toxicities
- Agranulocytosis: Associated with clozapine, chloramphenicol
- Aplastic Anemia: Linked to NSAIDs, benzene
- Atropine-like Side Effects: Caused by tricyclic antidepressants
- Cardiotoxicity: Doxorubicin, daunorubicin are implicated
- Cartilage Damage in Children: Fluoroquinolones (ciprofloxacin and norfloxacin)
- Cinchonism: A result of quinidine
- Diabetes Insipidus: Lithium is a potential cause
- Disulfiram-like Effect: Metronidazole
- Extrapyramidal Side Effects: Antipsychotics (thioridazine, haloperidol, chlorpromazine)
- Fanconi's Syndrome: Tetracycline
- Fatal Hepatotoxicity (necrosis): Valproic Acid, Halothane, Acetaminophen, Phenytoin
- Gingical Hyperplasia: Chloramphenicol and cimetidine implicated
- Gray Baby Syndrome: Chloramphenicol
- Gynecomastia: Azoles, spironolactone, digitalis
- Hemolytic Anemia in G6PD-deficiency: Sulfonamides, isoniazid, aspirin
- Hepatitis: Ibuprofen, primaquine, isoniazid, niacin, tamoxifen, ca++ channel blockers
- Hot Flashes, Flushing: Ibuprofen, primaquine
- Induce CP450: Barbiturates, phenytoin, carbamazepine, rifampin
- Inhibit CP450: Cimetidine, ketoconazole
- Interstitial Nephritis: NSAIDs (except aspirin), furosemide, sulfonamides
- Monday Disease: Nitroglycerin (industrial exposure)
- Orange Body Fluids: Rifampin
- Osteoporosis: Heparin, corticosteroids, methyldopa, bleomycin, amiodarone, vancomycin
- Positive Coombs' Test: Methyldopa
- Pulmonary Fibrosis: Bleomycin, amiodarone
- Red Man Syndrome: Vancomycin
- Severe HTN with SLE-like Syndrome: MAOIs
- Tardive Dyskinesia: Antipsychotics (thioridazine, haloperidol, chlorpromazine), antipsychotics
- Tinnitus: Aspirin, quinidine
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Description
Explore the various toxic effects of different drugs in this quiz. Understand the associations between specific medications and their potential adverse reactions, from agranulocytosis linked to clozapine to fatal hepatotoxicity from acetaminophen. Test your knowledge of drug safety and side effects.
