Podcast
Questions and Answers
Which drug has a strong recommendation with high quality of evidence for the treatment of cholera?
Which drug has a strong recommendation with high quality of evidence for the treatment of cholera?
What is the treatment regimen recommended for adults with non-typhoidal Salmonella dysentery?
What is the treatment regimen recommended for adults with non-typhoidal Salmonella dysentery?
Which alternative antimicrobial may be used for amoebiasis in addition to metronidazole?
Which alternative antimicrobial may be used for amoebiasis in addition to metronidazole?
What is the recommended treatment for adults with Shigella dysentery once culture results are available?
What is the recommended treatment for adults with Shigella dysentery once culture results are available?
Signup and view all the answers
Which of the following drugs is recommended with low to moderate quality of evidence for cholera treatment?
Which of the following drugs is recommended with low to moderate quality of evidence for cholera treatment?
Signup and view all the answers
Which of the following drugs for cholera has the lowest quality of evidence?
Which of the following drugs for cholera has the lowest quality of evidence?
Signup and view all the answers
Which antimicrobial can be used in the treatment of amoebiasis as a monotherapy?
Which antimicrobial can be used in the treatment of amoebiasis as a monotherapy?
Signup and view all the answers
For which condition is ciprofloxacin recommended as both a monotherapy and an alternative drug?
For which condition is ciprofloxacin recommended as both a monotherapy and an alternative drug?
Signup and view all the answers
What is the recommended duration of treatment for adults with confirmed amoebiasis using metronidazole?
What is the recommended duration of treatment for adults with confirmed amoebiasis using metronidazole?
Signup and view all the answers
Which drug is NOT recommended for adults with suspected or confirmed cholera?
Which drug is NOT recommended for adults with suspected or confirmed cholera?
Signup and view all the answers
Which of the following antibiotics has a strong recommendation for treatment of Shigella dysentery based on moderate to high quality of evidence?
Which of the following antibiotics has a strong recommendation for treatment of Shigella dysentery based on moderate to high quality of evidence?
Signup and view all the answers
What is the primary reason for modifying antimicrobial therapy after culture results are available for non-typhoidal Salmonella infection?
What is the primary reason for modifying antimicrobial therapy after culture results are available for non-typhoidal Salmonella infection?
Signup and view all the answers
Which drug is recommended for treating cholera at a single 1 g dose but has a quality of evidence that is categorized differently than others in the same group?
Which drug is recommended for treating cholera at a single 1 g dose but has a quality of evidence that is categorized differently than others in the same group?
Signup and view all the answers
Which of the following is a second-line alternative for amoebiasis alongside metronidazole?
Which of the following is a second-line alternative for amoebiasis alongside metronidazole?
Signup and view all the answers
In the treatment of cholera, how many times a day is doxycycline recommended if used?
In the treatment of cholera, how many times a day is doxycycline recommended if used?
Signup and view all the answers
Study Notes
Cholera
- Recommended drugs for cholera include Azithromycin (1 g PO single dose), showing strong recommendation and high quality of evidence.
- Ciprofloxacin may be given as 1-2 g PO single dose or 500 mg twice a day for 3 days, with a strong recommendation but lower quality of evidence.
- Doxycycline (100 mg PO twice a day for 3 days) serves as an alternative treatment, also with a strong recommendation but low to moderate evidence quality.
Shigella Dysentery
- Treatment options for Shigella dysentery include Ceftriaxone (1 g IV once daily for 5 days) or Ciprofloxacin (500 mg PO twice a day for 5 days), both strongly recommended with moderate to high quality of evidence.
- Azithromycin (1 g PO single dose) is another recommended option for treatment.
- Antimicrobial therapy can be adjusted based on culture results once available.
Non-Typhoidal Salmonella
- Recommended treatments for non-typhoidal Salmonella dysentery include Ciprofloxacin (500 mg PO twice a day for 5 days) and Ceftriaxone (1 g IV once daily for 5 days), with strong recommendations and variable evidence quality.
- Adjustments to antimicrobial therapy can be made after culture results are obtained.
Amebiasis
- Confirmed amoebiasis is treated with Metronidazole (500-750 mg tablet three times a day for 10 days), receiving a strong recommendation and high quality of evidence.
- Alternative treatments include Tinidazole (2 g once a day for 3 days) and Secnidazole (2 g single dose), both strongly recommended with high evidence quality.
- Diloxanide furoate (500 mg three times a day) may be used alongside Metronidazole if accessible.
Cholera
- Recommended drugs for cholera include Azithromycin (1 g PO single dose), showing strong recommendation and high quality of evidence.
- Ciprofloxacin may be given as 1-2 g PO single dose or 500 mg twice a day for 3 days, with a strong recommendation but lower quality of evidence.
- Doxycycline (100 mg PO twice a day for 3 days) serves as an alternative treatment, also with a strong recommendation but low to moderate evidence quality.
Shigella Dysentery
- Treatment options for Shigella dysentery include Ceftriaxone (1 g IV once daily for 5 days) or Ciprofloxacin (500 mg PO twice a day for 5 days), both strongly recommended with moderate to high quality of evidence.
- Azithromycin (1 g PO single dose) is another recommended option for treatment.
- Antimicrobial therapy can be adjusted based on culture results once available.
Non-Typhoidal Salmonella
- Recommended treatments for non-typhoidal Salmonella dysentery include Ciprofloxacin (500 mg PO twice a day for 5 days) and Ceftriaxone (1 g IV once daily for 5 days), with strong recommendations and variable evidence quality.
- Adjustments to antimicrobial therapy can be made after culture results are obtained.
Amebiasis
- Confirmed amoebiasis is treated with Metronidazole (500-750 mg tablet three times a day for 10 days), receiving a strong recommendation and high quality of evidence.
- Alternative treatments include Tinidazole (2 g once a day for 3 days) and Secnidazole (2 g single dose), both strongly recommended with high evidence quality.
- Diloxanide furoate (500 mg three times a day) may be used alongside Metronidazole if accessible.
Cholera
- Recommended drugs for cholera include Azithromycin (1 g PO single dose), showing strong recommendation and high quality of evidence.
- Ciprofloxacin may be given as 1-2 g PO single dose or 500 mg twice a day for 3 days, with a strong recommendation but lower quality of evidence.
- Doxycycline (100 mg PO twice a day for 3 days) serves as an alternative treatment, also with a strong recommendation but low to moderate evidence quality.
Shigella Dysentery
- Treatment options for Shigella dysentery include Ceftriaxone (1 g IV once daily for 5 days) or Ciprofloxacin (500 mg PO twice a day for 5 days), both strongly recommended with moderate to high quality of evidence.
- Azithromycin (1 g PO single dose) is another recommended option for treatment.
- Antimicrobial therapy can be adjusted based on culture results once available.
Non-Typhoidal Salmonella
- Recommended treatments for non-typhoidal Salmonella dysentery include Ciprofloxacin (500 mg PO twice a day for 5 days) and Ceftriaxone (1 g IV once daily for 5 days), with strong recommendations and variable evidence quality.
- Adjustments to antimicrobial therapy can be made after culture results are obtained.
Amebiasis
- Confirmed amoebiasis is treated with Metronidazole (500-750 mg tablet three times a day for 10 days), receiving a strong recommendation and high quality of evidence.
- Alternative treatments include Tinidazole (2 g once a day for 3 days) and Secnidazole (2 g single dose), both strongly recommended with high evidence quality.
- Diloxanide furoate (500 mg three times a day) may be used alongside Metronidazole if accessible.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Description
This quiz covers recommended drug treatments for various infections, including cholera and Shigella. You'll learn about the specific medications, dosages, and the level of evidence supporting their use. Test your knowledge on effective treatments and improve your understanding of infectious disease management.
