Drug Metabolism Overview

Conjugation products have increased molecular weight and are more active, while Phase I reactions often produce inactive metabolites

Conjugation products have decreased molecular weight and are less active, while Phase I reactions often produce active metabolites

Conjugation products have increased molecular weight and are less active, while Phase I reactions often produce active metabolites (correct)

Conjugation products have decreased molecular weight and are more active, while Phase I reactions often produce inactive metabolites

Acetylation

Methylation

Glutathione conjugation (correct)

Sulphation

Methyltransferase

Glutathione S-transferases (correct)

Sulfotransferases

Glucuronosyltransferases

<p>XM-ligase</p> Signup and view all the answers

<p>Formation of glycine conjugate</p> Signup and view all the answers