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Questions and Answers
Which organ primarily plays an active role in enzymatic deactivation of drugs?
Which organ primarily plays an active role in enzymatic deactivation of drugs?
- Brain
- Kidneys
- Liver (correct)
- Blood
Where are enzymes found that destroy some drugs?
Where are enzymes found that destroy some drugs?
- Liver
- Kidneys
- Blood
- Brain (correct)
What happens when enzymes transform molecules of a drug into other forms?
What happens when enzymes transform molecules of a drug into other forms?
- The drug becomes less active
- The drug becomes more active (correct)
- The drug becomes inactive
- The drug remains unchanged
Which factor determines the rate at which a drug in the bloodstream reaches sites of action within the brain?
Which factor determines the rate at which a drug in the bloodstream reaches sites of action within the brain?
Which type of molecules can pass through the cells that line the capillaries in the central nervous system?
Which type of molecules can pass through the cells that line the capillaries in the central nervous system?
Which drug produces a more intense 'rush' due to its faster distribution to the brain?
Which drug produces a more intense 'rush' due to its faster distribution to the brain?
What is the best way to measure the effectiveness of a drug?
What is the best way to measure the effectiveness of a drug?
Which route of drug administration allows for the fastest entry into the bloodstream?
Which route of drug administration allows for the fastest entry into the bloodstream?
Where are most of the sites of action for drugs that affect behavior located?
Where are most of the sites of action for drugs that affect behavior located?
Which type of drug administration allows for the slowest rate of drug absorption into the bloodstream?
Which type of drug administration allows for the slowest rate of drug absorption into the bloodstream?
Which drug is more lipid soluble, heroin or morphine?
Which drug is more lipid soluble, heroin or morphine?
What is the main reason why drug addicts prefer heroin to morphine?
What is the main reason why drug addicts prefer heroin to morphine?
What is the primary role of the blood-brain barrier?
What is the primary role of the blood-brain barrier?
What happens when the maximum effect of a drug is reached?
What happens when the maximum effect of a drug is reached?
Study Notes
Drug Metabolism
- The liver primarily plays an active role in enzymatic deactivation of drugs.
- Enzymes that destroy some drugs are found in the liver.
Drug Transformation
- When enzymes transform molecules of a drug into other forms, it leads to deactivation or activation of the drug.
Drug Distribution
- The rate at which a drug in the bloodstream reaches sites of action within the brain is determined by the blood-brain barrier.
- Lipid-soluble molecules can pass through the cells that line the capillaries in the central nervous system.
Drug Delivery
- Heroin produces a more intense 'rush' due to its faster distribution to the brain compared to morphine.
- The best way to measure the effectiveness of a drug is by observing its effects on the body.
Routes of Administration
- The intravenous route of drug administration allows for the fastest entry into the bloodstream.
- Subcutaneous or transdermal routes of drug administration allow for the slowest rate of drug absorption into the bloodstream.
Sites of Action
- Most sites of action for drugs that affect behavior are located in the brain.
Drug Properties
- Heroin is more lipid-soluble than morphine, which is why drug addicts prefer heroin to morphine.
Blood-Brain Barrier
- The primary role of the blood-brain barrier is to protect the central nervous system from foreign substances.
Drug Effects
- When the maximum effect of a drug is reached, it indicates that the drug has reached the highest concentration in the body.
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Description
Quiz: Test Your Knowledge on Drug Metabolism and Enzymatic Deactivation Discover how well you understand the role of enzymes in drug metabolism and deactivation with this informative quiz. From the liver to the kidneys, explore the key organs involved in drug breakdown and learn about the various ways enzymes can transform drugs into biologically active forms. Challenge your knowledge and enhance your understanding of this vital process in pharmacology.
