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Questions and Answers
Which adverse effect is most associated with the use of COX-2 inhibitors?
Which adverse effect is most associated with the use of COX-2 inhibitors?
- Cardiovascular events (correct)
- Nephrotoxic effects
- Gastrointestinal bleeding
- Bronchospasm
Which drug interaction can exacerbate the nephrotoxic effects of cyclosporine and tacrolimus?
Which drug interaction can exacerbate the nephrotoxic effects of cyclosporine and tacrolimus?
- Antiplatelet agents
- Anticoagulants
- NSAIDs (correct)
- Cytotoxics
Among the listed NSAIDs, which one has the lowest rate of ulceration?
Among the listed NSAIDs, which one has the lowest rate of ulceration?
- Celecoxib (correct)
- Valdecoxib
- Rofecoxib
- Etoricoxib
What is the main concern that led to the restriction or withdrawal of most coxibs from the market?
What is the main concern that led to the restriction or withdrawal of most coxibs from the market?
Which COX-2 inhibitor has the highest degree of selectivity for COX-2 inhibition among those listed?
Which COX-2 inhibitor has the highest degree of selectivity for COX-2 inhibition among those listed?
What is the advantage of treating subjects with 7.5 mg/day of meloxicam compared to piroxicam (20 mg/day)?
What is the advantage of treating subjects with 7.5 mg/day of meloxicam compared to piroxicam (20 mg/day)?
Which NSAID is associated with fewer clinical gastrointestinal symptoms and complications than piroxicam, diclofenac, and naproxen?
Which NSAID is associated with fewer clinical gastrointestinal symptoms and complications than piroxicam, diclofenac, and naproxen?
How does meloxicam interact with antihypertensive and diuretic agents?
How does meloxicam interact with antihypertensive and diuretic agents?
Which drug class may have its antihypertensive effect blunted by meloxicam?
Which drug class may have its antihypertensive effect blunted by meloxicam?
What adverse event may occur if NSAIDs like meloxicam are co-administered with quinolone antimicrobials?
What adverse event may occur if NSAIDs like meloxicam are co-administered with quinolone antimicrobials?
Which potential side effects should be monitored in elderly patients or those with underlying psychiatric disorders when administering indomethacin?
Which potential side effects should be monitored in elderly patients or those with underlying psychiatric disorders when administering indomethacin?
Which NSAID is well-tolerated in patients with familial intestinal polyposis due to sparing renal prostaglandin production?
Which NSAID is well-tolerated in patients with familial intestinal polyposis due to sparing renal prostaglandin production?
What type of adverse effect is common with most traditional NSAIDs during the dosing interval?
What type of adverse effect is common with most traditional NSAIDs during the dosing interval?
Which NSAID has the most COX-2 selective action among traditional NSAIDs?
Which NSAID has the most COX-2 selective action among traditional NSAIDs?
Which NSAID has a longer half-life due to its ability to accumulate in synovial fluid?
Which NSAID has a longer half-life due to its ability to accumulate in synovial fluid?
Which of the following is NOT a class of NSAIDs?
Which of the following is NOT a class of NSAIDs?
Which of the following is an example of a COX-2 inhibitor NSAID?
Which of the following is an example of a COX-2 inhibitor NSAID?
What percentage of people over 65 use NSAIDs with or without a prescription?
What percentage of people over 65 use NSAIDs with or without a prescription?
Which of the following effects is NOT associated with NSAIDs?
Which of the following effects is NOT associated with NSAIDs?
Approximately how many individuals consume NSAIDs every day worldwide?
Approximately how many individuals consume NSAIDs every day worldwide?
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