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Questions and Answers
Which of the following is the functional unit of the kidney responsible for drug excretion?
Which of the following is the functional unit of the kidney responsible for drug excretion?
In which part of the nephron does active secretion of weak electrolyte drugs occur?
In which part of the nephron does active secretion of weak electrolyte drugs occur?
Which process involves re-absorption of water and active secretion of weak acids in the kidney?
Which process involves re-absorption of water and active secretion of weak acids in the kidney?
What is the primary process by which low molecular weight molecules are filtered out of the blood in the kidney?
What is the primary process by which low molecular weight molecules are filtered out of the blood in the kidney?
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In the process of drug excretion, which part of the nephron is responsible for the additional reabsorption of water?
In the process of drug excretion, which part of the nephron is responsible for the additional reabsorption of water?
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What is the primary process by which low molecular weight molecules are filtered out of the blood in the kidney during drug excretion?
What is the primary process by which low molecular weight molecules are filtered out of the blood in the kidney during drug excretion?
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Which renal excretion process involves the active secretion of weak electrolyte drugs, especially weak acids, in the kidney?
Which renal excretion process involves the active secretion of weak electrolyte drugs, especially weak acids, in the kidney?
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What is the normal range of glomerular filtration rate in healthy individuals during drug excretion?
What is the normal range of glomerular filtration rate in healthy individuals during drug excretion?
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In drug excretion, where does the passive reabsorption of water and lipid-soluble drugs occur in the nephron?
In drug excretion, where does the passive reabsorption of water and lipid-soluble drugs occur in the nephron?
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Study Notes
Kidney Function and Drug Excretion
- The functional unit of the kidney responsible for drug excretion is the nephron.
- Active secretion of weak electrolyte drugs occurs primarily in the proximal convoluted tubule of the nephron.
- The nephron is responsible for re-absorption of water and active secretion of weak acids through its tubular segments, particularly the proximal tubule.
- Low molecular weight molecules are primarily filtered out of the blood in the kidney via the glomerulus through the process of filtration.
- The distal convoluted tubule and collecting duct are involved in additional reabsorption of water during drug excretion.
- Filtration of low molecular weight molecules in the kidney occurs during drug excretion at the glomerulus.
- The renal excretion process involves active secretion of weak electrolyte drugs, especially weak acids, mainly in the proximal convoluted tubule.
- The normal range of glomerular filtration rate (GFR) in healthy individuals is approximately 90 to 120 mL/min during drug excretion.
- Passive reabsorption of water and lipid-soluble drugs takes place primarily in the proximal convoluted tubule and collecting duct of the nephron.
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Description
Test your knowledge on drug excretion and the major renal excretion processes. Understand the role of the kidney and its components in excreting drugs and the processes of glomerular filtration, tubular secretion, and tubular re-absorption.
