Drug Classifications - Sedative Hypnotics

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Questions and Answers

What is Temazepam commonly known as?

  • Restoril (correct)
  • Valium
  • Haldol
  • Ambien

What type of drug is Phenobarbital?

Anticonvulsant Barbiturate

Chlorpromazine is classified as what type of tranquilizer?

Major tranquilizer

What is the primary use for Cyclobenzaprine?

<p>Muscle relaxant</p> Signup and view all the answers

What class of medication is Amitriptyline?

<p>Tricyclic antidepressant</p> Signup and view all the answers

What is Haloperidol used for?

<p>Major tranquilizer</p> Signup and view all the answers

What is Midazolam used for?

<p>SA sedative</p> Signup and view all the answers

What type of drug is Sertraline?

<p>Antidepressant</p> Signup and view all the answers

What is Olanzapine primarily used for?

<p>Major tranquilizer</p> Signup and view all the answers

Diseazepam is long-acting and can be used for status epilepticus. What is its brand name?

<p>Valium</p> Signup and view all the answers

What does flurazepam do?

<p>Approved as hypnotic</p> Signup and view all the answers

What is the primary use of Zolpidem?

<p>Hypnotic</p> Signup and view all the answers

What type of drug is buspirone?

<p>Miscellaneous anti-anxiety</p> Signup and view all the answers

Flumazenil is known as the _____ of benzodiazepine sedation.

<p>reversal/antidote</p> Signup and view all the answers

Chlordiazepoxide is a short-acting benzodiazepine.

<p>False (B)</p> Signup and view all the answers

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Study Notes

Sedative - Hypnotics Overview

  • Sedative-hypnotics are classified mainly into benzodiazepines, barbiturates, and miscellaneous hypnotics.
  • Benzodiazepines are often used for anxiety, sleep issues, and seizure management due to their calming effects.

Key Benzodiazepines

  • Temazepam (Restoril): Short-acting hypnotic for sleep.
  • Lorazepam (Ativan): Short-acting, used in status epilepticus; requires refrigeration.
  • Oxazepam (Serax): Short-acting sedative, utilized for anxiety and sleep.
  • Diazepam (Valium): Long-acting, indicated for status epilepticus and pre-procedure sedation.
  • Clorazepate (Tranxene): Long-acting, often used in alcohol withdrawal treatment.
  • Midazolam (Versed): Short-acting, administered before procedures.

Key Barbiturates

  • Phenobarbital: Anticonvulsant barbiturate; can be used as a sedative.
  • Thiopental (Pentothal): Anesthetic used in surgeries and the death penalty; also causes hyperalgesia.
  • Pentobarbital (Nembutal): Hypnotic barbiturate for severe insomnia.

Major Tranquilizers

  • Chlorpromazine (Thorazine): Phenothiazine major tranquilizer for severe mental illnesses.
  • Haloperidol (Haldol): Butyrophenone tranquilizer with low anticholinergic activity.
  • Olanzapine (Zyprexa): Atypical antipsychotic used for long-term management of disorders.

Miscellaneous Hypnotics

  • Zolpidem (Ambien): Most prescribed hypnotic; increases total sleep time.
  • Eszopiclone (Lunesta): Known for causing a bitter taste; effective as a sleep aid.
  • Zaleplon (Sonata): Short-acting hypnotic for insomnia; effective for difficulty falling asleep.
  • Buspirone (Buspar): Non-controlled antianxiety medication, takes about 7 days to be effective.

Important Considerations

  • Flumazenil: Antidote for benzodiazepine overdose or sedation.
  • Chloral Hydrate (Noctec): Miscellaneous hypnotic that can be lethal if combined with alcohol.
  • Tricyclic Antidepressants: Amintriptyline (Elavil) is a common example but primarily used for depression.

Safety Notes

  • Benzodiazepines can lead to dependency; careful management is required, especially in patients with addiction history.
  • Barbiturates have a higher risk of overdose compared to benzodiazepines due to their narrow therapeutic window.

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