Drug Classification Quiz: Antihistamines and their Effects
18 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the mechanism of action of histamine on H1 receptors?

  • Bronchodilatation (correct)
  • Vasodilation
  • Vasoconstriction
  • Increased cardiac contractility

Which receptor subtype does epinephrine act on to induce vasoconstriction in anaphylaxis?

  • Beta2-adrenoceptors
  • Histamine receptors
  • Alpha-adrenoceptors (correct)
  • Beta1-adrenoceptors

Why is epinephrine considered life-saving in the treatment of anaphylaxis?

  • It stimulates vasoconstriction (correct)
  • It induces bronchospasm
  • It inhibits histamine release
  • It increases vascular leakage

How are allergic diseases diagnosed according to the text?

<p>Skin prick testing (B)</p> Signup and view all the answers

Which drug is administered to inhibit vasodilation, vascular leakage, and bronchospasm during anaphylaxis?

<p>Diphenhydramine (C)</p> Signup and view all the answers

What is the primary function of beta2 adrenoceptor agonists during anaphylaxis?

<p>Bronchodilation (B)</p> Signup and view all the answers

Which receptor type is responsible for causing bronchoconstriction in hypersensitivity type I reactions?

<p>H1 receptors (D)</p> Signup and view all the answers

In allergic reactions, which molecule stored in mast cell granules acts on specific histamine receptors?

<p>Histamine (B)</p> Signup and view all the answers

Anaphylactic reactions are mediated by which type of antibodies?

<p>IgE antibodies (B)</p> Signup and view all the answers

What is the central role of histamine in mild allergic reactions?

<p>Increasing capillary permeability and vasodilatation (D)</p> Signup and view all the answers

Which symptom is NOT commonly associated with anaphylaxis?

<p>Myocardial infarction (B)</p> Signup and view all the answers

What happens when allergen cross-links IgE on mast cells during hypersensitivity type I reactions?

<p>Mediator release from mast cells is triggered (D)</p> Signup and view all the answers

Which of the following is a characteristic of 'inverse agonists'?

<p>They induce a pharmacological response opposite to that of the agonist. (B)</p> Signup and view all the answers

Which type of anti-histamines are known for exhibiting additional anti-inflammatory effects?

<p>Second generation anti-histamines (B)</p> Signup and view all the answers

What is a common adverse effect associated with topical calcineurin inhibitors like Tacrolimus?

<p>Burning sensation in the skin (B)</p> Signup and view all the answers

Which of the following statements about Terfenadine is true?

<p>It can be subject to a clinically significant drug-drug interaction. (A)</p> Signup and view all the answers

Which of the following anti-histamines is NOT a second-generation type?

<p>Diphenhydramine (C)</p> Signup and view all the answers

What makes Loratadine distinct from other anti-histamines in terms of crossing the blood-brain barrier?

<p>It is lipophobic and hence does not cross the blood-brain barrier. (C)</p> Signup and view all the answers

More Like This

Antihistamines Flashcards
9 questions

Antihistamines Flashcards

LavishDiopside625 avatar
LavishDiopside625
Allegra Drug Card Flashcards
10 questions
Use Quizgecko on...
Browser
Browser