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Drug Classification in Schedules 1, 2, and 3

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What is the main characteristic of Schedule 3 drugs?

They can be verbally ordered and refilled up to five times within 6 months

Which category for pregnancy indicates that controlled studies fail to demonstrate a risk to the fetus in the first trimester?

Category A

What is a defining attribute of Schedule 1 drugs?

Not available for regular use except for investigational purposes

Which drugs have a low potential for abuse and limited physical dependence?

Lorazepam (Ativan)

What differentiates Schedule 2 drugs from Schedule 3 drugs?

They require a written prescription within 72 hours

What is the primary feature of Schedule 5 drugs?

Antitussives and antidiarrheals

Under which category for pregnancy does the possibility of fetal harm appear remote?

Category B

What is a distinguishing characteristic of Schedule 2 drugs?

Valid medical use but high potential for abuse

Which drugs are included in Schedule 4?

Lorazepam (Ativan)

What sets Schedule 3 drugs apart from Schedule 4 drugs?

Low potential for abuse and limited physical dependence

Which group of individuals is mentioned to have a decreased risk of suicide when taking SSRIs?

Adults aged 25-64

What somatic symptom is most commonly seen in children and teenagers with no identifiable physical cause?

Abdominal pain

What is the boxed warning associated with the use of antidepressants in children, adolescents, and young adults?

Increased risk of suicidal thinking and behavior

Which type of medication can cause QT interval prolongation and neuroleptic malignant syndrome?

Antipsychotics

What is the first-line therapy recommended by the APA for Obsessive-Compulsive Disorder (OCD)?

Fluoxetine

Which age group is mentioned to have an increased risk of suicidal ideation with the use of antidepressants?

Teenagers aged 19-25

Which medication is considered 1st line for treating elderly depression?

Citalopram

What is the main adverse event associated with Benzodiazepines (BZDs)?

Ataxia

Apart from abdominal pain, what is another common somatic symptom seen in children and teenagers with no physiological cause?

Headaches

Which medication can be an option for individuals with a history of substance abuse when treating anxiety?

Buspirone

What is the primary consideration when prescribing drugs in pregnancy?

Minimizing the risk of fetal harm

What is the primary purpose of Phase III Clinical Trials?

To compare the new drug with existing treatments in a large-scale trial

What is the primary contributor to morbidity and mortality in elderly individuals?

Polypharmacy

What is the primary cause of preventable medication problems in elderly individuals?

All of the above

What is the primary source of polypharmacy in elderly individuals?

All of the above

What is the primary consequence of polypharmacy in elderly individuals?

Increased risk of hospital admissions

What is the primary role of Phase IV Clinical Trials?

To monitor the long-term safety and efficacy of the drug

What is the primary consideration when evaluating the safety of a drug during pregnancy?

The drug's potential risk to the fetus

What is the primary purpose of Preclinical Trials?

To evaluate the efficacy and toxic effects of the drug in animals

What is the primary concern with NSAIDs in elderly individuals?

Gastrointestinal complications

Which type of antidepressant is known to be metabolized by the liver and requires titration before discontinuation?

SNRIs

Which class of antidepressants is associated with adverse effects such as nausea, insomnia, and decreased libido, especially in serotonin storm and bipolar patients?

SNRIs

Which antidepressant class is known to increase the relative concentrations of both serotonin and norepinephrine, with a varying degree of serotonergic or noradrenergic activity depending on the dose?

SNRIs

Which class of antidepressants is considered 3rd line and is primarily used as potent inhibitors of norepinephrine reuptake with fewer effects on serotonin?

TCAs

Which antidepressant category is known for causing cholinergic side effects and being useful for pain control?

TCAs

Which type of antidepressants is similar to TCAs in its effects but causes sedation, increased appetite, and reduced insomnia?

α2-Noradrenergic antagonists/mixed serotonin blockers

Which antidepressant acts as a weak serotonin receptor antagonist and is highly sedating at therapeutic doses, commonly used to treat insomnia?

Serotonin 2A antagonists

Which antidepressant class leads to decreased degradation of norepinephrine, serotonin, and dopamine in the synaptic cleft, but is associated with severe hypertensive crisis?

MAOIs

Which class of antidepressants is known for being broad-spectrum but requires the strict avoidance of tyramine-containing foods due to the risk of hypertensive crisis?

MAOIs

Which antidepressant category is highly sedating at therapeutic doses and often used to treat insomnia?

Serotonin 2A antagonists

Which medication can be considered first-line for preventively treating migraines?

Metoprolol

What is a common adverse reaction to triptans indicated in the text?

Chest pain

If a patient experiences heartburn as a side effect, which medication could they potentially be using?

Propranolol

What symptom should raise concern about a possible severe headache based on the text?

Stiff neck

Which class of medications is recommended as a second-line abortive treatment for migraines in the text?

Ubrogepant

What adverse reaction might justify the avoidance of triptans in a patient with coronary artery disease?

Increased blood pressure

Which medication is a drug of choice in status migrainosus and for triptan resistance or failure?

Dihydroergotamine

If a patient reports weakness and numbness, which red flag headache symptom should be considered based on the text?

Headache associated with neurological symptoms

Which non-pharmacological intervention is recommended as a first-line preventive treatment in the text?

CBT

If a patient experiences insomnia following medication use, which drug may be the culprit according to the text?

Venlafaxine

What is the primary reason for closely monitoring serum lithium levels?

To prevent lithium toxicity

What is the recommended range for serum lithium concentrations in most patients for a therapeutic response?

0.8-1.2 mEq/L

What condition contraindicates the use of lithium?

Renal disease

Which age group needs dose adjustments when prescribing lithium?

Pediatric and older adult patients

In the treatment of acute severe mania, lithium is typically administered in combination with which type of drug?

Antipsychotics

What is a significant interaction to be mindful of when prescribing lithium?

Interactions with calcium channel blockers

What is a common side effect of lithium therapy related to its serum levels?

Lithium toxicity

Why is it essential to adjust doses of drugs interacting with lithium?

To prevent drug interactions

For which purpose is lithium primarily used in treating bipolar disorder?

Managing manic episodes

In which patients might a therapeutic response be observed at lower serum lithium levels like 0.6 mEq/L?

Elderly individuals

Learn about the classification of drugs in Schedules 1, 2, and 3 based on their potential for abuse and medical use. Understand the restrictions and regulations surrounding the prescription and use of drugs in each schedule.

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