60 Questions
What is the main characteristic of Schedule 3 drugs?
They can be verbally ordered and refilled up to five times within 6 months
Which category for pregnancy indicates that controlled studies fail to demonstrate a risk to the fetus in the first trimester?
Category A
What is a defining attribute of Schedule 1 drugs?
Not available for regular use except for investigational purposes
Which drugs have a low potential for abuse and limited physical dependence?
Lorazepam (Ativan)
What differentiates Schedule 2 drugs from Schedule 3 drugs?
They require a written prescription within 72 hours
What is the primary feature of Schedule 5 drugs?
Antitussives and antidiarrheals
Under which category for pregnancy does the possibility of fetal harm appear remote?
Category B
What is a distinguishing characteristic of Schedule 2 drugs?
Valid medical use but high potential for abuse
Which drugs are included in Schedule 4?
Lorazepam (Ativan)
What sets Schedule 3 drugs apart from Schedule 4 drugs?
Low potential for abuse and limited physical dependence
Which group of individuals is mentioned to have a decreased risk of suicide when taking SSRIs?
Adults aged 25-64
What somatic symptom is most commonly seen in children and teenagers with no identifiable physical cause?
Abdominal pain
What is the boxed warning associated with the use of antidepressants in children, adolescents, and young adults?
Increased risk of suicidal thinking and behavior
Which type of medication can cause QT interval prolongation and neuroleptic malignant syndrome?
Antipsychotics
What is the first-line therapy recommended by the APA for Obsessive-Compulsive Disorder (OCD)?
Fluoxetine
Which age group is mentioned to have an increased risk of suicidal ideation with the use of antidepressants?
Teenagers aged 19-25
Which medication is considered 1st line for treating elderly depression?
Citalopram
What is the main adverse event associated with Benzodiazepines (BZDs)?
Ataxia
Apart from abdominal pain, what is another common somatic symptom seen in children and teenagers with no physiological cause?
Headaches
Which medication can be an option for individuals with a history of substance abuse when treating anxiety?
Buspirone
What is the primary consideration when prescribing drugs in pregnancy?
Minimizing the risk of fetal harm
What is the primary purpose of Phase III Clinical Trials?
To compare the new drug with existing treatments in a large-scale trial
What is the primary contributor to morbidity and mortality in elderly individuals?
Polypharmacy
What is the primary cause of preventable medication problems in elderly individuals?
All of the above
What is the primary source of polypharmacy in elderly individuals?
All of the above
What is the primary consequence of polypharmacy in elderly individuals?
Increased risk of hospital admissions
What is the primary role of Phase IV Clinical Trials?
To monitor the long-term safety and efficacy of the drug
What is the primary consideration when evaluating the safety of a drug during pregnancy?
The drug's potential risk to the fetus
What is the primary purpose of Preclinical Trials?
To evaluate the efficacy and toxic effects of the drug in animals
What is the primary concern with NSAIDs in elderly individuals?
Gastrointestinal complications
Which type of antidepressant is known to be metabolized by the liver and requires titration before discontinuation?
SNRIs
Which class of antidepressants is associated with adverse effects such as nausea, insomnia, and decreased libido, especially in serotonin storm and bipolar patients?
SNRIs
Which antidepressant class is known to increase the relative concentrations of both serotonin and norepinephrine, with a varying degree of serotonergic or noradrenergic activity depending on the dose?
SNRIs
Which class of antidepressants is considered 3rd line and is primarily used as potent inhibitors of norepinephrine reuptake with fewer effects on serotonin?
TCAs
Which antidepressant category is known for causing cholinergic side effects and being useful for pain control?
TCAs
Which type of antidepressants is similar to TCAs in its effects but causes sedation, increased appetite, and reduced insomnia?
α2-Noradrenergic antagonists/mixed serotonin blockers
Which antidepressant acts as a weak serotonin receptor antagonist and is highly sedating at therapeutic doses, commonly used to treat insomnia?
Serotonin 2A antagonists
Which antidepressant class leads to decreased degradation of norepinephrine, serotonin, and dopamine in the synaptic cleft, but is associated with severe hypertensive crisis?
MAOIs
Which class of antidepressants is known for being broad-spectrum but requires the strict avoidance of tyramine-containing foods due to the risk of hypertensive crisis?
MAOIs
Which antidepressant category is highly sedating at therapeutic doses and often used to treat insomnia?
Serotonin 2A antagonists
Which medication can be considered first-line for preventively treating migraines?
Metoprolol
What is a common adverse reaction to triptans indicated in the text?
Chest pain
If a patient experiences heartburn as a side effect, which medication could they potentially be using?
Propranolol
What symptom should raise concern about a possible severe headache based on the text?
Stiff neck
Which class of medications is recommended as a second-line abortive treatment for migraines in the text?
Ubrogepant
What adverse reaction might justify the avoidance of triptans in a patient with coronary artery disease?
Increased blood pressure
Which medication is a drug of choice in status migrainosus and for triptan resistance or failure?
Dihydroergotamine
If a patient reports weakness and numbness, which red flag headache symptom should be considered based on the text?
Headache associated with neurological symptoms
Which non-pharmacological intervention is recommended as a first-line preventive treatment in the text?
CBT
If a patient experiences insomnia following medication use, which drug may be the culprit according to the text?
Venlafaxine
What is the primary reason for closely monitoring serum lithium levels?
To prevent lithium toxicity
What is the recommended range for serum lithium concentrations in most patients for a therapeutic response?
0.8-1.2 mEq/L
What condition contraindicates the use of lithium?
Renal disease
Which age group needs dose adjustments when prescribing lithium?
Pediatric and older adult patients
In the treatment of acute severe mania, lithium is typically administered in combination with which type of drug?
Antipsychotics
What is a significant interaction to be mindful of when prescribing lithium?
Interactions with calcium channel blockers
What is a common side effect of lithium therapy related to its serum levels?
Lithium toxicity
Why is it essential to adjust doses of drugs interacting with lithium?
To prevent drug interactions
For which purpose is lithium primarily used in treating bipolar disorder?
Managing manic episodes
In which patients might a therapeutic response be observed at lower serum lithium levels like 0.6 mEq/L?
Elderly individuals
Learn about the classification of drugs in Schedules 1, 2, and 3 based on their potential for abuse and medical use. Understand the restrictions and regulations surrounding the prescription and use of drugs in each schedule.
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