7 Medicines and Pharmacology

Which medication is known for its selective inhibition of cyclooxygenase 2 and is associated with fewer gastrointestinal side effects compared to nonselective agents?

What is the most significant adverse effect associated with the use of infliximab in patients with inflammatory bowel disease?

Which medication can cause extrapyramidal manifestations such as tardive dyskinesia and should be managed with Benadryl?

Which medication is a derivative of prostaglandin E1 and is used to prevent peptic ulcer disease in patients on chronic NSAIDs?

What is the most common side effect associated with gadolinium contrast?

Which medication is known to cause metabolic alkalosis, hypokalemia, and ototoxicity as side effects due to over-diuresis?

Which medication is an antibody to TNF-alpha given intravenously and is used in the treatment of inflammatory bowel disease?

What is the most common side effect associated with iodine contrast?

Which medication inhibits aldosterone and can cause metabolic acidosis and hyperkalemia as side effects due to over-diuresis?

What is the first acid-base disorder that occurs in a patient with ASA poisoning?

Which route of drug administration bypasses the liver and has higher bioavailability compared to oral drugs?

What is largely responsible for binding drugs such as penicillins and warfarin?

Which drug can displace unconjugated bilirubin from albumin in newborns and should be avoided in this population?

Which type of drug kinetics involves a constant amount of drug being eliminated regardless of the dose?

How many half-lives does it take for a drug to reach steady state?

What does the volume of distribution of a drug represent?

Which route of administration involves drug absorption based on lipid solubility through the epidermis?

Which type of drug is restricted to nonionized, lipid-soluble drugs for absorption into the cerebrospinal fluid (CSF)?

Which drug is stored in bone and follows zero-order kinetics for elimination?

Which drug has the potential to cause kernicterus in newborns due to displacement of unconjugated bilirubin from albumin?

What is the fraction of unchanged drug reaching the systemic circulation known as?

Which drug level is defined as the level at which death occurs in 50% of patients?

What effect is seen at an unusually low dose of a drug?

Which phase of drug metabolism involves demethylation, oxidation, reduction, and hydrolysis reactions?

Which of the following is an inhibitor of P-450 system?

What is the most important organ for eliminating most drugs?

What is the end product of purine metabolism that causes gout?

What medication binds tubulin and inhibits migration of white blood cells?

Which lipid-lowering agent binds bile acids in the gut, forcing the body to resynthesize bile acids from cholesterol?

Which drug is used to treat torsades de pointes (ventricular tachycardia)?