Podcast
Questions and Answers
What is the repetitive nucleotide sequence found in human telomeres?
What is the repetitive nucleotide sequence found in human telomeres?
- GGTTAC
- AATTCG
- CTAAGG
- TTAGGG (correct)
Which Nobel laureates were awarded for the discovery of the telomerase enzyme?
Which Nobel laureates were awarded for the discovery of the telomerase enzyme?
- Blackburn, Carol Greider, and Watson
- Blackburn, Greider, and Szostak (correct)
- Watson, Szostak, and Greider
- Szostak, Blackburn, and Watson
Which protein complex is responsible for maintaining the G-quadruplex structure of telomeres?
Which protein complex is responsible for maintaining the G-quadruplex structure of telomeres?
- Shelterin (telosome) (correct)
- TRF1 and TRF2
- RAP-1 and POT1
- TIN2 and TPP1
What is the function of RAP-1 within the Shelterin complex?
What is the function of RAP-1 within the Shelterin complex?
Which structure is thought to be adopted by telomere DNA?
Which structure is thought to be adopted by telomere DNA?
What is a major cause of cellular aging associated with telomeres?
What is a major cause of cellular aging associated with telomeres?
What process is triggered when the telomere becomes too short?
What process is triggered when the telomere becomes too short?
Why are the ends of linear chromosomes an issue during DNA replication?
Why are the ends of linear chromosomes an issue during DNA replication?
What are the small pieces produced on the lagging strand during DNA replication called?
What are the small pieces produced on the lagging strand during DNA replication called?
What is the name of the strand that is made continuously during DNA replication?
What is the name of the strand that is made continuously during DNA replication?
How many times can cells normally divide before telomeres become too short, leading to cell senescence and death?
How many times can cells normally divide before telomeres become too short, leading to cell senescence and death?
According to the conclusion, how has telomere shortening been proposed to function?
According to the conclusion, how has telomere shortening been proposed to function?
What is the function of telomerase in cells?
What is the function of telomerase in cells?
Which cell types typically exhibit high telomerase activity?
Which cell types typically exhibit high telomerase activity?
What does TERC do in the telomerase structure?
What does TERC do in the telomerase structure?
What happens to telomeres as we age?
What happens to telomeres as we age?
What contributes to telomere shortening according to the text?
What contributes to telomere shortening according to the text?
Why is telomerase referred to as a 'cellular immortalizing enzyme'?
Why is telomerase referred to as a 'cellular immortalizing enzyme'?
