Questions and Answers
What is the drug class of Doxazosin?
What is the mechanism of action of Doxazosin?
Decreased peripheral vascular resistance (PVR) and vasodilation
What are some indications for Doxazosin?
Which of the following are side effects of Doxazosin?
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What are the contraindications for using Doxazosin?
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What is the recommended dose for benign prostatic hyperplasia?
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What precautions should be taken when using Doxazosin?
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Study Notes
Drug Class
- Doxazosin belongs to the "zosin" class of medications, which are alpha blockers.
- Acts as an adrenergic antagonist specifically targeting alpha-1 receptors.
Mechanism of Action
- Decreases peripheral vascular resistance (PVR) without a significant reflex increase in cardiac output due to sparing alpha-2 receptors.
- Vasodilation occurs as it relaxes blood vessels, facilitating easier blood flow.
- This mechanism contributes to lower blood pressure levels.
Indications
- Prescribed for managing hypertension.
- Effective in treating benign prostatic hyperplasia (BPH).
- Can be used for Raynaud's disease, a condition affecting blood flow.
Side Effects
- Common side effects include orthostatic hypotension, leading to potential dizziness or vertigo.
- Patients may experience tachycardia and hypotension as well.
Contraindications
- Avoid use in individuals allergic to doxazosin or other alpha blockers such as prazosin or terazosin.
Dose/Route
- For benign prostatic hyperplasia, the recommended dose ranges from 1-8 mg once daily.
- For hypertension, doses can range from 1-16 mg once daily.
Precautions
- Elderly patients with high blood pressure are particularly susceptible to dizziness, lightheadedness, or fainting due to increased sensitivity to doxazosin.
- Caution is advised when using alcohol or tobacco, as they may lead to drug interactions.
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Description
Test your knowledge on Doxazosin, an alpha blocker, with these flashcards. Explore its drug class, mechanism of action, and clinical indications for use. Perfect for students or healthcare professionals looking to reinforce their understanding of this medication.
