Dose-Response Relationships in Drug Distribution Quiz

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Which of the following best describes the initial symptoms experienced by Mr. F. after consuming the asparagus?

Dizziness and headache

Blurred vision and double vision (correct)

Difficulty breathing and chest pain

Nausea and vomiting

What did Mr. F. do after realizing that the asparagus smelled funny?

He tasted it and swallowed it

He ignored it and finished his dinner

He rinsed it under water and disposed of it (correct)

He threw it away immediately

What is the main focus of psychopharmacology?

The effects of drugs on the nervous system and behavior (correct)

The effects of drugs on the cardiovascular system

The study of neurological diseases

The study of asparagus and its effects on health

Which of the following is the definition of a drug according to pharmacologists?

An exogenous chemical not necessary for normal cellular functioning that significantly alters the functions of certain cells of the body when taken in relatively low doses (C) Signup and view all the answers

What is the study of the effects of drugs on the nervous system and behavior called?

Psychopharmacology (C) Signup and view all the answers

Which of the following is NOT considered a drug according to the definition provided?

Neurotransmitters (A) Signup and view all the answers

What are the sites of action of drugs?

The points at which molecules of drugs interact with molecules located on or in cells of the body (D) Signup and view all the answers

Which route of drug administration is commonly used to treat lung disorders?

Inhalation (B) Signup and view all the answers

Which route of drug administration involves placing drugs beneath the tongue?

Sublingual administration (A) Signup and view all the answers

Which route of drug administration involves injecting drugs directly into the brain?

Intracerebral administration (D) Signup and view all the answers

Which route of drug administration involves absorbing drugs through the skin?

Topical administration (D) Signup and view all the answers

Which route of drug administration allows for the most rapid entry of drugs into the brain?

Intravenous injection (C) Signup and view all the answers

What is the most important factor that determines the rate at which a drug reaches sites of action within the brain?

Lipid solubility (A) Signup and view all the answers

Which drug is more lipid soluble, heroin or morphine?

Heroin (B) Signup and view all the answers

How are drugs eventually eliminated from the body?

They are deactivated by enzymes (C) Signup and view all the answers

Which route of administration is the fastest and allows the drug to reach the brain within a few seconds?

Intravenous (IV) injection (B) Signup and view all the answers

What is the process by which drugs are absorbed, distributed within the body, metabolized, and excreted called?

Pharmacokinetics (A) Signup and view all the answers

Which section of the chapter discusses the basic principles of psychopharmacology, including the routes of administration and the fate of drugs in the body?

The first section (A) Signup and view all the answers

Which of the following is NOT a topic discussed in Chapters 16 and 17?

Drug abuse (C) Signup and view all the answers

Which of the following is NOT a way in which drugs exert their effects in the central nervous system?

Binding with enzymes involved in the production of neurotransmitters (C) Signup and view all the answers

What is the relationship between a drug's affinity and its effectiveness?

A drug with high affinity is more effective than a drug with low affinity (D) Signup and view all the answers

What is one of the goals of research by drug companies?

To find drugs with high affinities for sites of action that produce therapeutic effects (D) Signup and view all the answers

Which of the following statements about drugs and their distribution throughout the body is true?

Smaller subjects require a larger quantity of a drug to achieve the same concentration as larger subjects. (B) Signup and view all the answers

What happens when the dose of a drug reaches the point of maximum effect?

Increasing the dose of the drug does not produce any more effect. (A) Signup and view all the answers

What is the margin of safety of a drug?

The difference between the dose that produces therapeutic effects and the dose that produces adverse side effects. (D) Signup and view all the answers

What is the therapeutic index of a drug?

The ratio of the dose that produces therapeutic effects to the dose that produces toxic effects. (C) Signup and view all the answers