Dose-Response Curve

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Which of the following statements accurately describes the dose-response curve for the analgesic effect of morphine?

The curve indicates the drug's margin of safety.

What does a drug's margin of safety indicate?

The difference between the therapeutic and adverse effects of the drug.

What is the therapeutic index of a drug?

The ratio of the dose that produces desired effects to the dose that produces toxic effects in 50 percent of the animals.

Which of the following best describes the compensatory mechanisms discussed in the text?

They decrease the effectiveness of drug binding with receptors

What is the difference between tolerance and sensitization?

Tolerance occurs when larger doses of a drug are needed to achieve the same effect, while sensitization occurs when smaller doses of a drug are needed to achieve a larger effect

What is the purpose of using placebos in drug research?

To determine if a drug has a specific physiological effect

What is a withdrawal symptom?

The appearance of symptoms opposite to those produced by a drug when it is administered repeatedly

Which of the following best describes the therapeutic index of a drug?

The ratio between the dose that produces the desired effect in 50 percent of the animals and the dose that produces toxic effects in 50 percent of the animals.

Why is an accidental overdose of a barbiturate more likely to have tragic effects than a similar overdose of Valium?

Barbiturates have a lower therapeutic index than Valium.

What are the two reasons that drugs vary in their effectiveness?

Different drugs may have different sites of action and different affinities for their binding sites.

What is the difference between tolerance and sensitization?

Tolerance is a decrease in the effectiveness of a drug that is administered repeatedly, while sensitization is an increase in the effectiveness of a drug that is administered repeatedly.

Quiz: Understanding the Dose-Response Curve for Morphine's Analgesic and Depressive Effects Test your knowledge on the dose-response curve for the analgesic effect of morphine and its impact on respiration. Explore concepts such as drug high, margin of safety, and the relationship between dose and response. Get ready to dive into the fascinating world of psychopharmacology.

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