17 Questions
What is the characteristic of a drug that has a higher efficacy?
Giving a response that cannot be produced by another drug of a lower efficacy
Which of the following best describes the importance of efficacy for a physician and patient?
It is a more important drug characteristic than potency
What is the primary purpose of a dose response curve?
To demonstrate the relationship between the doses of a drug and the responses produced by these doses
What is indicated by a steep slope in the dose-response curve?
A narrow margin of safety
What is the term for the variation in response to a drug among different individuals or in the same individual over time?
Biological variation
What is represented on the x-axis of a dose response curve?
Potency
Which of the following factors contributes to biological variation?
Age of the individual
What is the importance of potency in clinical practice?
It has little clinical significance, but low potency is a disadvantage if the dose is too large
What is the median effective dose (ED50)?
The dose at which 50% of the population or sample manifests a given effect
What is represented by the horizontal bracket in the expression of biological variation?
A certain response that can be achieved by a range of doses
What is efficacy in the context of a dose response curve?
The relative ability of a drug to produce a maximum functional response
What is the characteristic of a highly potent drug?
It produces a maximum functional response at low concentrations
What is the interval of time between doses in the preparation of a dose response curve for Epinephrine?
30 minutes
What is the primary purpose of preparing a dose response curve?
To determine the relationship between the dose of a drug and its response
Which of the following is a characteristic of a dose response curve?
The response increases with an increase in dose
What is the ED50 of a drug?
The dose of the drug that produces 50% of the maximum response
Which of the following is a measure of a drug's efficacy?
The maximum response produced by the drug
Test your understanding of dose response curves, including their definition, types, and characteristics. Learn about the criteria of dose response curves, ED50, and LD50. Evaluate your knowledge of pharmacology and toxicology concepts.
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