Dornase Alfa Overview and Usage
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Questions and Answers

What is the generic name for Dornase?

  • Mucolytic
  • Action
  • Pulmozyme
  • Donase Alfa (correct)
  • What is the trade name for Dornase?

  • Pulmozyme (correct)
  • Mucolytic
  • Donase Alfa
  • Action
  • What classification does Dornase belong to?

    Mucolytic

    What is the action of Dornase?

    <p>Enzyme action which digests DNA in infected sputum.</p> Signup and view all the answers

    What is the dose of Dornase?

    <p>Ampule containing 2.5 mg in 2.5 ml of clear colorless solution.</p> Signup and view all the answers

    The solution of Dornase should be stored at room temperature.

    <p>False</p> Signup and view all the answers

    Dornase should not be mixed with other medications.

    <p>True</p> Signup and view all the answers

    What are the approved nebulizers for Dornase?

    <p>PARI LC (reusable) with PARI PRO NEB compressor.</p> Signup and view all the answers

    Study Notes

    Dornase Alfa Overview

    • Generic Name: Dornase Alfa is the generic name for the medication used in cystic fibrosis treatment.
    • Trade Name: The trade name for Dornase Alfa is Pulmozyme.

    Classification and Action

    • Classification: Dornase Alfa falls under the mucolytic category, which refers to drugs that thin mucus.
    • Mechanism of Action: The enzyme works by digesting DNA in the infected sputum, helping to alleviate respiratory issues associated with cystic fibrosis.

    Dosage and Administration

    • Dose Information: Administered via an ampule containing 2.5 mg in 2.5 ml of a clear, colorless solution (Qd - once daily).

    Storage Requirements

    • Storage Guidelines: The solution must be refrigerated and should be protected from light to maintain efficacy. Any medication left at room temperature or displaying discoloration should be discarded.

    Precautions

    • Medication Mixing: Dornase Alfa should not be mixed with other medications to avoid interactions.

    Equipment

    • Approved Nebulizers: Recommended for use with PARI LC (reusable) nebulizers when paired with the PARI PRO NEB compressor.

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    Description

    This quiz provides an overview of Dornase Alfa, a mucolytic medication used in treating cystic fibrosis. It covers its classification, mechanism of action, dosage, administration guidelines, and storage requirements. Test your knowledge on the specifics of this important therapeutic agent.

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