Dobutamine Flashcards
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Dobutamine Flashcards

Created by
@EnthralledSaxhorn

Questions and Answers

What class of drug is Dobutamine?

  • Antihypertensive
  • Diuretic
  • Anxiolytic
  • Sympathomimetic (correct)
  • What are the trade names for Dobutamine?

    Dobutrex

    What is the mechanism of action (MoA) of Dobutamine?

    Increases cardiac output and decreases pulmonary wedge pressure by acting on myocardial beta and alpha adrenergic receptors.

    What are the primary uses or indications for Dobutamine?

    <p>To increase cardiac output in CHF/cardiogenic shock</p> Signup and view all the answers

    What is the adult dosage for Dobutamine?

    <p>2 - 20 mcg/kg/min, titrated to desired effect</p> Signup and view all the answers

    What is the pediatric dosage for Dobutamine?

    <p>2 - 20 mcg/kg/min, titrated to desired effect</p> Signup and view all the answers

    Which of the following are contraindications for Dobutamine? (Select all that apply)

    <p>Idiopathic hypertrophic subaortic stenosis</p> Signup and view all the answers

    Match the following adverse effects with their categories:

    <p>Tremors = CNS Increased HR = CV Leg cramps = CNS Dyspnea = OTHER</p> Signup and view all the answers

    Study Notes

    Dobutamine Overview

    • Dobutamine is classified as a sympathomimetic agent utilized primarily in cardiac conditions.
    • Marketed under the trade name Dobutrex.

    Mechanism of Action

    • Enhances cardiac output through positive inotropic effects.
    • Decreases pulmonary wedge pressure by stimulating myocardial beta and alpha adrenergic receptors.

    Clinical Uses

    • Indicated for increasing cardiac output in patients with congestive heart failure (CHF) or cardiogenic shock.

    Dosage Guidelines

    • Adult administration ranges from 2 to 20 mcg/kg/min, adjusted according to the desired therapeutic effect.
    • Pediatric dosing mirrors adult guidelines, set between 2 to 20 mcg/kg/min, also tailored to effect.

    Contraindications

    • Should not be used in individuals with hypersensitivity to sympathomimetic amines.
    • Avoid in patients with ventricular tachycardia (V-Tach) and idiopathic hypertrophic subaortic stenosis.

    Adverse Effects

    • Central Nervous System: Possible side effects include tremors, paresthesia, leg cramps, and nervousness.
    • Cardiovascular: May cause increased heart rate and blood pressure, premature ventricular contractions (PVCs), palpitations, and angina.
    • Respiratory: Potential dyspnea experienced by some patients.

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    Description

    Test your knowledge on Dobutamine with these informative flashcards. Discover its uses, mechanism of action, and trade names. Perfect for medical students or healthcare professionals looking to refresh their understanding of this sympathomimetic agent.

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