DNA Viruses: Properties of Parvoviruses
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Questions and Answers

What is the size of the Parvovirus B19?

  • 20 nm
  • 22 nm (correct)
  • 25 nm
  • 30 nm

What is the mode of transmission of Parvovirus B19?

  • Only through respiratory route
  • Only through blood transfusion
  • Through respiratory route, blood transfusion, and vertically from mother to fetus (correct)
  • Only through vertically from mother to fetus

What is the disease caused by Parvovirus B19 in children?

  • Scarlet fever
  • Erythema infectiosum (Slapped Cheek syndrome, Fifth disease) (correct)
  • Roseola
  • Rubella

What is the effect of Parvovirus B19 infection in immunodeficient patients?

<p>Chronic suppression of the bone marrow and chronic anemia (D)</p> Signup and view all the answers

What is the consequence of fetal infection with Parvovirus B19?

<p>Both congenital malformations and fetal death due to severe anemia (C)</p> Signup and view all the answers

What is the serotype of Parvovirus B19?

<p>One serotype (D)</p> Signup and view all the answers

What is the primary cell type infected by B19 virus in the bone marrow?

<p>Erythroblasts (D)</p> Signup and view all the answers

What contributes to the pathogenesis of the rash associated with erythema infectiosum?

<p>Immune complexes composed of virus and IgM or IgG (B)</p> Signup and view all the answers

What is the outcome of infection with B19 virus?

<p>Lifelong immunity against reinfection (C)</p> Signup and view all the answers

What is the characteristic manifestation of hydrops fetalis?

<p>Massive edema of the fetus (A)</p> Signup and view all the answers

What is the purpose of commercial immunoglobulin preparations in B19 virus infection?

<p>To contain neutralizing antibodies for immunodeficient patients and anemic (B)</p> Signup and view all the answers

What is the current status of vaccination against human parvovirus?

<p>There is no vaccine against human parvovirus (C)</p> Signup and view all the answers

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