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DNA Viruses: Properties of Parvoviruses

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Questions and Answers

What is the size of the Parvovirus B19?

20 nm

22 nm (correct)

25 nm

30 nm

What is the mode of transmission of Parvovirus B19?

Only through respiratory route

Only through blood transfusion

Through respiratory route, blood transfusion, and vertically from mother to fetus (correct)

Only through vertically from mother to fetus

What is the disease caused by Parvovirus B19 in children?

Scarlet fever

Erythema infectiosum (Slapped Cheek syndrome, Fifth disease) (correct)

Roseola

Rubella

What is the effect of Parvovirus B19 infection in immunodeficient patients?

Chronic suppression of the bone marrow and chronic anemia Signup and view all the answers

What is the consequence of fetal infection with Parvovirus B19?

Both congenital malformations and fetal death due to severe anemia Signup and view all the answers

What is the serotype of Parvovirus B19?

One serotype Signup and view all the answers

What is the primary cell type infected by B19 virus in the bone marrow?

Erythroblasts Signup and view all the answers

What contributes to the pathogenesis of the rash associated with erythema infectiosum?

Immune complexes composed of virus and IgM or IgG Signup and view all the answers

What is the outcome of infection with B19 virus?

Lifelong immunity against reinfection Signup and view all the answers

What is the characteristic manifestation of hydrops fetalis?

Massive edema of the fetus Signup and view all the answers

What is the purpose of commercial immunoglobulin preparations in B19 virus infection?

To contain neutralizing antibodies for immunodeficient patients and anemic Signup and view all the answers

What is the current status of vaccination against human parvovirus?

There is no vaccine against human parvovirus Signup and view all the answers