12 Questions
What is the size of the Parvovirus B19?
22 nm
What is the mode of transmission of Parvovirus B19?
Through respiratory route, blood transfusion, and vertically from mother to fetus
What is the disease caused by Parvovirus B19 in children?
Erythema infectiosum (Slapped Cheek syndrome, Fifth disease)
What is the effect of Parvovirus B19 infection in immunodeficient patients?
Chronic suppression of the bone marrow and chronic anemia
What is the consequence of fetal infection with Parvovirus B19?
Both congenital malformations and fetal death due to severe anemia
What is the serotype of Parvovirus B19?
One serotype
What is the primary cell type infected by B19 virus in the bone marrow?
Erythroblasts
What contributes to the pathogenesis of the rash associated with erythema infectiosum?
Immune complexes composed of virus and IgM or IgG
What is the outcome of infection with B19 virus?
Lifelong immunity against reinfection
What is the characteristic manifestation of hydrops fetalis?
Massive edema of the fetus
What is the purpose of commercial immunoglobulin preparations in B19 virus infection?
To contain neutralizing antibodies for immunodeficient patients and anemic
What is the current status of vaccination against human parvovirus?
There is no vaccine against human parvovirus
This quiz covers the properties and characteristics of parvoviruses, including their transmission routes and genome structure. Learn about the medically important DNA viruses and their classification.
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