DNA Structure
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Questions and Answers

Which of these nitrogenous bases pairs with adenine (A) in DNA?

  • Guanine (G)
  • Thymine (T) (correct)
  • Cytosine (C)
  • Uracil (U)
  • DNA replication results in two identical DNA molecules, each with one original strand and one newly synthesized strand.

    True (A)

    What is the name of the sugar molecule found in DNA?

    Deoxyribose

    The two strands of the DNA double helix run in opposite directions, a property known as ______.

    <p>antiparallel</p> Signup and view all the answers

    Match the following components of DNA with their corresponding descriptions.

    <p>Deoxyribose = A five-carbon sugar Phosphate = A negatively charged group Adenine, Thymine, Guanine, Cytosine = Nitrogenous bases that form the rungs of the DNA ladder Hydrogen bonds = Hold the base pairs together Double helix = The twisted ladder shape of DNA</p> Signup and view all the answers

    The two strands of the DNA double helix are parallel to each other.

    <p>False (B)</p> Signup and view all the answers

    Which of these nitrogenous bases does NOT pair with adenine (A) in DNA?

    <p>Cytosine (C) (B), Uracil (U) (C), Guanine (G) (D)</p> Signup and view all the answers

    What is the name of the process by which a DNA molecule creates an exact copy of itself?

    <p>DNA replication</p> Signup and view all the answers

    The sugar in DNA is called ______.

    <p>deoxyribose</p> Signup and view all the answers

    What type of bond holds the nitrogenous bases together in the DNA double helix?

    <p>Hydrogen bonds (C)</p> Signup and view all the answers

    Match the following components of DNA with their descriptions:

    <p>Adenine = Nitrogenous base that pairs with thymine Deoxyribose = Sugar molecule found in DNA Phosphate group = Connects deoxyribose sugars together Cytosine = Nitrogenous base that pairs with guanine Thymine = Nitrogenous base that pairs with adenine</p> Signup and view all the answers

    What is the significance of the specific base pairing rules in DNA?

    <p>The specific base pairing rules (A-T and G-C) ensure that the DNA strands are complementary, which is crucial for accurate replication and the preservation of genetic information.</p> Signup and view all the answers

    The two strands of the DNA double helix run in opposite directions, this is known as ______.

    <p>antiparallel</p> Signup and view all the answers

    Mismatches in base pairing during DNA replication are always corrected and never lead to mutations.

    <p>False (B)</p> Signup and view all the answers

    Why is the DNA double helix described as a twisted ladder?

    <p>The two antiparallel strands of DNA are linked by pairs of nitrogenous bases, which form the 'rungs' of the ladder. These rungs are connected by a sugar-phosphate backbone, forming the 'sides' of the ladder.</p> Signup and view all the answers

    What are molecules?

    <p>Molecules are groups of two or more atoms bonded together.</p> Signup and view all the answers

    Flashcards

    DNA

    Deoxyribonucleic acid, a molecule carrying genetic instructions.

    Double Helix

    The twisted ladder structure of DNA allowing efficient storage of genetic information.

    Sugar-Phosphate Backbone

    The alternating chain of sugar and phosphate that forms the sides of DNA.

    Base Pairing

    Specific pairing of nitrogenous bases A-T and G-C crucial for DNA stability.

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    Antiparallel Strands

    Two DNA strands running in opposite directions.

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    Major and Minor Grooves

    Grooves in the DNA structure important for protein interaction with DNA.

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    DNA Replication

    Process of making an identical copy of DNA before cell division.

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    Hydrogen Bonds

    Weak bonds that hold together the base pairs in DNA.

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    Sequence of Bases

    The order of nitrogenous bases that dictates genetic information.

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    Genetic Instructions

    Information encoded in DNA that guides organism development and functioning.

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    Nitrogenous Bases

    The building blocks of DNA; A, T, G, and C.

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    Adenine

    A nitrogenous base that always pairs with thymine in DNA.

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    Thymine

    A nitrogenous base that always pairs with adenine in DNA.

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    Guanine

    A nitrogenous base that always pairs with cytosine in DNA.

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    Cytosine

    A nitrogenous base that always pairs with guanine in DNA.

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    DNA Replication Enzymes

    Proteins that help unzip DNA and add new bases during replication.

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    DNA Strand Separation

    The process of unwinding DNA for copying or transcription.

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    Complementary Strands

    Strands of DNA that match according to base pairing rules.

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    Mutation

    A change in DNA sequence that can affect protein function.

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    Genetic Information Preservation

    The process by which the integrity of DNA is maintained during replication.

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    Study Notes

    DNA Structure

    • DNA, or deoxyribonucleic acid, is a complex molecule carrying the genetic instructions for all living organisms.
    • The fundamental structure is a double helix, resembling a twisted ladder.
    • The "sides" consist of alternating sugar (deoxyribose) and phosphate molecules forming a sugar-phosphate backbone.
    • The "rungs" are formed by pairs of nitrogenous bases: adenine (A), thymine (T), guanine (G), and cytosine (C).
    • Adenine always pairs with thymine (A-T), and guanine always pairs with cytosine (G-C).
    • Hydrogen bonds hold these base pairs together.
    • The sequence of these bases dictates the genetic information, determining an organism's traits.

    Key Features of DNA Structure

    • Double Helix: The DNA molecule's shape, a twisted ladder, efficiently stores genetic information and facilitates replication.
    • Antiparallel Strands: The two DNA strands run in opposite directions (antiparallel). This arrangement is crucial for replication and repair processes.
    • Major and Minor Grooves: The double helix has two grooves, major and minor, important for protein interactions.
    • Base Pairing: Precise pairing (A-T and G-C) is critical for DNA stability and replication; replication ensures accurate base sequence duplication. Mismatched pairs can lead to mutations. This precise pairing is vital for the integrity of the genetic code.
    • Sugar-Phosphate Backbone: The alternating sugar and phosphate molecules form the DNA backbone, providing structure and polarity. The sugar in DNA is deoxyribose. Phosphate groups link the deoxyribose sugars, forming a strong, stable structure.

    Importance of DNA Structure

    • The DNA base sequence determines building instructions and organism maintenance.
    • The double helix enables accurate DNA replication during cell division.
    • The antiparallel strands guide replication and repair enzymes.
    • Base pairing preserves genetic information, preventing mutations from incorrect base associations.
    • DNA grooves allow expression-regulating proteins to bind and control gene activity.

    DNA Replication

    • DNA replication is the cell's process of copying DNA, ensuring each daughter cell receives an identical set of genetic instructions.
    • Semiconservative Replication - Each new DNA molecule contains one original strand and one newly synthesized strand.
    • Helicases unwind the DNA double helix.
    • Primase synthesizes RNA primers for DNA polymerase initiation.
    • DNA polymerase adds complementary nucleotides to growing strands.
    • DNA ligase joins lagging strand fragments. This process depends on the antiparallel structure and specific base pairing.

    Additional Information

    • Hydrogen Bonds: Weak hydrogen bonds between base pairs hold the two strands together, enabling strand separation during processes like replication and transcription. The specific pairing (A-T and G-C) contributes to the stability and accuracy of the DNA helix.
    • DNA vs. RNA: DNA and RNA are nucleic acids, but DNA is a double-stranded helix, while RNA is typically single-stranded. RNA contains uracil (U) instead of thymine (T). DNA stores genetic information, and RNA plays a role in protein synthesis.
    • Base Pairing Importance: The specific pairing (A-T and G-C) is vital for maintaining the continuity of the genetic code, allowing for precise replication and preserving the integrity of the genetic information. Mismatches can lead to mutations affecting protein function and potentially causing diseases.
    • Functional implications of structure: The specific base pairings, the double helix structure, and the sugar-phosphate backbone are vital for DNA's function in carrying and transmitting genetic information. The compact storage of genetic information facilitated by the double helix structure is essential for replication and gene expression.

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    Description

    Explore the intricate structure of DNA, the molecule that carries genetic instructions in all living organisms. This quiz covers the double helix formation, base pairing rules, and the significance of DNA structure in genetics.

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