12 Questions
What type of DNA replication involves one old and one newly made strand in the replicated double helix?
Semiconservative model
What is the role of helicases in DNA replication?
Unwinding the double helix
Which enzyme synthesizes RNA primers during DNA replication?
Primase
In what direction does DNA polymerase elongate the new DNA strand?
5' to 3'
What is the function of single-strand binding proteins in DNA replication?
Stabilizing unwound DNA strands
Which molecule released during nucleotide addition helps drive the polymerization reaction during DNA replication?
Pyrophosphate
What is the primary difference between the synthesis of the leading and lagging strands during DNA replication?
The leading strand is synthesized continuously, while the lagging strand is synthesized discontinuously.
What is the function of DNA ligase in DNA replication?
To join the sugar-phosphate backbones of Okazaki fragments into a continuous DNA strand.
Why does DNA replication only proceed in the 5′→3′ direction?
As a result of the physical and chemical structure of nucleotides.
When does DNA polymerase I replace RNA nucleotides with DNA nucleotides?
After each Okazaki fragment is synthesized.
Which enzyme plays a key role in reducing the error rate during DNA replication?
Mismatch repair enzymes
Why is lagging strand synthesis slightly delayed relative to leading strand synthesis?
As a result of the series of short Okazaki fragments being primed separately.
Learn about the semiconservative model of DNA replication proposed by Watson and Crick, where each daughter molecule has one old and one new strand. Explore the complex biochemical process of DNA replication, which is highly accurate and rapid, involving many enzymes and proteins.
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