DNA Replication Process Overview
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Questions and Answers

What is the enzymatic activity of helicases during DNA replication?

  • Forming RNA primers
  • Polymerizing nucleotides
  • Relieving tensions created by the replication bubble
  • Unwinding the parental DNA strands (correct)

Which complex prevents the whole DNA polymerase ε complex from falling off the template during DNA replication?

  • RPA
  • RFC
  • PCNA (correct)
  • Primase

What is the function of DNA ligases in the process of DNA replication?

  • Unwinding the parental DNA strands
  • Protecting single-strand DNA from nucleases
  • Polymerizing nucleotides
  • Ligating the different strands being formed (correct)

Which enzyme is responsible for adding deoxynucleotides to the free hydroxyl group at the 3′ end of the primer during DNA replication?

<p>DNA polymerase (D)</p> Signup and view all the answers

What is the main function of primases in DNA replication?

<p>Forming RNA primers (A)</p> Signup and view all the answers

What type of replication is observed in DNA replication?

<p>Semi-continuous in one strand (D)</p> Signup and view all the answers

What is the function of the clamp loader in DNA replication?

<p>Opens the PCNA ring to load onto DNA (D)</p> Signup and view all the answers

Which enzyme is responsible for synthesizing short RNA primers in DNA replication?

<p>RNA primase (D)</p> Signup and view all the answers

What is the function of DNA polymerase-alpha in DNA replication?

<p>Adds DNA to the RNA primer (C)</p> Signup and view all the answers

What is the main function of DNA ligases in DNA replication?

<p>Joining Okazaki fragments together (C)</p> Signup and view all the answers

Which part of a chromosome makes up the G-tail at the 3'-end?

<p>Terminal portion of the G-rich strand (A)</p> Signup and view all the answers

What is a common feature of all telomeres?

<p>Single-stranded G-tail (B)</p> Signup and view all the answers

Which direction does DNA synthesis always proceed during replication?

<p>5' -&gt; 3' (A)</p> Signup and view all the answers

Which enzyme is responsible for the formation of Okazaki fragments?

<p>Primase (D)</p> Signup and view all the answers

What is the function of DNA ligase in DNA replication?

<p>Sealing nicks in the sugar-phosphate backbone (D)</p> Signup and view all the answers

During DNA replication, which enzyme is responsible for unwinding the DNA double helix?

<p>Helicase (D)</p> Signup and view all the answers

What is the role of DNA polymerase III in DNA replication?

<p>Main enzyme for leading strand synthesis (A)</p> Signup and view all the answers

In DNA replication, which enzyme is required to join Okazaki fragments together?

<p>DNA ligase (B)</p> Signup and view all the answers

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