DNA Replication Process

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<p>A single origin rich in A and T bases. (A)</p> Signup and view all the answers

<p>It breaks hydrogen bonds to separate DNA strands. (A)</p> Signup and view all the answers

Areas on bacterial DNA rich in adenine (A) and thymine (T) bases where DNA replication starts.

The enzyme that initiates the separation of DNA strands at the origin of replication.

The open section of DNA formed when the strands are separated. It looks like a bubble.

Proteins that bind to single strands of DNA to prevent them from reannealing.

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An enzyme that unwinds the DNA helix ahead of the replication fork, requiring significant energy to break hydrogen bonds.

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Replication starts by separating DNA strands at several locations. These locations are rich in adenine (A) and thymine (T) bases.
Bacterial DNA has only one origin point.
The enzyme that initially separates DNA strands at the origin point is called DNA-A protein.
Once the area is open (unzipped), it's called a replication bubble.
Single-strand binding proteins (SSB proteins) stabilize the replication bubble by preventing the separated DNA strands from rejoining (reannealing).
SSB proteins also protect single strands of DNA from being damaged.
The enzyme helicase unwinds the DNA double helix further.
Helicase requires a lot of energy to break the hydrogen bonds between bases.
As helicase moves along, it creates supercoils in the DNA ahead of it.
To remove supercoils, enzymes are needed. (This section is incomplete)