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Transcription
Transcription
The process by which genetic information in DNA is copied into messenger RNA (mRNA) for protein synthesis.
Excision Repair
Excision Repair
A mechanism that removes and replaces damaged DNA, such as nucleotide excision repair, which corrects UV-induced damage.
Translation
Translation
The process by which ribosomes convert the genetic information in mRNA into a sequence of amino acids to build proteins.
Mismatch Repair
Mismatch Repair
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Codon
Codon
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PCR (Polymerase Chain Reaction)
PCR (Polymerase Chain Reaction)
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Aminoacyl-tRNA Synthetase
Aminoacyl-tRNA Synthetase
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Sanger Sequencing
Sanger Sequencing
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Genetic Code
Genetic Code
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DNA Polymerase
DNA Polymerase
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Anticodon
Anticodon
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Proofreading
Proofreading
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Silent Mutation
Silent Mutation
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Introns
Introns
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tRNA (Transfer RNA)
tRNA (Transfer RNA)
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Rosalind Franklin
Rosalind Franklin
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Okazaki fragment
Okazaki fragment
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Watson and Crick
Watson and Crick
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ORI (Origin of Replication)
ORI (Origin of Replication)
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Transformation
Transformation
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Leading Strand
Leading Strand
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Chargaff
Chargaff
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Telomerase
Telomerase
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Helicase
Helicase
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Lagging Strand
Lagging Strand
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Template
Template
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Plasmid
Plasmid
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Antiparallel
Antiparallel
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Semi-conservative
Semi-conservative
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Primer
Primer
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Study Notes
DNA Replication and Repair
- Transcription: Copies genetic information from DNA into messenger RNA (mRNA) for protein production.
- Excision Repair: Removes and replaces damaged DNA, like UV-induced damage.
- Translation: Ribosomes convert mRNA into amino acid sequences forming proteins.
- Mismatch Repair: Fixes errors in DNA replication, like insertion, deletion, and mis-incorporation of bases.
- Codon: Three nucleotides in mRNA that code for an amino acid or stop signal.
- PCR (Polymerase Chain Reaction): Creates multiple copies of a DNA segment.
- Aminoacyl-tRNA Synthetase: Attaches the right amino acid to its tRNA.
- Sanger Sequencing: Method of DNA sequencing using chain-terminating dideoxynucleotides.
- Genetic Code: Rules for translating mRNA sequences into proteins.
- DNA Polymerase: Enzyme synthesizing DNA from deoxyribonucleotides (essential for replication).
- Anticodon: tRNA sequence complementary to a codon in mRNA.
- Proofreading: DNA polymerase's error-correction mechanism; removes incorrect nucleotides.
- Silent Mutation: Nucleotide change with no effect on the amino acid sequence.
- Introns: Non-coding DNA sequences removed from RNA during processing.
- tRNA (Transfer RNA): Carries amino acids to the ribosome during translation.
- Rosalind Franklin: Her X-ray diffraction images helped discover the double helix.
- Okazaki Fragment: Short DNA segments synthesized discontinuously on the lagging strand.
- Watson and Crick: Discovered the double helix structure of DNA, drawing on Rosalind Franklin's data.
- ORI (Origin of Replication): DNA sequence where replication starts.
- Transformation: Acquiring exogenous genetic material from surrounding environment.
- Leading Strand: DNA strand synthesized continuously during replication.
DNA Structure and Function
- Chargaff's Rules: DNA from any cell has a 1:1 ratio of A=T and C=G.
- Telomerase: Adds nucleotides to chromosome ends to prevent shortening.
- Helicase: Enzyme unwinding the DNA helix during replication.
- Lagging Strand: Synthesized discontinuously in short sections (Okazaki fragments).
- Template: DNA or RNA strand used as a guide for complementary strand synthesis.
- Plasmid: Small, circular, double-stranded DNA molecules.
- Antiparallel: Opposite 5' to 3' orientations of DNA strands in the double helix.
- Semi-conservative: In DNA replication, each new double helix contains one old and one new strand.
- Primer: Short nucleic acid sequence starting DNA synthesis.
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