5 Questions
What is the frequency of mismatched bases incorporated into new DNA during the process of replication?
About 10−4 to 10−5
What is the main role of mismatch-repair enzymes in DNA replication?
To cut out a section of the newly synthesized strand and fill the gap with new nucleotides
How are incorrectly paired bases detected and corrected in DNA?
By mismatch-repair enzymes
What must mismatch repair have in order to work effectively?
A way to distinguish between old and new strands of DNA
What is the purpose of filling the gap with new nucleotides in DNA replication?
To maintain the integrity of the DNA sequence
Test your knowledge on the accuracy of DNA replication and the mechanisms that prevent permanent mutations. Learn about the frequency of mismatched bases and the role of DNA polymerases in proofreading.
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