Lect. 6
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Questions and Answers

What is the function of Replicative recombination?

  • Separates advantageous traits and important gene combinations in offspring
  • Clears nonfunctional alleles from a population
  • Generates a new copy of a DNA segment (correct)
  • Catalyzes specific enzyme recognition in the target site
  • What can be detected using the Recombination Detection Program (RDP)?

  • Recombination (correct)
  • Genetic mutations
  • Population dynamics
  • Allele combinations
  • Recombination of DNA always requires specific enzymatic machinery for each particular site.

    False

    Recombination allows nonfunctional alleles to be preserved in a population.

    <p>False</p> Signup and view all the answers

    Advantages of genetic recombination include separation of alleles over time.

    <p>False</p> Signup and view all the answers

    Without recombination, a deleterious mutant allele would cause an entire chromosome to be eliminated from the population.

    <p>True</p> Signup and view all the answers

    Replicative recombination is catalyzed by a specific enzyme that recognizes a short sequence present in the target site in the bacterial chromosome.

    <p>True</p> Signup and view all the answers

    Recombination can only occur at the DNA level for viruses.

    <p>False</p> Signup and view all the answers

    Recombination by independent assortment can occur among viruses with non-segmented genomes.

    <p>False</p> Signup and view all the answers

    Homologous recombination occurs between DNA with extensive sequence homology anywhere within the homology.

    <p>True</p> Signup and view all the answers

    Site-specific recombination occurs between DNA with extensive sequence homology.

    <p>False</p> Signup and view all the answers

    Recombination leads to the generation of viruses with new antigenic determinants through dependent assortment.

    <p>False</p> Signup and view all the answers

    What is the outcome of genetic recombination in viruses?

    <p>A new genetic entity with non-parental genetic combinations</p> Signup and view all the answers

    What is the difference between homologous and site-specific recombination?

    <p>Homologous recombination occurs between DNA with extensive sequence homology, while site-specific recombination occurs between DNA with no extensive homology</p> Signup and view all the answers

    What type of recombination can lead to the generation of viruses with new antigenic determinants and new host ranges?

    <p>Recombination by independent assortment</p> Signup and view all the answers

    Study Notes

    Recombination of DNA: Types and Examples

    • Gene C is now located on the same chromosome as genes D and E
    • Two types of recombination: Homologous recombination and nonhomologous recombination
    • Site-specific recombination occurs between particular short sequences present on dissimilar parental molecules
    • Site-specific recombination requires specific enzymatic machinery for each particular site
    • Replicative recombination generates a new copy of a DNA segment
    • Recombination can be detected using the Recombination Detection Program (RDP)
    • Advantages of genetic recombination include DNA homogenization, new allele combinations, and separation of alleles over time
    • Disadvantages of genetic recombination include separation of advantageous traits and important gene combinations in offspring
    • Recombination allows nonfunctional alleles to be cleared from a population and rare beneficial alleles to be tested
    • Without recombination, a deleterious mutant allele would cause an entire chromosome to be eliminated from the population
    • Recombinational events can be detected in natural populations, such as a recombinant dengue virus type 1 with three recombination regions in Guangdong province, China
    • Replicative recombination is catalyzed by a specific enzyme that recognizes a short sequence present in the target site in the bacterial chromosome.

    Recombination of DNA: Types and Examples

    • Gene C is now located on the same chromosome as genes D and E
    • Two types of recombination: Homologous recombination and nonhomologous recombination
    • Site-specific recombination occurs between particular short sequences present on dissimilar parental molecules
    • Site-specific recombination requires specific enzymatic machinery for each particular site
    • Replicative recombination generates a new copy of a DNA segment
    • Recombination can be detected using the Recombination Detection Program (RDP)
    • Advantages of genetic recombination include DNA homogenization, new allele combinations, and separation of alleles over time
    • Disadvantages of genetic recombination include separation of advantageous traits and important gene combinations in offspring
    • Recombination allows nonfunctional alleles to be cleared from a population and rare beneficial alleles to be tested
    • Without recombination, a deleterious mutant allele would cause an entire chromosome to be eliminated from the population
    • Recombinational events can be detected in natural populations, such as a recombinant dengue virus type 1 with three recombination regions in Guangdong province, China
    • Replicative recombination is catalyzed by a specific enzyme that recognizes a short sequence present in the target site in the bacterial chromosome.

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    Description

    Test your knowledge of DNA recombination with this quiz covering types, examples, and the impact of genetic recombination on populations. Explore concepts such as homologous recombination, site-specific recombination, replicative recombination, and the advantages and disadvantages of genetic recombination.

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