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Questions and Answers
Which type of mutation causes sickle cell anemia?
Which type of mutation causes sickle cell anemia?
- Missense (correct)
- Nonsense
- Frameshift
- Silent
Based on scientific research, which statement best describes mutations?
Based on scientific research, which statement best describes mutations?
Mutations are rare occurrences.
Ji wants to write an example of a frameshift mutation using the following sentence: THE CAT SAW THE RAT. Which sentence best shows a frameshift mutation?
Ji wants to write an example of a frameshift mutation using the following sentence: THE CAT SAW THE RAT. Which sentence best shows a frameshift mutation?
THC ATS AWT HER AT.
Which type of mutation occurs only in gametes?
Which type of mutation occurs only in gametes?
Which statement best provides evidence that the substance is a mutagen?
Which statement best provides evidence that the substance is a mutagen?
Which type of mutation always produces a stop codon?
Which type of mutation always produces a stop codon?
Which is a point mutation and not a frameshift mutation?
Which is a point mutation and not a frameshift mutation?
Which best describes somatic mutations?
Which best describes somatic mutations?
A mutagen is
A mutagen is
Which type of mutation occurs only in reproductive cells?
Which type of mutation occurs only in reproductive cells?
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Study Notes
DNA Mutations Overview
- Sickle cell anemia is caused by a missense mutation, which results in a single amino acid substitution in the hemoglobin protein.
- Mutations are considered rare occurrences in the genetic makeup of organisms.
Types of Mutations
- A frameshift mutation alters the reading frame of the genetic code, exemplified by changing "THE CAT SAW THE RAT" to "THC ATS AWT HER AT".
- Germline mutations occur specifically in gametes, affecting future generations.
- A nonsense mutation produces a stop codon, potentially leading to truncated protein synthesis.
- Point mutations involve a single nucleotide change, such as substitutions, and are not classified as frameshift mutations.
- Somatic mutations arise in non-reproductive cells and can lead to various types of cancer.
Mutagens and Cellular Change
- A substance is classified as a mutagen if it can induce mutations, evidenced by observable changes in cells that are inherited by subsequent generations.
- Germline mutations specifically affect reproductive cells and can be passed on to offspring, contrasting with somatic mutations which do not affect inheritance.
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