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Questions and Answers
What is the main purpose of DNA replication in cells?
What is the main purpose of DNA replication in cells?
What enzyme is responsible for breaking the hydrogen bonds in DNA during replication?
What enzyme is responsible for breaking the hydrogen bonds in DNA during replication?
What characterizes semi-conservative replication?
What characterizes semi-conservative replication?
What is the process called that transforms RNA into proteins?
What is the process called that transforms RNA into proteins?
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How does DNA get the instructions to the ribosomes?
How does DNA get the instructions to the ribosomes?
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What does the Central Dogma of molecular biology describe?
What does the Central Dogma of molecular biology describe?
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What significant measurement is true regarding human DNA in cells?
What significant measurement is true regarding human DNA in cells?
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What role do DNA polymerases play during DNA replication?
What role do DNA polymerases play during DNA replication?
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What are nucleotides composed of?
What are nucleotides composed of?
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What type of bond forms between the sugar and the phosphoryl group in a nucleotide?
What type of bond forms between the sugar and the phosphoryl group in a nucleotide?
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Which nitrogenous bases are classified as purines?
Which nitrogenous bases are classified as purines?
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How many rings make up the structure of purines?
How many rings make up the structure of purines?
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What type of linkage occurs between the base and the sugar in a nucleotide?
What type of linkage occurs between the base and the sugar in a nucleotide?
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What is the structure of pyrimidines?
What is the structure of pyrimidines?
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Which of the following represents the sugar found in DNA nucleotides?
Which of the following represents the sugar found in DNA nucleotides?
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What structural formation do two DNA strands create?
What structural formation do two DNA strands create?
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What is the primary function of DNA in cells?
What is the primary function of DNA in cells?
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What are the building blocks of DNA and RNA?
What are the building blocks of DNA and RNA?
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Which of the following is a trait determined by genetic information?
Which of the following is a trait determined by genetic information?
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Which sugar is found in DNA?
Which sugar is found in DNA?
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Which scientist is NOT associated with the discovery of the DNA double helix structure?
Which scientist is NOT associated with the discovery of the DNA double helix structure?
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What role do proteins play in the body?
What role do proteins play in the body?
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Why is the study of DNA considered important?
Why is the study of DNA considered important?
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What is the role of alleles in genetics?
What is the role of alleles in genetics?
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What type of bond holds the rungs of the DNA ladder together?
What type of bond holds the rungs of the DNA ladder together?
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Which base pairs with adenine in DNA according to the base pair rule?
Which base pairs with adenine in DNA according to the base pair rule?
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What is the diameter of the DNA double helix?
What is the diameter of the DNA double helix?
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In what direction do the two DNA strands run?
In what direction do the two DNA strands run?
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What is the role of nucleosomes in eukaryotic chromosomes?
What is the role of nucleosomes in eukaryotic chromosomes?
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What unique feature does RNA possess compared to DNA?
What unique feature does RNA possess compared to DNA?
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What is the main purpose of DNA replication?
What is the main purpose of DNA replication?
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Which nitrogenous base pairs with cytosine in DNA?
Which nitrogenous base pairs with cytosine in DNA?
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Which feature is characteristic of prokaryotic chromosomes?
Which feature is characteristic of prokaryotic chromosomes?
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What type of bonding occurs between uracil and adenine in RNA?
What type of bonding occurs between uracil and adenine in RNA?
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What is the primary advantage of semi-conservative replication in DNA?
What is the primary advantage of semi-conservative replication in DNA?
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Which process directly involves the usage of messenger RNA (mRNA) to construct proteins?
Which process directly involves the usage of messenger RNA (mRNA) to construct proteins?
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Which component of the DNA replication process is responsible for adding nucleotides to the growing DNA strand?
Which component of the DNA replication process is responsible for adding nucleotides to the growing DNA strand?
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In which location does transcription occur within a eukaryotic cell?
In which location does transcription occur within a eukaryotic cell?
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Which of the following best describes the role of DNA helicases during replication?
Which of the following best describes the role of DNA helicases during replication?
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What is the approximate total length of DNA present in an average human?
What is the approximate total length of DNA present in an average human?
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How does the central dogma describe the flow of genetic information?
How does the central dogma describe the flow of genetic information?
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What is the function of the newly synthesized strand in the semi-conservative replication model?
What is the function of the newly synthesized strand in the semi-conservative replication model?
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What is the overall structure of DNA characterized by?
What is the overall structure of DNA characterized by?
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What type of bond links the nitrogenous base to the sugar in a nucleotide?
What type of bond links the nitrogenous base to the sugar in a nucleotide?
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Which of the following correctly describes the structural formation of purines?
Which of the following correctly describes the structural formation of purines?
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What is the primary role of proteins in biological systems?
What is the primary role of proteins in biological systems?
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Identify the component that forms the phosphoester bond in nucleotides.
Identify the component that forms the phosphoester bond in nucleotides.
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Which statement accurately describes the nature of genes?
Which statement accurately describes the nature of genes?
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What structural characteristic differentiates pyrimidines from purines?
What structural characteristic differentiates pyrimidines from purines?
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Why was Rosalind Franklin significant in the discovery of DNA structure?
Why was Rosalind Franklin significant in the discovery of DNA structure?
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What is the primary role of the nitrogenous bases in DNA?
What is the primary role of the nitrogenous bases in DNA?
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Which two bases are classified as pyrimidines in DNA?
Which two bases are classified as pyrimidines in DNA?
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In the context of DNA structure, what is meant by the term 'nucleotide'?
In the context of DNA structure, what is meant by the term 'nucleotide'?
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Which aspect of DNA is most closely related to its function as the blueprint of life?
Which aspect of DNA is most closely related to its function as the blueprint of life?
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How are the sugar ring numbers designated in nucleotide structures?
How are the sugar ring numbers designated in nucleotide structures?
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What is the significance of dominant and recessive alleles in determining traits?
What is the significance of dominant and recessive alleles in determining traits?
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Which component is NOT part of a nucleotide structure?
Which component is NOT part of a nucleotide structure?
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How do the roles of DNA and RNA differ in biological organisms?
How do the roles of DNA and RNA differ in biological organisms?
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What type of bonds are primarily responsible for maintaining the double helical structure of DNA?
What type of bonds are primarily responsible for maintaining the double helical structure of DNA?
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Which correct base pairing occurs in DNA according to the base pair rule?
Which correct base pairing occurs in DNA according to the base pair rule?
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How do the two strands of DNA relate to each other?
How do the two strands of DNA relate to each other?
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In eukaryotic chromosomes, the structure that consists of DNA wrapped around histone proteins is known as what?
In eukaryotic chromosomes, the structure that consists of DNA wrapped around histone proteins is known as what?
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What does the term 'supercoiled' refer to in the context of prokaryotic chromosomes?
What does the term 'supercoiled' refer to in the context of prokaryotic chromosomes?
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Which of the following statements about RNA is correct?
Which of the following statements about RNA is correct?
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What advantage does the presence of hydrogen bonds provide in DNA's structure?
What advantage does the presence of hydrogen bonds provide in DNA's structure?
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How many nucleotides are present in one complete turn of the DNA double helix?
How many nucleotides are present in one complete turn of the DNA double helix?
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What property of DNA is described by the term 'complementary strands'?
What property of DNA is described by the term 'complementary strands'?
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What structural feature is characteristic of eukaryotic chromosomes compared to prokaryotic chromosomes?
What structural feature is characteristic of eukaryotic chromosomes compared to prokaryotic chromosomes?
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Study Notes
DNA and RNA Structure
- Genetics is the study of genes and heredity.
- A trait is an inherited characteristic determined by the presence and expression of dominant and/or recessive alleles.
- A gene is a segment of DNA that codes for a protein which in turn codes for a trait.
- Chromosomes are made up of DNA.
- Deoxyribonucleic acid (DNA) stores genetic information.
- DNA is a blueprint of life that contains instructions for making proteins within a cell.
- Proteins are responsible for all cell structures and functions and are made up of long chains of amino acids.
- DNA carries genetic information from parents to offspring.
- DNA is essential for all life on Earth.
- DNA is important for medical benefits in disease detection, treatment, and prevention.
- DNA is important in the development of crops.
- DNA is important in forensics.
- DNA and RNA are long polymers with monomer units called nucleotides.
- A nucleotide consists of a nitrogen containing heterocyclic base (purine or pyrimidine), a five carbon sugar ring (ribose or deoxyribose), and a phosphoryl group.
- DNA is a polymer with two long strands, each a chain of nucleotides.
- A nucleotide contains a phosphate, a 5 carbon sugar (deoxyribose), and a nitrogenous base.
- Adenine and guanine are purines made up of two rings of carbon and nitrogen atoms.
- Thymine and cytosine are pyrimidines made up of a single 6-membered ring of carbon and nitrogen.
- Adenine bonds with thymine (2 hydrogen bonds).
- Cytosine bonds with guanine (3 hydrogen bonds).
- The base pairing rule states that adenine can only bond with thymine and cytosine can only bond with guanine.
- The two strands of DNA twist around a central axis to form a double helix.
- Sides of the DNA strand alternate phosphate and sugar (deoxyribose).
- Rungs of DNA are held together by hydrogen bonds.
- The two strands of DNA are said to be complementary, meaning that if one side has the sequence GAATAC, the other side will have CTTATG.
- DNA consists of two chains of nucleotides coiled around one another in a right-handed double helix.
- The sugar-phosphate backbones of the two strands spiral around the outside of the helix.
- Nitrogenous bases extend into the center at right angles to the axis of the helix.
- The diameter of the double helix is 2.0 nm.
- Prokaryotic chromosomes are circular DNA molecules that are supercoiled.
- At approximately 40 sites, a complex of proteins is attached to the prokaryotic chromosome forming a series of loops.
- The structure of a prokaryotic chromosome is called the nucleoid.
- Eukaryotic chromosomes have a variety of sizes and numbers.
- A nucleosome consists of a strand of DNA wrapped around a disk of histone proteins to give the appearance of beads on a string.
- The string of beads from eukaryotic chromosomes then coils into a larger structure called the 30 nm fiber.
- Additional proteins from eukaryotic chromosomes coil into a 200 nm fiber.
- Ribonucleic acid (RNA) consists of one strand of nucleotides.
- RNA contains ribose (5C sugar) instead of deoxyribose.
- RNA contains uracil (U) instead of thymine.
- The sugar-phosphate backbone for ribonucleotides is also linked by 3’-5’ phosphodiester bonds.
- Base pairing between U and A and G and C can still occur in RNA.
- Replication is the process by which DNA makes a copy of itself.
- The process of replication is how every new cell receives a copy of DNA.
- DNA replication is semi-conservative, meaning one half of the old strand is always kept in the new strand.
- DNA helicases break the hydrogen bonds linking the bases.
- DNA polymerases move along each strand adding nucleotides according to base pairing rules.
- DNA replication produces two exact copies of the original DNA.
- Each new double helix is composed of one original DNA strand and one new strand.
- Transcription is the process by which a single strand of DNA serves as a template for the synthesis of an RNA molecule.
- Translation converts the information from one language of nitrogenous bases to another of amino acids.
- DNA is in the nucleus.
- Messenger RNA (mRNA) is used to transport DNA instructions to ribosomes.
- The average human has 300 trillion cells.
- The average human has enough DNA to go from the earth to the sun more than 400 times.
- DNA has a diameter of only 0.000000002 meters.
DNA Replication
- The structure of the DNA molecule suggests the mechanism for accurate replication.
- DNA replication is a semi-conservative replication strategy in which one strand is the original or parent strand, and the other is newly synthesized, a daughter strand.
DNA and RNA Vocabulary
- Genetics: The study of genes and heredity
- Trait: Inherited characteristic determined by the presence and expression of alleles.
- Gene: A segment of DNA that codes for a protein, which in turn codes for a trait.
DNA Facts
- Chromosomes: Composed of DNA
- Deoxyribonucleic Acid (DNA): A molecule that stores genetic information within cells
- DNA Replication: Copies itself exactly for new cells
The Role of Proteins
- Proteins: Responsible for all cell structures and functions
- Amino Acids: Proteins are made of long chains of amino acids
- Twenty Amino Acids: There are 20 amino acids in the body
- Protein Function: Proteins are responsible for hair, skin, hormones, muscle movement, antibodies, chemical reactions, and oxygenation of cells.
Why is the Study of DNA Important?
- It’s essential to all life on earth
- Medical Benefits: Disease detection, treatment, and prevention
- Crop Development: Modifying crops for better yield and resistance
- Forensics: Identifying individuals through DNA analysis
DNA Structure
- DNA: A polymer composed of repeating subunits called nucleotides
- DNA Structure: Two long strands, each a chain of nucleotides
- Nucleotide Structure: Composed of a phosphate, a carbon sugar (deoxyribose), and a nitrogen base
Nitrogenous Bases
- Adenine (A) and Guanine (G) are Purines.
- Thymine (T) and Cytosine (C) are Pyrimidines.
DNA Strand and Base Pair Rule
- DNA Strand: Each nucleotide bonds to the next one to form a strand.
- Double Helix: The two strands twist around a central axis.
- Base Pair Rule: Adenine (A) only bonds with Thymine (T) and Cytosine (C) only bonds with Guanine (G).
RNA Structure
- Ribonucleic Acid (RNA): Consists of only one strand of nucleotides
- Ribose: RNA has ribose as its sugar, not deoxyribose.
- Uracil: RNA has uracil (U) as a nitrogenous base instead of thymine.
Prokaryotic Chromosomes
- Prokaryotic Chromosomes: Have a single circular DNA molecule that is supercoiled.
- Nucleoid: A complex of proteins attached to the chromosome forming a series of loops.
Eukaryotic Chromosomes
- Eukaryotic Chromosomes: Vary in number and size.
- Nucleus: True nucleus enclosed by a nuclear membrane.
- Nucleosome: A strand of DNA wrapped around a disk of histone proteins.
- 30 nm Fiber: The string of beads coil into a larger structure.
- 200 nm Fiber: Coiled again with additional proteins.
Replication
- Replication: The process by which DNA makes a copy of itself.
- Cell Division: Replication is necessary for cell division, growth, and reproduction.
- Enzymes: Enzymes unwind and separate the double helix, adding complementary nucleotides to the exposed strands.
- Semi-conservative Replication: The process by which one half of the old strand is always kept in the new strand.
Central Dogma
- Central Dogma: The flow of genetic information is one-way from DNA to RNA to protein.
- Transcription: The process in which a single strand of DNA serves as a template for the synthesis of an RNA molecule.
- Translation: Converts information from nitrogenous bases to amino acids.
Messenger RNA (mRNA)
- mRNA: Transports instructions from the nucleus (where DNA is) to the ribosomes (where proteins are made).
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Description
Test your knowledge on the structure and function of DNA and RNA. This quiz covers the fundamental concepts of genetics, including the roles of genes, chromosomes, and the importance of DNA in heredity and medical applications. Challenge yourself to recall key terms and their definitions related to nucleotides and protein synthesis.