DMT Overview and Dosages
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Questions and Answers

What was the initial step taken to prepare the root-bark for experimentation?

  • Soaking in water
  • Blending into a fine powder (correct)
  • Cutting into small pieces
  • Heating the raw bark
  • What personal protective equipment was used when handling muratic acid?

  • Face mask
  • Thick gloves and eye protection (correct)
  • Apron
  • Rubber boots
  • How was the pH of the water after adding muratic acid measured?

  • Using pH papers (correct)
  • Observing color change
  • Through taste testing
  • Using a digital pH meter
  • What was observed to happen after the jar with the root-bark was shaken?

    <p>It began to foam with pink foam</p> Signup and view all the answers

    How did the dark red color of the solution change by Day 3?

    <p>It turned almost black</p> Signup and view all the answers

    What method was used to heat the solution on Day 4?

    <p>Surrounding it in warm water in a cooking pot</p> Signup and view all the answers

    What layer was formed on top of the mixture in the jar after the initial shaking?

    <p>A pink foam layer</p> Signup and view all the answers

    What was the purpose of making the lid finger tight on the pickle jar during heating?

    <p>To stop evaporation while allowing pressure to escape</p> Signup and view all the answers

    What is the recommended interval before attempting another DMT trip?

    <p>1 hour</p> Signup and view all the answers

    Which of the following substances is suggested to be used for providing NN-DMT in the experiment?

    <p>Mimosa hostilis root-bark</p> Signup and view all the answers

    Taking NN-DMT with MAOIs is generally viewed as:

    <p>never recommended due to health risks</p> Signup and view all the answers

    What is the effect of 5-MeO-DMT in contrast to NN-DMT?

    <p>It is psychedelic without visual distortions.</p> Signup and view all the answers

    What is a primary concern with Bufotenine consumption?

    <p>It can cause fatal circulatory distress.</p> Signup and view all the answers

    What type of acid is referred to as 'pool acid' in the materials list?

    <p>Muratic acid</p> Signup and view all the answers

    What neurotransmitters are affected by inhibiting MAO with MAOIs?

    <p>Serotonin, norepinephrine, and dopamine</p> Signup and view all the answers

    How quickly must the DMT dose be taken to enhance the experience?

    <p>Within 60 seconds</p> Signup and view all the answers

    What is the chemical formula for N,N-Dimethyltryptamine?

    <p>C12H16N2</p> Signup and view all the answers

    Which of the following represents the melting point of DMT?

    <p>44.6-44.8°</p> Signup and view all the answers

    What dosage is typically administered when smoking DMT?

    <p>60-100mg</p> Signup and view all the answers

    What is the significance of the psychological crisis according to the shamen's perspective?

    <p>It is integral for metaphysical realization.</p> Signup and view all the answers

    What is one of the controlled properties of N,N-Dimethyltryptamine as mentioned?

    <p>It is a hallucinogen.</p> Signup and view all the answers

    Which alternative name is used for N,N-Dimethyltryptamine?

    <p>DMT</p> Signup and view all the answers

    What is the boiling point range specified for DMT?

    <p>60-80°</p> Signup and view all the answers

    What does the quote by Timothy Leary suggest about experiences?

    <p>Experiences may vary in duration and impact.</p> Signup and view all the answers

    Which component is primarily associated with the psychedelic properties in Ayahuasca?

    <p>DMT crystals</p> Signup and view all the answers

    What is the primary focus of the book 'Psychedelic Shamanism'?

    <p>The cultivation of psychotropic plants</p> Signup and view all the answers

    Who contributed to the literature 'Tryptamines I Have Known And Loved'?

    <p>Alexander and Ann Shulgin</p> Signup and view all the answers

    What is the ISBN for 'Ayahuasca Analogues: Pangaen Entheogens'?

    <p>0-9614234-5-5</p> Signup and view all the answers

    Which of these sources contains highly technical information about chemical indicators?

    <p>Rhodium</p> Signup and view all the answers

    What should you do after pouring the contents of Jar A into a glass baking dish?

    <p>Allow the solvent to evaporate at room temperature.</p> Signup and view all the answers

    What is a good starting amount of DMT to scrape from the baking pan?

    <p>25mg</p> Signup and view all the answers

    How can you identify the presence of DMT in the final product?

    <p>By its distinct synthetic smell.</p> Signup and view all the answers

    What is the recommended method for heating the DMT during consumption?

    <p>Heat the bulb without touching the DMT.</p> Signup and view all the answers

    What is the aim of washing DMT crystals in water after extraction?

    <p>To remove trace amounts of hydroxide.</p> Signup and view all the answers

    What should you be cautious about when allowing the solvent to evaporate?

    <p>Placing it near an open flame.</p> Signup and view all the answers

    How many doses can potentially be obtained from 30g of mimosa hostilis root-bark?

    <p>5-6 doses</p> Signup and view all the answers

    Which material is NOT listed as necessary for the extraction process?

    <p>Glass beaker</p> Signup and view all the answers

    What was added to jar C after filtering the water from jar B?

    <p>5ml of muratic acid</p> Signup and view all the answers

    The naphtha layer was siphoned out to save the top layer in the jar.

    <p>False</p> Signup and view all the answers

    What should be worn while handling muratic acid?

    <p>thick gloves and proper eye and body protection</p> Signup and view all the answers

    After the solution was shaken with naphtha, the top layer resembled ______ with a few drops of milk added.

    <p>water</p> Signup and view all the answers

    Match the jars with their respective contents or actions:

    <p>Jar A = Cotton T-shirt filter was placed Jar B = Root-bark and solution formed two layers Jar C = Filled with acidic water Turkey Baster = Siphoned out the bottom layer</p> Signup and view all the answers

    What is DMT classified as?

    <p>Hallucinogen</p> Signup and view all the answers

    DMT can be detected in standard drug tests.

    <p>False</p> Signup and view all the answers

    What type of experiences does DMT provide that are different from typical social drugs?

    <p>Psychedelic visions</p> Signup and view all the answers

    DMT is extracted from _____ materials.

    <p>plant</p> Signup and view all the answers

    Match the following terms related to DMT:

    <p>DMT = Powerful hallucinogen LSD = Synthetic hallucinogen Psilocybin = Mushroom-derived compound Schizophrenia = Condition associated with abnormal DMT levels</p> Signup and view all the answers

    Which of the following describes a characteristic of DMT?

    <p>It is naturally formed in the body.</p> Signup and view all the answers

    DMT is considered a recreational drug suitable for inexperienced users.

    <p>False</p> Signup and view all the answers

    What is one of the main reasons for educating about DMT before use?

    <p>To ensure safety and preparedness</p> Signup and view all the answers

    What is the maximum recommended temperature when heating the solution?

    <p>50° C</p> Signup and view all the answers

    The jar should be boiled to facilitate the extraction process.

    <p>False</p> Signup and view all the answers

    What is the purpose of shaking the contents of the jar?

    <p>To help more root-bark come in contact with the acid.</p> Signup and view all the answers

    To filter the contents, plug the bottom of the funnel with ___ or cotton cloth.

    <p>cotton balls</p> Signup and view all the answers

    What should be performed during the second and third extractions?

    <p>Allow more time for the contents to react</p> Signup and view all the answers

    Match the following steps with their corresponding actions:

    <p>Step 2 = Heat the jar with acid Step 3 = Filter the solution Step 4 = Collect extractions Step 5 = Squeeze the cotton-filter</p> Signup and view all the answers

    The initial extraction is the least important in the series of extractions.

    <p>False</p> Signup and view all the answers

    How long should the contents of the jar be heated when using muratic acid?

    <p>15-30 minutes</p> Signup and view all the answers

    Using a ___ filter can be a simple way to separate bulk material from the solution.

    <p>tea strainer</p> Signup and view all the answers

    How long should the contents of the jar be allowed to react during the first extraction?

    <p>24 hours</p> Signup and view all the answers

    What is a consequence of combining MAOIs with NN-DMT?

    <p>It can lead to severe health problems.</p> Signup and view all the answers

    5-MeO-DMT can be taken at the same dosage as NN-DMT.

    <p>False</p> Signup and view all the answers

    What is the recommended time frame for taking the DMT dose?

    <p>within 60 seconds</p> Signup and view all the answers

    The primary material used in the experiment to obtain NN-DMT is __________.

    <p>Mimosa hostilis root-bark</p> Signup and view all the answers

    Which of the following statements about Bufotenine is correct?

    <p>It can cause severe physical discomfort.</p> Signup and view all the answers

    What is the effect of Monoamine Oxidase Inhibitors (MAOIs) on neurotransmitter levels?

    <p>It increases levels of serotonin, norepinephrine, and dopamine.</p> Signup and view all the answers

    What is the first step after combining the solvent fractions in Jar A?

    <p>Pour contents into a glass baking dish.</p> Signup and view all the answers

    The tolerance to DMT builds quickly.

    <p>True</p> Signup and view all the answers

    The evaporation process of the solvent can be expedited by placing the baking dish near an open flame.

    <p>False</p> Signup and view all the answers

    Match the following substances with their respective effects or usages:

    <p>N,N-DMT = Psychedelic effects with visual distortions 5-MeO-DMT = Psychedelic effects without visual distortions Bufotenine = Severe physical discomfort MAOIs = Intensify effects of DMT</p> Signup and view all the answers

    What is the distinct smell associated with DMT?

    <p>A synthetic smell like manufactured plastics.</p> Signup and view all the answers

    After taking NN-DMT, it is advised to wait at least __________ before attempting another trip.

    <p>one hour</p> Signup and view all the answers

    Which of the following best describes the role of tyrosine when MAOIs are used?

    <p>It increases tyramine levels in the blood.</p> Signup and view all the answers

    After pouring contents into the dish, allow for the solvent to ________ over a week.

    <p>evaporate</p> Signup and view all the answers

    How much DMT can potentially be obtained from 30g of mimosa hostilis root-bark?

    <p>5-6 doses</p> Signup and view all the answers

    Washing DMT crystals in water can help reduce the presence of hydroxide.

    <p>True</p> Signup and view all the answers

    After DCM has evaporated, the DMT product may contain trace amounts of ________.

    <p>hydroxide</p> Signup and view all the answers

    Match the DMT extraction steps with their descriptions:

    <ol> <li>Evaporate solvent = A. Removes solvent to leave DMT behind</li> <li>Identify DMT = B. Characterized by synthetic smell</li> <li>Scrape substance = C. Collect final product from dish</li> </ol> Signup and view all the answers

    What should be done with the flame while smoking DMT?

    <p>The flame should never touch the DMT.</p> Signup and view all the answers

    What amount is considered a good starting amount of DMT to scrape from the baking pan?

    <p>About the size of a pea, approximately 25mg</p> Signup and view all the answers

    What is the recommended pH for the water in Jar A?

    <p>2</p> Signup and view all the answers

    When adding acid to water, it is safe to pour water into acid.

    <p>False</p> Signup and view all the answers

    What should be done to ensure the proper acid solution is created in Jar A?

    <p>Test the pH of the water.</p> Signup and view all the answers

    After adding the powdered root-bark, the acid reacts with it to convert alkaloids into ______.

    <p>salts</p> Signup and view all the answers

    What is the approximate volume of acidified water that should be transferred into Jar B?

    <p>8 ounces</p> Signup and view all the answers

    Match the following acids with their source or type:

    <p>Distilled white vinegar = 5% acidity Muratic acid = 30% HCl solution Hydrochloric acid = Reagent grade and potent Sulfuric acid = Very powerful and potent</p> Signup and view all the answers

    Red cabbage juice can be used as an indicator solution for measuring pH.

    <p>True</p> Signup and view all the answers

    A glass stirring rod or non-corrosive tool should be used to ______ the acidic solution.

    <p>stir</p> Signup and view all the answers

    What pH was observed after adding 10 teaspoons of the base solution?

    <p>11-12</p> Signup and view all the answers

    The solution separated into two layers by Day 12.

    <p>False</p> Signup and view all the answers

    What color did the mixture change to after the addition of the base solution initially?

    <p>very grayish blue</p> Signup and view all the answers

    The pH of the aqueous solution tested on Day 14 was close to ______.

    <p>9 or 10</p> Signup and view all the answers

    Match the days with their corresponding observations:

    <p>Day 10 = Color changed from burgundy red to grayish blue Day 11 = Solution still resembles thick oily foam Day 12 = Markings made on the side of the jar Day 14 = Measured pH of the aqueous solution</p> Signup and view all the answers

    What is the maximum temperature recommended to maintain while heating the solution?

    <p>50° C</p> Signup and view all the answers

    It is safe to boil the solution when preparing the extraction.

    <p>False</p> Signup and view all the answers

    How long should the contents of the jar be allowed to react during the first extraction?

    <p>24 hours</p> Signup and view all the answers

    To create a cotton-filter, plug the bottom of the funnel with __________.

    <p>cotton balls</p> Signup and view all the answers

    Match the following steps with their corresponding actions:

    <p>Step 1 = Allow contents to react for 24 hours Step 2 = Shaking the jar periodically Step 3 = Filtration Step 4 = Collecting extractions</p> Signup and view all the answers

    What should be done to improve filtration efficiency?

    <p>Filter thinner parts of the solution first</p> Signup and view all the answers

    A vacuum filter is a recommended method for efficient filtration.

    <p>True</p> Signup and view all the answers

    What should be used to maintain temperature while heating the solution?

    <p>Double boiler</p> Signup and view all the answers

    The alkaloids from the root-bark are converted into __________ during the extraction process.

    <p>salts</p> Signup and view all the answers

    What should not be done while heating the pickle jar?

    <p>Both A and B</p> Signup and view all the answers

    What was added to jar C after it was filled with filtered water?

    <p>5 ml of muratic acid</p> Signup and view all the answers

    The contents of jar A were filtered through a cotton T-shirt filter.

    <p>True</p> Signup and view all the answers

    What safety equipment is essential when working with chemicals like muratic acid?

    <p>thick gloves and proper eye protection</p> Signup and view all the answers

    After the jar was shaken with naphtha, the top layer resembled ______ with a few drops of milk added.

    <p>water</p> Signup and view all the answers

    Match the jars to their respective actions:

    <p>Jar A = Filled with root-bark and saturated with water Jar B = Contains sediment after filtering Jar C = Contains acidified water Naphtha = Used to separate substances in the mixture</p> Signup and view all the answers

    What was done with the plant material after Day 9?

    <p>It was disposed of</p> Signup and view all the answers

    It is safe to handle naphtha without any gloves.

    <p>False</p> Signup and view all the answers

    What was the purpose of twisting and squeezing the cotton filter?

    <p>To extract remaining liquid from the sediment</p> Signup and view all the answers

    The process was repeated until jar B was ______.

    <p>empty</p> Signup and view all the answers

    What did the operator use to siphon the contents of the jar?

    <p>A turkey bastor</p> Signup and view all the answers

    What color does the solution change to as alkaloids transition from acid salts to free base?

    <p>Gray</p> Signup and view all the answers

    The emulsion formed by rapid stirring separates quickly.

    <p>False</p> Signup and view all the answers

    What should be added to help the polar layer become more effective in breaking emulsions?

    <p>salt</p> Signup and view all the answers

    The solution in Jar B will turn _____ and slippery as more base is added.

    <p>black</p> Signup and view all the answers

    Match the solvent with its characteristic:

    <p>Naphtha = Creates a thick orange emulsion that takes over 48 hours to separate. DCM = Sinks and allows for faster emulsion resolving. Methanol = Requires at least 4 days for reactions to complete. Aqueous solution = Where elf-spice falls after becoming basified.</p> Signup and view all the answers

    What happens to the jar as the pH of the contents approaches 11-12?

    <p>It becomes pressurized.</p> Signup and view all the answers

    Keeping the naphtha warm increases the amount of alkaloids extracted.

    <p>True</p> Signup and view all the answers

    How long should you normally wait for the emulsion to separate into two distinct layers?

    <p>overnight</p> Signup and view all the answers

    If using _____ as the extraction solvent, expect a faster resolving emulsion than naphtha.

    <p>DCM</p> Signup and view all the answers

    What does the solution typically resemble after adding more base?

    <p>Thick gel</p> Signup and view all the answers

    What is the melting point range of N,N-Dimethyltryptamine?

    <p>44.6-44.8°</p> Signup and view all the answers

    DMT is classified as a hallucinogen according to U.S. regulations.

    <p>True</p> Signup and view all the answers

    What is the chemical formula for N,N-Dimethyltryptamine?

    <p>C12H16N2</p> Signup and view all the answers

    DMT is considered to be extracted from __________ materials.

    <p>plant</p> Signup and view all the answers

    Match the following dosages with their respective methods of administration:

    <p>Intravenously = 4-30mg Smoking = 60-100mg Intramuscularly = 60-100mg Orally = &gt;350mg</p> Signup and view all the answers

    What color did the mixture change to after 4 teaspoons of base solution were added?

    <p>Grayish blue</p> Signup and view all the answers

    The pH increased to approximately 12 after 10 teaspoons of base solution were added.

    <p>True</p> Signup and view all the answers

    According to shamen knowledge, what is a crucial aspect of personal metaphysical realization?

    <p>Engaging in intense experiences.</p> Signup and view all the answers

    What was observed in jar B after adding 2 teaspoons of base solution?

    <p>A clear layer appeared on top of the jar followed by thick orange bubbles.</p> Signup and view all the answers

    The boiling point of DMT is the same as its melting point.

    <p>False</p> Signup and view all the answers

    Who is quoted in the text with the statement about experiences lasting for a million years and for a split-second?

    <p>Timothy Leary</p> Signup and view all the answers

    After adding salt to the mixture, the outcome was _____ in the solution.

    <p>no change</p> Signup and view all the answers

    Match the following observations with their corresponding days:

    <p>Day 10 = Mixture turns inky black and foam appears Day 12 = No change in layers after 48 hours Day 13 = Salt is added and stirred for 30 minutes Day 14 = pH is tested and is hard to measure due to dark color</p> Signup and view all the answers

    What is the purpose of basifying the solution in this experiment?

    <p>To transform alkaloids into their free base form</p> Signup and view all the answers

    Lye is used in the basifying step of the extraction process.

    <p>True</p> Signup and view all the answers

    What safety measure should be taken before handling lye?

    <p>Wear gloves and goggles</p> Signup and view all the answers

    The lower fraction of the fluids in a separatory funnel can be drained via the ______.

    <p>bottom faucet</p> Signup and view all the answers

    Match the following steps or components with their correct descriptions:

    <p>Warm naphtha = Organic non-polar solvent used for extraction Ammonium hydroxide = Commonly used as a basifying agent Lye = A caustic substance found in household drain cleaners Separatory funnel = Used for separating layers of liquid</p> Signup and view all the answers

    What pH should the solution reach after the basifying process?

    <p>Approximately 12</p> Signup and view all the answers

    A Ziplock bag can function as a makeshift separatory funnel.

    <p>True</p> Signup and view all the answers

    How much warm naphtha is added to Jar B?

    <p>100ml (approximately 3 ounces)</p> Signup and view all the answers

    After adding lye to water, the solution is shaken to ensure it is ______.

    <p>mixed thoroughly</p> Signup and view all the answers

    The solubility of alkaloids in water increases after they are basified.

    <p>False</p> Signup and view all the answers

    What was added to jar C after filtering the water from jar B?

    <p>5ml of muratic acid</p> Signup and view all the answers

    What is the purpose of adding acid to water in Jar A?

    <p>To acidify the water for alkaloid conversion</p> Signup and view all the answers

    The siphoning process was conducted to remove the bottom layer from the jar.

    <p>False</p> Signup and view all the answers

    It is advisable to add water to acid to achieve the desired pH.

    <p>False</p> Signup and view all the answers

    What should the pH of the water in Jar A be after acidification?

    <p>2</p> Signup and view all the answers

    What was done to the filtered sediment in jar B before siphoning?

    <p>The edges of the filter were twisted to squeeze any remaining liquid.</p> Signup and view all the answers

    Jar B is filled with ___________ root-bark for alkaloid conversion.

    <p>powdered</p> Signup and view all the answers

    The jar containing the acidic solution was allowed to sit in warm water for _____ minutes.

    <p>30</p> Signup and view all the answers

    What is recommended to use for measuring pH if pH strips are not available?

    <p>Red cabbage or red beet juice</p> Signup and view all the answers

    What method was used to prevent naphtha from entering the baster while siphoning?

    <p>Squeezing the baster bulb slowly</p> Signup and view all the answers

    The final collection of the aqueous solution was completed on Day 9.

    <p>True</p> Signup and view all the answers

    Match the types of acid with their source:

    <p>Distilled white vinegar = 5% acidity, commonly available Muratic acid = Pool shops Hydrochloric acid = Reagent grade, potent Sulfuric acid = Reagent grade, potent</p> Signup and view all the answers

    How long was the jar shaken with naphtha during the extraction process?

    <p>About 10 minutes</p> Signup and view all the answers

    Muriatic acid is recommended to be used undiluted in the extraction process.

    <p>False</p> Signup and view all the answers

    What substance is formed when acid reacts with the root-bark in Jar B?

    <p>Salts</p> Signup and view all the answers

    Match the following jars with their content or action:

    <p>Jar A = Filtered water Jar B = Sediment and solution Jar C = Acidified solution Jar D = Naphtha</p> Signup and view all the answers

    What is the estimated volume of acidified water to be transferred to Jar B?

    <p>8 ounces</p> Signup and view all the answers

    A _____ T-shirt filter was used inside the funnel in jar A.

    <p>cotton</p> Signup and view all the answers

    To prevent dangerous reactions, always add acid into __________.

    <p>water</p> Signup and view all the answers

    What was the purpose of allowing the solution to rest for 24 hours after shaking?

    <p>To allow layers to separate</p> Signup and view all the answers

    What is the purpose of using a paper coffee-filter instead of a cotton filter in the final filtration of Jar C?

    <p>To achieve finer filtration and remove more particulates</p> Signup and view all the answers

    Naphtha and ether are examples of non-polar solvents used in the defatting step.

    <p>True</p> Signup and view all the answers

    What should be done after collecting the acidic contents in Jar C?

    <p>Filter the contents using a paper coffee-filter.</p> Signup and view all the answers

    All DMT salts are insoluble in ______ solvents.

    <p>non-polar</p> Signup and view all the answers

    Match the following extraction phases with their descriptions:

    <p>First extraction phase = Converts majority of alkaloids to salts Second extraction phase = Takes a longer period for extended alkaloid recovery Third extraction phase = Can be reduced to 1-2 days but yields may be lower Defatting = Removes oils and fats from the solution</p> Signup and view all the answers

    Which step is important before adding any organic solvent to the acidic solution?

    <p>Evaporate a significant amount of the solvent to check for residues</p> Signup and view all the answers

    The defatting process is always necessary when extracting from all types of plant materials.

    <p>False</p> Signup and view all the answers

    What should you do with the remaining root-bark after the extraction phases?

    <p>Dispose of it.</p> Signup and view all the answers

    What was the purpose of adding a 5% base solution to the main solution in the experiment?

    <p>To raise the pH</p> Signup and view all the answers

    The naphtha was added to the solution to increase its viscosity.

    <p>False</p> Signup and view all the answers

    What substance was used to cover the grass in jar B?

    <p>acidified water</p> Signup and view all the answers

    After 24 hours of rest, the _____ was skimmed off the top along with the naphtha solvent.

    <p>nasty stuff</p> Signup and view all the answers

    Match the days with their corresponding actions during the experiment:

    <p>Day 12 = Filter contents from jar B into jar A Day 19 = Collect aqueous solution from jar A Day 26 = Final collection of aqueous solution Day 39 = Pour solvent fractions into a baking dish</p> Signup and view all the answers

    What is the primary purpose of using naphtha in the extraction process?

    <p>To act as a defatting agent</p> Signup and view all the answers

    Methylene chloride is also known as dichloromethane and is considered safe to use without precautions.

    <p>False</p> Signup and view all the answers

    What should you do if you are unsure about the contaminants present in a solvent?

    <p>Evaporate a small amount in a dish and inspect the residue.</p> Signup and view all the answers

    ______ is considered more selective for catching alkaloids than DCM.

    <p>Naphtha</p> Signup and view all the answers

    Match the solvent with its characteristic feature:

    <p>Naphtha = Rises to the top of the jar Methylene Chloride = Sinks to the bottom of the jar Ether = Floats to the top of the jar Chloroform = Sinks to the bottom of the jar</p> Signup and view all the answers

    What is an important physical property of Chloroform?

    <p>It has a boiling range of 35-65°C</p> Signup and view all the answers

    Cool naphtha is more effective for extracting alkaloids than warm naphtha.

    <p>False</p> Signup and view all the answers

    What is the first step after adding naphtha to jar B?

    <p>Cap the lid on Jar B and shake the contents vigorously for 20 minutes.</p> Signup and view all the answers

    Methylene chloride must be distilled from non-flammable _____ before use.

    <p>paint strippers</p> Signup and view all the answers

    What is an appropriate way to remove liquid ether from an engine-starting aerosol can?

    <p>Spray it down a PVC pipe</p> Signup and view all the answers

    What method is suggested for mixing the two solutions in the jar?

    <p>Tipping the jar end over end</p> Signup and view all the answers

    The larger crystals observed on Day 21 were completely dry.

    <p>False</p> Signup and view all the answers

    What substance was added to the pickle jar along with water on Day 3?

    <p>5ml muriatic acid</p> Signup and view all the answers

    During the evaporation process from Day 17 to Day 20, small ______ formations were observed at the bottom of the dish.

    <p>yellow/orange crystal</p> Signup and view all the answers

    Match the days with their corresponding observations:

    <p>Day 15 = Top layer was saved Day 16 = Combined fractions poured for evaporation Day 22 = Crystals smeared onto card Day 24 = Experiment was a success</p> Signup and view all the answers

    Which material was used to help in pulverizing the Phalaris grass?

    <p>A small amount of water</p> Signup and view all the answers

    The crystals scraped off after drying revealed a more gum-like consistency than crystalline.

    <p>False</p> Signup and view all the answers

    How long did it take to pulverize the Phalaris grass sufficiently?

    <p>Over an hour</p> Signup and view all the answers

    The mixture of grass clippings and water was placed into a baggie, frozen, and ______ several times.

    <p>thawed</p> Signup and view all the answers

    What was the primary observation after scraping the dish on Day 23?

    <p>Crystals bunched together</p> Signup and view all the answers

    What is the purpose of using warm naphtha in the process described?

    <p>To facilitate the extraction of alkaloids</p> Signup and view all the answers

    Ammonium hydroxide is the only base that can be used for basifying the solution in this process.

    <p>False</p> Signup and view all the answers

    What is the desired pH level to achieve during the basifying process?

    <p>11</p> Signup and view all the answers

    A separatory funnel is used to separate different ________ in a mixture.

    <p>layers</p> Signup and view all the answers

    Match the chemical with its use in the process:

    <p>Naphtha = Extraction of alkaloids NaOH = Basifying agent Lye = Caustic base for preparation Water = Solvent for lye dilution</p> Signup and view all the answers

    What is one common method to drain the lower fraction of fluids in a separatory funnel?

    <p>Opening the bottom faucet</p> Signup and view all the answers

    The use of lye in the basifying process is safe and requires no precautions.

    <p>False</p> Signup and view all the answers

    What should be tested to ensure safe use of a Ziplock baggie as a quick separatory funnel?

    <p>That the solvents will not melt it</p> Signup and view all the answers

    After mixing, the layers should be allowed to _____ before separating.

    <p>settle</p> Signup and view all the answers

    What is the primary outcome of basifying the substance?

    <p>Transformation into free base form</p> Signup and view all the answers

    What pH was recorded after adding 8 teaspoons of base solution?

    <p>10</p> Signup and view all the answers

    The mixture separated into two layers after several days.

    <p>False</p> Signup and view all the answers

    What was added to the solution on Day 13?

    <p>Salt</p> Signup and view all the answers

    After adding a total of 10 teaspoons of base solution, the mixture turned ______.

    <p>inky black</p> Signup and view all the answers

    Match the actions taken with their corresponding days:

    <p>Day 10 = Testing pH after adding base solution Day 12 = Adding more solvent Day 14 = Testing aqueous solution pH Day 13 = Adding salt to the mixture</p> Signup and view all the answers

    What is the molecular weight of N,N-Dimethyltryptamine?

    <p>188.27</p> Signup and view all the answers

    The boiling point of DMT ranges from 70-100°.

    <p>False</p> Signup and view all the answers

    What is the chemical formula for N,N-Dimethyltryptamine?

    <p>C12H16N2</p> Signup and view all the answers

    N,N-Dimethyltryptamine is also known as ______.

    <p>DMT</p> Signup and view all the answers

    Which dosage is typically administered when smoking DMT?

    <p>60-100mg</p> Signup and view all the answers

    Match the following dosages with their methods of administration:

    <p>4-30mg = Intravenously 60-100mg = Subcutaneously</p> <blockquote> <p>350mg = Orally</p> </blockquote> Signup and view all the answers

    DMT is classified as a non-controlled substance in the U.S.

    <p>False</p> Signup and view all the answers

    According to shamen, what is essential for an individual’s inward path?

    <p>Rituals</p> Signup and view all the answers

    Which plant has the highest reported content of 5-MeO-DMT?

    <p>Pilocarpus organensis</p> Signup and view all the answers

    DMT is known to be active when taken orally.

    <p>False</p> Signup and view all the answers

    What is the common name for N,N-Dimethyltryptamine?

    <p>DMT</p> Signup and view all the answers

    Acacia simplicifolia bark contains __% NN-DMT.

    <p>0.86</p> Signup and view all the answers

    Match the following plants with their NN-DMT content:

    <p>Acacia maidenii bark = 0.36% Mimosa hostilis root = 0.57% Phalaris tuberosa = 0.10% Desmanthus illinoensis = 0.34%</p> Signup and view all the answers

    Which of the following plants does not contain NN-DMT?

    <p>Pilocarpus organensis</p> Signup and view all the answers

    5-OH-DMT is considered a close cousin of NN-DMT.

    <p>True</p> Signup and view all the answers

    What must DMT be smoked in order to experience its effects?

    <p>freebase form</p> Signup and view all the answers

    The alkaloid content in plant materials can vary due to ___.

    <p>growing conditions</p> Signup and view all the answers

    What is the percentage of NN-DMT in Phalaris arundinacea?

    <p>0.060%</p> Signup and view all the answers

    What can increase the effects of NN-DMT?

    <p>MAOIs</p> Signup and view all the answers

    5-MeO-DMT is taken at half the dose of NN-DMT.

    <p>False</p> Signup and view all the answers

    What severe physical discomforts can Bufotenine cause?

    <p>Circulatory distress, nausea, psychological distress, severe skin flushing, potential death.</p> Signup and view all the answers

    The primary material used for NN-DMT extraction is __________ hostilis root-bark.

    <p>Mimosa</p> Signup and view all the answers

    Match the following substances with their effects or properties:

    <p>5-MeO-DMT = Psychedelic without visual distortions Bufotenine = Severe discomfort and potential fatality MAOIs = Increase neurotransmitter levels Naphtha = Solvent for extraction</p> Signup and view all the answers

    What is the recommended time frame to wait before attempting another DMT trip?

    <p>1 hour</p> Signup and view all the answers

    A person can safely combine MAOIs with other drugs without concern.

    <p>False</p> Signup and view all the answers

    What should be tested for adverse reactions during the extraction process?

    <p>Non-glass materials with solvents.</p> Signup and view all the answers

    The chemical that is metabolized by MAO in the body includes serotonin, norepinephrine, and __________.

    <p>dopamine</p> Signup and view all the answers

    Match the following materials with their purposes in the extraction process:

    <p>Muratic acid = Acidic agent in extraction pH papers = Measurement of acidity Lye = Base for reaction Naphtha = Solvent extraction</p> Signup and view all the answers

    What is the primary purpose of using a separatory funnel?

    <p>To separate the liquid layers</p> Signup and view all the answers

    Ammonium hydroxide is used in this experiment as the basifying agent.

    <p>False</p> Signup and view all the answers

    What is the pH level we need to achieve in order to basify the solution?

    <p>11</p> Signup and view all the answers

    A mixture for basifying consists of __________ of lye mixed with __________ of water.

    <p>5g, 95g</p> Signup and view all the answers

    Match the following substances with their respective roles in the experiment:

    <p>Naphtha = Solvent for extraction Lye = Basifying agent Water = Diluent for lye Separatory funnel = Device for liquid separation</p> Signup and view all the answers

    What occurs to alkaloids after they are basified?

    <p>They are transformed into their free base form</p> Signup and view all the answers

    It is acceptable to mix lye directly into a concentrated solution.

    <p>False</p> Signup and view all the answers

    How long should you shake Jar B after adding warm naphtha?

    <p>5 minutes</p> Signup and view all the answers

    To prevent the baggie from melting when used as a separatory funnel, it is suggested to __________.

    <p>test the baggie</p> Signup and view all the answers

    What is the importance of slowly adding lye to water in this process?

    <p>To prevent hazardous reactions</p> Signup and view all the answers

    What is the status of DMT in the United States?

    <p>It is illegal and controlled under federal regulations.</p> Signup and view all the answers

    DMT is often sold through dealers.

    <p>False</p> Signup and view all the answers

    What does DMT stand for?

    <p>N,N-Dimethyltryptamine</p> Signup and view all the answers

    DMT is related to _____ and psilocybin.

    <p>LSD</p> Signup and view all the answers

    Match the following hallucinogens with their characteristics:

    <p>DMT = Powerful hallucinogen, not a social drug LSD = Widely used as a recreational drug Psilocybin = Derived from mushrooms 5-MeO-DMT = Known for intense experiences</p> Signup and view all the answers

    Which of the following is a recommended practice when considering DMT use?

    <p>Educate yourself about the drug and its effects.</p> Signup and view all the answers

    It is recommended that inexperienced users try DMT for recreational purposes.

    <p>False</p> Signup and view all the answers

    What is one psychological effect associated with high levels of DMT in schizophrenia patients?

    <p>Abnormal levels of DMT</p> Signup and view all the answers

    DMT can be extracted from common _____ materials.

    <p>plant</p> Signup and view all the answers

    What type of experiences can DMT provide that differ from typical social drugs?

    <p>Intense and sometimes frightening visions.</p> Signup and view all the answers

    What does the remaining substance from the evaporation process resemble?

    <p>Sticky orangish goo or white crystals</p> Signup and view all the answers

    The flame should directly touch the DMT during consumption.

    <p>False</p> Signup and view all the answers

    What is the recommended initial amount of DMT to scrape from the baking pan?

    <p>25mg</p> Signup and view all the answers

    You can help reduce unpleasant hydroxide in the final product by washing the DMT crystals in ______.

    <p>water</p> Signup and view all the answers

    Match the materials used in the DMT extraction process with their primary purpose.

    <p>Mimosa hostilis root-bark = Source of NN-DMT Pool acid = pH adjustment Red Devil Lye = Base for extraction Coffee filter = Filtration of mixture</p> Signup and view all the answers

    What is the boiling point range of N,N-Dimethyltryptamine (DMT)?

    <p>60-80°</p> Signup and view all the answers

    N,N-Dimethyltryptamine is classified as a hallucinogenic substance in the U.S.

    <p>True</p> Signup and view all the answers

    What is the molecular weight of N,N-Dimethyltryptamine?

    <p>188.27</p> Signup and view all the answers

    The chemical formula for N,N-Dimethyltryptamine is ______.

    <p>C12H16N2</p> Signup and view all the answers

    Match the following dosages with their administration method:

    <p>Intravenously = 4-30mg Smoking = 60-100mg Orally = &gt;350mg Intramuscularly = 60-100mg</p> Signup and view all the answers

    According to shamanic beliefs, which experience is crucial for metaphysical realization?

    <p>Intense psychological crisis</p> Signup and view all the answers

    DMT does not persist in the body and is detectable in standard drug tests.

    <p>False</p> Signup and view all the answers

    What alternative name is used for N,N-Dimethyltryptamine?

    <p>DMT</p> Signup and view all the answers

    What is the function of a separatory funnel in the extraction process?

    <p>To separate layers of solutions.</p> Signup and view all the answers

    Ammonium hydroxide is normally used for basifying the solution in this extraction process.

    <p>False</p> Signup and view all the answers

    What is a recommended solvent for the extraction process?

    <p>Warm naphtha</p> Signup and view all the answers

    To basify the solution, lye is mixed with __________ to create a solution with a pH of approximately 12.

    <p>water</p> Signup and view all the answers

    What is the approximate amount of lye recommended to mix with water for basifying?

    <p>5g (~0.2 ounces)</p> Signup and view all the answers

    The upper layer of the solution after mixing will contain the alkaloids in salt form.

    <p>False</p> Signup and view all the answers

    What is the purpose of adding a proper amount of water before introducing lye?

    <p>To prevent localized pH spikes</p> Signup and view all the answers

    Match the following jars with their respective contents or actions:

    <p>Jar A = Lye and water mixture Jar B = Solution with warm naphtha Jar C = Filtered solution Jar D = Final product collection</p> Signup and view all the answers

    After shaking the solution, the __________ layer containing naphtha can be siphoned out.

    <p>top</p> Signup and view all the answers

    How long should the jar with naphtha be shaken for optimal results?

    <p>5 minutes</p> Signup and view all the answers

    Which plant contains the highest percentage of 5-MeO-DMT?

    <p>Pilocarpus organensis</p> Signup and view all the answers

    DMT is active when consumed orally without any additional substances.

    <p>False</p> Signup and view all the answers

    What is the alkaloid content of Acacia simplicifolia bark per 100g?

    <p>0.86% NN-DMT</p> Signup and view all the answers

    Phalaris tuberosa contains _____% NN-DMT.

    <p>0.10</p> Signup and view all the answers

    Match each plant with its corresponding alkaloid:

    <p>Mimosa hostilis root bark = 0.57% NN-DMT Desmanthus illinoensis root bark = 0.34% NN-DMT Virola shoots &amp; flowers = 0.44% NN-DMT Phalaris arundinacea = 0.060% NN-DMT</p> Signup and view all the answers

    Which of the following is a close cousin to DMT?

    <p>5-MeO-DMT</p> Signup and view all the answers

    DMT can be found growing wild and free in many parts of the world.

    <p>True</p> Signup and view all the answers

    What must be done to DMT to experience its effects?

    <p>It must be smoked in its freebase form.</p> Signup and view all the answers

    Acacia maidenii bark contains _____% NN-DMT.

    <p>0.36</p> Signup and view all the answers

    What is the reported alkaloid percentage of NN-DMT in Phalaris tuberosa?

    <p>0.10%</p> Signup and view all the answers

    Which of the following plants has the highest percentage of NN-DMT content?

    <p>Acacia simplicifolia bark</p> Signup and view all the answers

    DMT is active orally without any preparation.

    <p>False</p> Signup and view all the answers

    What compound must DMT be in to be smoked and experience its effects?

    <p>freebase form</p> Signup and view all the answers

    Acacia bark contains ______% NN-DMT.

    <p>0.71</p> Signup and view all the answers

    Match the following plants with their alkaloid content:

    <p>Acacia maidenii bark = 0.36% NN-DMT Virola shoots &amp; flowers = 0.44% NN-DMT Desmanthus illinoensis root = 0.34% NN-DMT Phalaris arundinacea = 0.060% NN-DMT</p> Signup and view all the answers

    Which alkaloid is found in Pilocarpus organensis?

    <p>5-MeO-DMT</p> Signup and view all the answers

    All of the plants mentioned can be found growing wild and are legal.

    <p>True</p> Signup and view all the answers

    What is the approximate NN-DMT content in Phalaris tuberosa?

    <p>0.10</p> Signup and view all the answers

    What was added to jar C to create an acidic solution?

    <p>Muratic acid</p> Signup and view all the answers

    The sediments from the filter were discarded after the filtering process.

    <p>False</p> Signup and view all the answers

    How long was the mixture allowed to sit after the naphtha was added?

    <p>24 hours</p> Signup and view all the answers

    After shaking the jar with naphtha, the top layer resembles ______.

    <p>water</p> Signup and view all the answers

    What method was used to remove the naphtha layer from the jar?

    <p>Siphoning</p> Signup and view all the answers

    Match the jars with their respective contents or actions:

    <p>Jar A = Filled with root-bark solution Jar B = Holds sediments after filtering Jar C = Contains acidic water Jar B (after naphtha addition) = Top layer removal</p> Signup and view all the answers

    The contents of jar A were filtered before being poured into jar C.

    <p>False</p> Signup and view all the answers

    What was used to filter the smaller particles in jar A?

    <p>Cotton T-shirt filter</p> Signup and view all the answers

    What safety equipment is recommended while handling muratic acid?

    <p>Gloves and goggles</p> Signup and view all the answers

    The jar containing the remaining nasty naphtha stuff should be ______ after siphoning out the bottom layer.

    <p>cleaned out</p> Signup and view all the answers

    What was the method used to mix the two solutions in the jar to obtain an emulsion?

    <p>Tipping the jar end over end slowly</p> Signup and view all the answers

    The crystals observed after the evaporation process on Days 17-20 were described as being yellow or orange in color.

    <p>True</p> Signup and view all the answers

    What substance was used to help pulverize Phalaris grass?

    <p>Water</p> Signup and view all the answers

    On Day 3, _____ acid was added to the pickle jar that contained roughly 500ml water.

    <p>muratic</p> Signup and view all the answers

    Match the days of the experiment with their corresponding observations:

    <p>Day 21 = Crystals have dried at the edges Day 22 = Entire dish scraped with a razor Day 23 = Brownish goo reveals crystalline structure Day 24 = Experiment declared a success</p> Signup and view all the answers

    What is the ideal size of DMT to scrape from the baking pan?

    <p>25mg</p> Signup and view all the answers

    DMT has a pleasant floral smell when in its final recovered form.

    <p>False</p> Signup and view all the answers

    What should be avoided while allowing the solvent to evaporate?

    <p>Heat or open flame</p> Signup and view all the answers

    To help reduce unpleasant hydroxide in the final product, washing the DMT crystals in _____ is recommended.

    <p>water</p> Signup and view all the answers

    Match the following substances or actions with their associated descriptions:

    <p>Mimosa hostilis root-bark = Source of NN-DMT Red Devil Lye = Used for base extraction Solvent evaporation = Removes volatile liquids Glass baking dish = Container for solvent recovery</p> Signup and view all the answers

    What is the potential yield of DMT doses from 30g of mimosa hostilis root-bark assuming best yields?

    <p>5-6 doses</p> Signup and view all the answers

    DMT should be smoked quickly for immediate effect.

    <p>True</p> Signup and view all the answers

    What is the appearance of DMT after the solvent has evaporated?

    <p>Sticky orangish goo or white/pale-orange crystals</p> Signup and view all the answers

    After pouring the contents of Jar A into a glass baking dish, allow for the solvent to _____ .

    <p>evaporate</p> Signup and view all the answers

    What is an essential caution to remember when consuming DMT?

    <p>Heat the bulb without letting the flame touch the DMT</p> Signup and view all the answers

    What is the purpose of warming naphtha before adding it to the solution?

    <p>To reduce the viscosity and help solubilize the alkaloids</p> Signup and view all the answers

    Ammonium hydroxide is typically used for basifying the solution instead of NaOH.

    <p>False</p> Signup and view all the answers

    What pH should the solution be adjusted to before transferring it into Jar B?

    <p>11</p> Signup and view all the answers

    NaOH is found in household lye crystals, commonly referred to as _____ drain cleaner.

    <p>Red Devil</p> Signup and view all the answers

    Match the following solvents with their properties:

    <p>Naphtha = Non-polar organic solvent Ammonium hydroxide = Commonly used to basify Lye = Found in household products Water = Solvent for dissolving salts</p> Signup and view all the answers

    What is created when the alkaloid is transformed into its free base form?

    <p>It is extracted with non-polar solvents</p> Signup and view all the answers

    The separatory funnel can be used to effectively separate two distinct layers of liquids.

    <p>True</p> Signup and view all the answers

    How long should the jar containing warm naphtha be shaken?

    <p>5 minutes</p> Signup and view all the answers

    Before discarding the solvent layer, it is recommended to repeat the defatting process _____ times.

    <p>2</p> Signup and view all the answers

    What is the main reason for diluting the lye solution before adding it to the mixture?

    <p>To prevent localized pH spikes</p> Signup and view all the answers

    What occurs to the solution color as alkaloids are turned from acid salts to free base?

    <p>It turns gray</p> Signup and view all the answers

    A thick emulsion takes less than 24 hours to settle out after stirring.

    <p>False</p> Signup and view all the answers

    What should be added to help the polar layer become more polar when an emulsion has not cleared?

    <p>Salt</p> Signup and view all the answers

    The naphtha will create a thick orange emulsion with small bubbles that sometimes takes over ______ hours to separate.

    <p>48</p> Signup and view all the answers

    Match the solvent used during extraction with its characteristic behavior:

    <p>Naphtha = Floats and creates a thick emulsion DCM = Sinks and resolves emulsion quickly Methanol = Requires 4 days for reaction completion Salt = Enhances the polar nature of the solution</p> Signup and view all the answers

    How long should you wait to allow the contents of Jar B to react completely when using DCM?

    <p>24 hours</p> Signup and view all the answers

    Keeping naphtha warm decreases the amount of alkaloids it extracts.

    <p>False</p> Signup and view all the answers

    What is one method suggested for increasing the emulsion breaking down process?

    <p>Gentle stirring</p> Signup and view all the answers

    After completing the extraction, the alkaloids fall from the ______ aqueous solution into our solvent.

    <p>basified</p> Signup and view all the answers

    What visual change occurs to the naphtha layer as the extraction process continues?

    <p>It turns darker color, usually reddish-brown or yellow</p> Signup and view all the answers

    Which of the following is a primary focus of the book 'Psychedelic Shamanism'?

    <p>Cultivation, preparation, and shamanic use of psychotropic plants</p> Signup and view all the answers

    DMT is considered a recreational drug suitable for inexperienced users.

    <p>False</p> Signup and view all the answers

    What is one of the main reasons for educating about DMT before use?

    <p>To ensure safety and understanding of its effects.</p> Signup and view all the answers

    DMT is extracted from _____ materials.

    <p>plant</p> Signup and view all the answers

    Match the following authors with their works:

    <p>Jim DeKorne = Psychedelic Shamanism Jonathan Ott = Ayahuasca Analogues Alexander and Ann Shulgin = Tryptamines I Have Known And Loved</p> Signup and view all the answers

    How long did the contents of the jar need to settle after mixing to form an emulsion?

    <p>2-3 hours</p> Signup and view all the answers

    The mixture of Phalaris grass was successfully pulverized without adding any water.

    <p>False</p> Signup and view all the answers

    What did the brownish goo resemble after drying up on Day 23?

    <p>more crystalline structure</p> Signup and view all the answers

    After adding muratic acid, the solution's pH was measured using _______ papers.

    <p>litmus</p> Signup and view all the answers

    Match the days with their respective observations or actions:

    <p>Day 21 = Crystals edges dried a bit Day 22 = Entire dish scraped with a razor Day 23 = Brownish goo dried Day 24 = Experiment marked as a success</p> Signup and view all the answers

    Which substance was added to the mixture on Day 3?

    <p>Pool acid</p> Signup and view all the answers

    The Phalaris grass extraction process included freezing and thawing the mixture multiple times.

    <p>True</p> Signup and view all the answers

    What was the method used to mix the two solutions described in the content?

    <p>slowly tipping the jar end over end</p> Signup and view all the answers

    On Day 20, the evaporation process lasted for ______ days.

    <p>3</p> Signup and view all the answers

    What was the texture of the crystals observed on Day 20?

    <p>Circular and yellow/orange</p> Signup and view all the answers

    What substance is recommended for obtaining a pure form of NN-DMT?

    <p>Mimosa hostilis root-bark</p> Signup and view all the answers

    5-MeO-DMT causes visual distortions similar to NN-DMT.

    <p>False</p> Signup and view all the answers

    What is a primary effect of consuming Bufotenine?

    <p>Severe physical discomfort</p> Signup and view all the answers

    NN-DMT should be taken within _____ seconds for the experience to be enhanced.

    <p>60</p> Signup and view all the answers

    Match the following terms related to DMT with their descriptions:

    <p>N,N-DMT = Main psychoactive compound in Ayahuasca 5-MeO-DMT = Psychedelic without visual distortions Bufotenine = Can cause severe discomfort and risks MAOI = Intensifies DMT effects when combined</p> Signup and view all the answers

    What should be avoided when using MAOIs with DMT?

    <p>All of the above</p> Signup and view all the answers

    The use of MAOIs is recommended for first-time DMT users.

    <p>False</p> Signup and view all the answers

    How long should one wait before attempting another DMT trip?

    <p>At least one hour</p> Signup and view all the answers

    What is the best method to identify the presence of DMT in the final product?

    <p>Distinct synthetic smell</p> Signup and view all the answers

    The evaporation process of the solvent can take less than one week.

    <p>False</p> Signup and view all the answers

    What should be done with the DMT while smoking it to avoid direct contact with the flame?

    <p>Heat the glass that holds the DMT instead of the DMT itself.</p> Signup and view all the answers

    You can get __________ doses from 30g of mimosa hostilis root-bark assuming best yields.

    <p>5-6</p> Signup and view all the answers

    Match the following substances with their usage in the extraction process:

    <p>Mimosa hostilis root-bark = Primary material for extraction Red Devil Lye = Raises pH Lighter fluid = Solvent for extraction Coffee filter = Used for filtering solution</p> Signup and view all the answers

    What is a suggested way to reduce unpleasant traces of hydroxide in the final product?

    <p>Wash the DMT crystals in water</p> Signup and view all the answers

    It is recommended to wait until the end of evaporation to scrape the final product.

    <p>True</p> Signup and view all the answers

    What amount is considered a good starting amount to scrape from the baking pan?

    <p>About 25mg, the size of a pea.</p> Signup and view all the answers

    DMT may resemble anything from a sticky orangish goo to __________, depending on the procedure followed.

    <p>white or pale-orange crystals</p> Signup and view all the answers

    What is a recommended inhalation method when consuming DMT?

    <p>Slow &amp; steady, deep inhalation</p> Signup and view all the answers

    Which of the following plants has the highest percentage of NN-DMT reported?

    <p>Acacia simplicifolia bark</p> Signup and view all the answers

    DMT can be effectively consumed orally without any special preparation.

    <p>False</p> Signup and view all the answers

    What is the alkaloid content of Pilocarpus organensis listed in the information?

    <p>1.06% 5-MeO-DMT</p> Signup and view all the answers

    The plant __________ hostilis root bark contains 0.57% NN-DMT.

    <p>Mimosa</p> Signup and view all the answers

    Match the following plants with their reported NN-DMT contents:

    <p>Acacia bark = 0.71% NN-DMT Desmanthus illinoensis root (bark) = 0.34% NN-DMT Phalaris arundinacea = 0.060% NN-DMT Psychotria species = 0.200% NN-DMT</p> Signup and view all the answers

    What percentage of 5-OH-DMT is reported in Phalaris tuberosa?

    <p>0.005%</p> Signup and view all the answers

    NN-DMT is the only psychoactive compound found in the listed plants.

    <p>False</p> Signup and view all the answers

    How should DMT be consumed to experience its effects?

    <p>It must be smoked in its freebase form.</p> Signup and view all the answers

    What is the primary concern when handling methylene chloride?

    <p>May cause blindness</p> Signup and view all the answers

    The best way to prepare plant material is to blend it without any freezing.

    <p>False</p> Signup and view all the answers

    What type of protective equipment should be worn when handling hazardous materials?

    <p>Goggles and gloves</p> Signup and view all the answers

    The process of pulvarizing plant material involves repeatedly freezing and _____ it.

    <p>thawing</p> Signup and view all the answers

    Match the items with their corresponding prices:

    <p>Naphtha = $5 Coffee filters = $2 Evaporating dish = $10 Glass pipette = $4</p> Signup and view all the answers

    Which of the following items is recommended for extracting solvents?

    <p>Glass jars with lids</p> Signup and view all the answers

    Methylene chloride poses a minimal risk if used properly.

    <p>False</p> Signup and view all the answers

    What is the recommended technique for grinding the plant material to optimize yields?

    <p>Freeze and thaw repeatedly</p> Signup and view all the answers

    The primary reason for keeping the plant material _____ during blending is to produce a finer texture.

    <p>frozen</p> Signup and view all the answers

    Which plant is mentioned as requiring specific treatment for proper preparation?

    <p>Phalaris arundinacea</p> Signup and view all the answers

    What primary substance is typically extracted from mimosa hostilis root-bark?

    <p>N,N-Dimethyltryptamine (DMT)</p> Signup and view all the answers

    The effects of DMT are typically refreshing and invigorating.

    <p>False</p> Signup and view all the answers

    What is one common concern associated with the consumption of Bufotenine?

    <p>Toxicity</p> Signup and view all the answers

    DMT is extracted from various ______ materials.

    <p>plant</p> Signup and view all the answers

    Match the following authors with their respective works:

    <p>Jim DeKorne = Psychedelic Shamanism Jonathan Ott = Ayahuasca Analogues: Pangaen Entheogens Alexander Shulgin = Tryptamines I Have Known And Loved</p> Signup and view all the answers

    What was done to the cotton T-shirt filter during the filtering process?

    <p>It was twisted to squeeze remaining liquid</p> Signup and view all the answers

    The naphtha layer was kept in the jar after shaking for 24 hours.

    <p>False</p> Signup and view all the answers

    How long was the jar left to sit in warm water after adding the acidic solution?

    <p>30 minutes</p> Signup and view all the answers

    The solution was strained _____ times through coffee filters.

    <p>3</p> Signup and view all the answers

    Match the jars with their respective contents or actions:

    <p>Jar A = Empty jar before filtering Jar B = Contains root-bark and liquid Jar C = Filled with acidic water Jar D = Filled with filtered liquid</p> Signup and view all the answers

    What was the purpose of using a funnel during the filtering process?

    <p>To assist in the placement of the filter</p> Signup and view all the answers

    Thick gloves are recommended when handling chemicals in this process.

    <p>True</p> Signup and view all the answers

    What was used to siphon the bottom layer out of the jar?

    <p>Turkey baster</p> Signup and view all the answers

    After shaking the jar, a layer of _____ scum is produced on top.

    <p>translucent pink</p> Signup and view all the answers

    What was added to Jar C before filtering?

    <p>5ml of muratic acid</p> Signup and view all the answers

    What is the purpose of basifying the solution?

    <p>To transform the alkaloid into its free base form</p> Signup and view all the answers

    Ammonium hydroxide is the preferred base to use for basifying the solution.

    <p>False</p> Signup and view all the answers

    What is a suitable measurement for creating a basic mixture for basifying?

    <p>5g of lye mixed with 95g of water</p> Signup and view all the answers

    Using a pipette, the solvent layer is removed and discarded during the __________ process.

    <p>defatting</p> Signup and view all the answers

    Match the following components with their corresponding actions:

    <p>Pipette = Remove solvent layer Separatory funnel = Separate two solutions Jar A = Contains water and lye mixture Jar B = Contains warm naphtha</p> Signup and view all the answers

    How long should you shake Jar B after adding warm naphtha?

    <p>5 minutes</p> Signup and view all the answers

    A DIY separatory funnel can be created using a Ziplock baggie.

    <p>True</p> Signup and view all the answers

    What is the suggested pH level for Jar A after mixing the water and lye?

    <p>approximately 12</p> Signup and view all the answers

    The formed layers in the separatory funnel can be drained through the __________.

    <p>bottom faucet</p> Signup and view all the answers

    Which of the following is NOT recommended when using lye?

    <p>Mix lye directly in a concentrated form</p> Signup and view all the answers

    What process was done on Day 19 after the aqueous solution collection from jar A?

    <p>Material was filtered again into jar B.</p> Signup and view all the answers

    The pH of the mixture reached approximately 11 after adding the 5% base solution.

    <p>True</p> Signup and view all the answers

    What was the main solvent used during the extraction process?

    <p>Naphtha</p> Signup and view all the answers

    The combined solvent fractions were poured into a glass baking dish for _______ before being scraped clean.

    <p>evaporation</p> Signup and view all the answers

    Match the days with the significant actions that took place in the experiment:

    <p>Day 12 = Funnel and cotton ball set up for filtering Day 19 = Aqueous solution collected from jar A Day 28 = 5% base solution added Day 39 = Combined fractions poured for evaporation</p> Signup and view all the answers

    Which of the following statements about DMT is true?

    <p>DMT can be extracted from common plant materials.</p> Signup and view all the answers

    DMT is a social drug that is recommended for inexperienced users.

    <p>False</p> Signup and view all the answers

    What is one reason why educating oneself about DMT is emphasized?

    <p>To make one more competent and prepared in its use.</p> Signup and view all the answers

    DMT is not for the inexperienced, nor is it recommended for those looking for another __________.

    <p>high</p> Signup and view all the answers

    Match the following substances with their characteristics:

    <p>DMT = Powerful hallucinogen LSD = Synthetic psychedelic Psilocybin = Magic mushrooms compound Bufotenine = Toad venom derivative</p> Signup and view all the answers

    What condition has been associated with abnormal levels of DMT in individuals?

    <p>Schizophrenia</p> Signup and view all the answers

    DMT can be synthesized safely in a laboratory.

    <p>False</p> Signup and view all the answers

    Name one method of sourcing DMT mentioned in the content.

    <p>Extracting from common plant materials.</p> Signup and view all the answers

    What is the recommended maximum temperature when heating the solution?

    <p>50° C</p> Signup and view all the answers

    Squeezing the root-bark contents after filtration removes remaining juices.

    <p>True</p> Signup and view all the answers

    What should be used to plug the bottom of the funnel during filtration?

    <p>cotton balls or cotton cloth</p> Signup and view all the answers

    Do not allow the solution to ______ during the heating process.

    <p>evaporate</p> Signup and view all the answers

    Match the following steps with their respective descriptions:

    <p>Step 1 = Heat muratic acid for 15-30 minutes Step 2 = Simmer weaker acids overnight Step 3 = Collect additional extractions Step 4 = Squeeze root-bark material after filtering</p> Signup and view all the answers

    What is an effective way to improve the filtration method?

    <p>Use a vacuum filter</p> Signup and view all the answers

    The initial extraction is considered the least important in the process.

    <p>False</p> Signup and view all the answers

    What should be done to allow the solution to cool safely?

    <p>Turn off the heat source and let it return to room temperature.</p> Signup and view all the answers

    For the filtration process, the thinner parts of the solution should be filtered ______ the bulkier components.

    <p>first</p> Signup and view all the answers

    What should be done after pouring the contents of Jar B into Jar C?

    <p>Squeeze the filter and collect remaining juices</p> Signup and view all the answers

    What is the primary hazard associated with methylene chloride?

    <p>Cancer risk</p> Signup and view all the answers

    Using a blender to pulverize plant material is the only method for achieving fine powder.

    <p>False</p> Signup and view all the answers

    What type of jars work best for storing the extracted material?

    <p>Thick canning jars or pickle jars</p> Signup and view all the answers

    The process of _____ and thawing plant material several times improves its yield.

    <p>freezing</p> Signup and view all the answers

    Match the item to its cost:

    <p>Naphtha = $5 Goggles and gloves = $10 Evaporating dish = $10 Glass pipette = $4</p> Signup and view all the answers

    What is the main reason for using protective gear when handling methylene chloride?

    <p>It prevents skin and eye irritation</p> Signup and view all the answers

    The freezing process aids in better extraction yields from plant material.

    <p>True</p> Signup and view all the answers

    What is the cost of the coffee filters and cotton swabs/cloth?

    <p>$2</p> Signup and view all the answers

    The preferred type of grass mentioned for the extraction process is _____ arundinacea.

    <p>Phalaris</p> Signup and view all the answers

    What is the approximate total cost of materials listed for the extraction process?

    <p>$100</p> Signup and view all the answers

    What is the significance of waiting at least one hour before attempting another DMT trip?

    <p>To allow the body to fully process the initial dose</p> Signup and view all the answers

    Taking NN-DMT with MAOIs is generally considered safe for beginners.

    <p>False</p> Signup and view all the answers

    What physical discomforts can Bufotenine cause?

    <p>Circulatory distress and nausea</p> Signup and view all the answers

    The recommended starting amount of Mimosa hostilis root-bark is _____ grams.

    <p>30</p> Signup and view all the answers

    Match the following substances with their effects:

    <p>NN-DMT = Psychedelic effects with visual distortions 5-MeO-DMT = Psychedelic effects without visual distortions Bufotenine = Severe physical discomfort MAOIs = Intensify effects of NN-DMT</p> Signup and view all the answers

    Which solvent is specified for use in the DMT extraction process?

    <p>Naphtha</p> Signup and view all the answers

    The body quickly builds a tolerance for DMT.

    <p>True</p> Signup and view all the answers

    What should be tested with solvents to avoid adverse reactions?

    <p>Non-glass materials</p> Signup and view all the answers

    5-MeO-DMT is taken at _____ the dose of NN-DMT.

    <p>1/4</p> Signup and view all the answers

    What is a dangerous effect of using MAOIs with other drugs?

    <p>Serious health problems and potential death</p> Signup and view all the answers

    Study Notes

    N,N-Dimethyltryptamine (DMT)

    • Chemical name: N,N-Dimethyl-1H-indole-3-ethanamine
    • Alternative names: 3-[2-(dimethylamino)ethyl]indole, DMT
    • Chemical formula: C₁₂H₁₆N₂
    • Molecular weight: 188.27 g/mol
    • Melting point: 44.6-44.8 °C (crystals)
    • Boiling point: 60-80 °C (crystals)
    • Controlled substance (hallucinogen) under U.S. Code of Federal Regulations, Title 21 Part 1308.11 (1985)

    DMT Dosages

    • Intravenous: 4-30 mg
    • Smoking: 60-100 mg
    • Subcutaneous: 60-100 mg
    • Intramuscular: 60-100 mg
    • Oral: >350 mg (requires MAOIs, but not recommended for first-time users)

    DMT Extraction and Use

    • Mimosa hostilis root bark is a common source for DMT extraction.
    • Naphtha is used as a solvent in extraction process.
    • The extraction process involves several steps including acidification, basification, and solvent extraction, with final product purification.
    • DMT has a distinct synthetic smell, likened to manufactured plastics.
    • A 25mg starting dose (about the size of a pea) is suggested for smoking. Multiple doses may be needed to achieve the desired effect. Avoid touching the DMT with the flame when smoking.
    • Tolerance builds quickly; allow at least one hour between doses.
    • 5-MeO-DMT: Psychedelic, lower dosage required than N,N-DMT, lacks visual distortions of N,N-DMT.
    • 5-OH-DMT (Bufotenine): Can cause severe physical and psychological distress, even death.

    MAOIs (Monoamine Oxidase Inhibitors)

    • Intensify and prolong the effects of DMT. However, combining MAOIs with other drugs is dangerous and may be fatal.
    • MAOIs increase levels of serotonin, norepinephrine, and dopamine by inhibiting their metabolism.
    • Unmetabolized tyramine increases blood tyramine levels.

    DMT Extraction Lab Notes (Lab #1)

    • Used 25g Mimosa hostilis root bark, muratic acid, pH papers, lye, lighter fluid, coffee filters, cotton t-shirt, plastic funnel, pickle jars, baking dish, turkey baster, and cooking pot.
    • Root bark was powdered using a blender.
    • Acidified water had a pH of 1.
    • Mixture developed three layers after shaking: pink foam (top), dark red/black liquid (middle), and lighter red sediment (bottom).
    • Heating the mixture was implemented to speed the process.

    Additional Resources

    • Psychedelic Shamanism: The Cultivation, Preparation and Shamanic Use of Psychotropic Plants by Jim DeKorne (1994)
    • Ayahuasca Analogues: Pangaen Entheogens by Jonathan Ott (1994)
    • Tryptamines I Have Known And Loved: The Chemistry Continues (Part 2) by Alexander and Ann Shulgin (Journal of Pharmaceutical Sciences, Vol. 56, page 1526)
    • Erowid website (various images and information)
    • Rhodium site (technical information)

    DMT Extraction and Use

    • DMT is a powerful hallucinogen not detected in standard drug tests.
    • It's naturally occurring in the body and found in elevated levels in individuals with schizophrenia.
    • DMT is rarely sold, synthesized, or used recreationally; it's easily extracted from plants.
    • It's not recommended for inexperienced users or those seeking a casual high.
    • Even experienced psychedelic users can have negative first-time experiences.

    DMT Dosage and Effects

    • Oral DMT ingestion is possible when mixed with MAOIs, but not recommended for first-time users.
    • Tolerance builds quickly; doses must be within 60 seconds for optimal effect.
    • At least a one-hour gap should exist between DMT trips.
    • 5-MeO-DMT, a related compound, has psychedelic effects without the visual distortions of N,N-DMT; its dose is 1/4 of N,N-DMT.
    • 5-OH-DMT can cause severe physical and psychological distress, including circulatory issues, nausea, panic, and potentially fatality.
    • MAOIs intensify and prolong N,N-DMT effects but can cause serious health problems or death when combined with other drugs. They inhibit the metabolism of serotonin, norepinephrine, and dopamine, increasing their levels and also leading to increased blood tyramine levels.

    Mimosa Hostilis Root-Bark Extraction Procedure

    • Mimosa hostilis root bark is used for a pure N,N-DMT product, avoiding 5-MeO-DMT and 5-OH-DMT.
    • Naphtha is used as a solvent.

    Materials Needed

    • Mimosa hostilis root bark (30g suggested)
    • Muratic acid (pool acid)
    • pH papers (litmus papers)
    • Lye (Red Devil brand)

    Extraction Steps

    • Step 1: Select Mimosa hostilis root bark.
    • Step 2: Acidify the root bark using muratic acid (15-30 minutes heating, longer for weaker acids; maintain temperature below 50°C/122°F). This makes tryptamines water-soluble salts.
    • Step 3: Filter the mixture (cotton filter recommended), pressing out remaining juices. Repeat Step 2 two more times, increasing reaction time for subsequent extractions.
    • Step 4: Combine solvent fractions from extractions, then allow the solvent to evaporate (up to one week). This leaves behind DMT. About 25mg is an appropriate starting dose.

    Notes and Safety

    • Test non-glass materials with solvents to avoid reactions.
    • Gentle heating using a double boiler is recommended to prevent breakage.
    • Proper safety equipment (gloves, eye protection) should be used when handling chemicals.
    • DMT is illegal in the USA and extraction is presented for educational purposes only.
    • The final product may look like an orangish goo or pale-orange crystals, and has a distinct synthetic smell.

    Lab Notes and Variations

    • Vacuum filtration can speed up the process.
    • Washing DMT crystals in water may reduce hydroxide traces.
    • Water can be added to the solvent evaporating dish to aid in carrying off hydroxide.

    Lab Report Example

    • One lab report details an experiment using 25g of Mimosa hostilis root bark, pool acid, lighter fluid, and coffee filters; it describes a multi-day process involving multiple filtrations, acidification, and naphtha extraction, resulting in a final product. The process included siphoning and careful separation of layers.

    Mimosa Hostilis Root-Bark Extraction

    • Acidification (Step 2): Two jars (A and B) are prepared. Jar A contains acidified water (pH 2) using vinegar, muriatic acid, or other strong acids. Always add acid to water, not vice versa. pH testing is crucial, using pH paper or a meter; red cabbage or beet juice can provide a rough estimate.

    • Alkaloid Conversion (Step 3): Acidified water from Jar A is added to Jar B containing powdered root-bark to convert alkaloids into water-soluble salts. Gentle heating (below 50°C) facilitates this process; weaker acids require longer heating times. Allow 24 hours for the initial reaction.

    • Filtration (Step 4): The solution from Jar B is filtered through a cotton filter into Jar C, squeezing the root bark to extract remaining liquid. Multiple filtrations improve the purity of the product. A vacuum filter can accelerate the process.

    • Multiple Extractions (Step 5): Steps 2, 3, and 4 are repeated twice more for optimal yield, increasing reaction time for subsequent extractions.

    • Basification (Step 5): Lye solution is gradually added to the filtered solution until the pH reaches 11-12, turning the solution gray, then black. The solution will heat up. This converts the salts back to freebase alkaloids soluble in non-polar solvents.

    • Emulsion Formation (Step 9): A non-polar solvent (e.g., naphtha or dichloromethane) is added, creating an emulsion. Stirring intensity affects separation time; gentle stirring is recommended. Salt addition and extra solvent can aid emulsion separation if necessary. Naphtha emulsions require more time to separate than DCM emulsions.

    • Final Extraction and Evaporation (Step 10): Steps 7 and 9 are repeated twice. After the final extraction, the solution is filtered multiple times (cotton and coffee filters used) to separate the target alkaloids. The naphtha layer is carefully removed, leaving behind the aqueous solution and impurities. The removal of the naphtha layer is described as a lengthy multi-day process involving multiple filtrations and careful adjustments to the pH level to separate the desired components from the unwanted materials; several methods are described to aid the process.

    Additional Notes:

    • Safety precautions, including gloves and eye protection, are emphasized.
    • The process is described in detail, including the use of pickle jars, cotton filters, and various methods to improve yield and purity.
    • The description of the process includes observations of the color and viscosity changes during various stages of the extraction.
    • Specific techniques and materials are suggested throughout the extraction process, including the use of a double boiler for heating the acidic solution and the use of a water vacuum filter to expedite the filtering process.
    • Time requirements are indicated for various stages, suggesting a process that spans several days.

    N,N-Dimethyltryptamine (DMT)

    • Chemical name: N,N-Dimethyl-1H-indole-3-ethanamine
    • Alternative names: 3-[2-(dimethylamino)ethyle]indole, DMT
    • Chemical formula: C₁₂H₁₆N₂
    • Molecular weight: 188.27 g/mol
    • Melting point: 44.6-44.8 °C (crystals)
    • Boiling point: 60-80 °C (crystals)
    • Dosages: 4-30mg (IV), 60-100mg (smoking, subcutaneous, intramuscular), >350mg (oral)
    • Controlled substance (hallucinogen)

    DMT Extraction Method

    • Step 2: Acidify Water to pH 2
      • Use 2 pickle jars, labelled A and B.
      • Fill Jar A with water (~500ml) and add 1/2 teaspoon (~2ml) of acid (vinegar, muriatic acid, or HCl/H₂SO₄).
      • Test pH using pH paper or a meter; adjust by adding more water if the pH is not 2.
      • Alternative pH indicators: red beets or red cabbage juice.
    • Step 3: Convert Alkaloids to Salts
      • Transfer acidified water from Jar A to Jar B (covering root bark).
      • This converts alkaloids to salts.
      • Remove and discard the solvent layer; repeat twice.
      • Separatory funnel or a Ziploc bag can be used for layer separation.
    • Step 7: Prepare to Basify
      • Add 100ml of warm naphtha to Jar B and shake for 5 minutes.
    • Step 8: Basify to pH 11
      • Basify solution using lye (NaOH) to “unhook” salts and make alkaloids insoluble in water.
      • Mix 5g lye with 95g water (to avoid localized pH spikes).
      • Gradually add the lye solution to Jar B, checking pH until approximately 11-12 is reached.
      • Heat and stir the mixture; let it rest.
    • Further Steps (Days 5-14):
      • Filtration and straining of the mixture (using cotton shirts or coffee filters).
      • Multiple additions of naphtha, shaking, and resting.
      • Repeated adjustments of pH using lye solution.
      • Observation of layers and emulsions.
      • Addition of salt to aid separation.
      • Final filtration and separation of the naphtha layer containing DMT.

    Safety Precautions

    • Always add acid to water, not water to acid.
    • Wear appropriate protective gear (gloves, eye protection) when working with acids and lye.
    • Lye is caustic and can react violently; handle with care and dilute before use.

    Extraction Phase 1

    • Shake Jar B four times daily for one week, filtering through a cotton filter each time.
    • Collect the acidic contents in Jar C.
    • Clean Jar A and Jar B and dispose of root bark after three filtration cycles.
    • After all three extraction phases, filter Jar C's contents using a paper coffee filter.

    Extraction Phase 2 (Filtration)

    • Strain Jar C contents through several paper filters into Jar B.
    • Clean Jar C.
    • Repeat as needed to remove particulates.
    • Most alkaloids convert to salts in the first phase.
    • Subsequent phases extract additional alkaloids over longer periods (third phase can be shortened to 1-2 days but has lower yield).

    Defatting the Solution

    • Defatting removes oils, fats, and unwanted substances, improving yield.
    • DMT salts are insoluble in non-polar solvents, except DMT acetate (soluble in chloroform and DCM).
    • If using white vinegar (acetic acid), use naphtha or ether for defatting to avoid extracting DMT acetate.
    • Defatting may be unnecessary for mimosa hostilis root bark, but recommended for chlorophyll-containing plant material.
    • Test solvents by evaporating a sample to check for residues.

    Defatting Solvents

    • Naphtha: Coleman fuel, VM&P naphtha, Zippo fluid; evaporates to check purity and is selective for alkaloids; rises to the top.
    • Methylene Chloride (DCM): Adhesive solvent (distill from paint strippers before use); sinks to the bottom; may cause cancer and blindness.
    • Ether: Found in engine starting fluid; extremely volatile; floats to the top.
    • Chloroform: Available online; harsh on organics; boiling point 35-65°C (95-149°F); sinks to the bottom.

    Defatting Process

    • Add 50-100ml naphtha (10-15% of acidic solution volume) to Jar B.
    • Shake vigorously for 20 minutes.
    • Allow to separate into layers (~24-48 hours).
    • Remove and discard the top (naphtha) layer using a pipette or turkey baster.
    • Repeat twice.
    • Separatory funnels or modified Ziploc bags aid layer separation.

    Preparing to Basify

    • Add 100ml warm naphtha to Jar B.
    • Shake for 5 minutes.

    Basifying to pH 11

    • Basifying "unhooks" the salts, transforming alkaloids to their "free base" form insoluble in water.
    • This allows extraction with the organic solvent.
    • Use a diluted lye solution (5g lye in 95g water) to avoid destroying alkaloids.

    Basification Process

    • Mix 95ml water and 5g lye in Jar A; confirm pH ~12.
    • Slowly add Jar A solution to Jar B.
    • Additional naphtha can be added and heated, mixing carefully by slowly tipping the jar.

    Lab Notes: Phalaris Arundinacea Extraction (Lab #2)

    • 25g of dry Phalaris arundinacea (contains 5-MeO alkaloids) was used.
    • The grass was difficult to pulverize, requiring freezing, blending, and repeated water additions.
    • 5ml muriatic acid was added to 500ml water in Jar B to cover 25g of pulverized grass.
    • The mixture was shaken daily from Day 3 to Day 11.
    • Content was separated by filtration through cotton balls to achieve an aqueous solution.
    • Plant matter was reused with additional acid.
    • The process was repeated.
    • The remaining plant matter was discarded.
    • The solution strained 3 times through coffee filters.
    • Naphtha was used for extraction.
    • Lye crystals and water solution was used for basification.
    • The end product was collected after evaporation of the naphtha.

    N,N-Dimethyltryptamine (DMT) Properties

    • Chemical Name: N,N-Dimethyl-1H-indole-3-ethanamine
    • Alternative Names: 3-[2-(dimethylamino)ethyle]indole, DMT
    • Chemical Formula: C₁₂H₁₆N₂
    • Molecular Weight: 188.27 g/mol
    • Melting Point: 44.6-44.8°C (crystals)
    • Boiling Point: 60-80°C (crystals)
    • Dosage: 4-30mg (IV), 60-100mg (smoked/SC/IM), >350mg (oral)
    • Controlled substance (hallucinogen)

    DMT and Traditional Rituals

    • Modern reduction of ritual has diminished access to epiphanic experiences.
    • Shamans understand the importance of intense psychological experiences for spiritual growth.
    • Chemical induction of spiritual breakthroughs may be seen as circumventing necessary trials.
    • Many readily available plants contain DMT.

    Plant Sources of DMT, 5-MeO-DMT, and 5-OH-DMT

    • Alkaloid content varies depending on growing conditions.
    • Data represent (mg) per (100g) raw dried plant and percent of total plant weight:
      • Acacia bark: 0.71% N,N-DMT
      • Acacia maidenii bark: 0.36% N,N-DMT
      • Acacia simplicifolia bark: 0.86% N,N-DMT
      • Mimosa hostilis root bark: 0.57% N,N-DMT
      • Virola shoots & flowers: 0.44% N,N-DMT
      • Desmanthus illinoensis root bark: 0.34% N,N-DMT
      • Pilocarpus organensis: 1.06% 5-MeO-DMT
      • Phalaris tuberosa: 0.10% N,N-DMT, 0.022% 5-MeO-DMT, 0.005% 5-OH-DMT
      • Phalaris arundinacea: 0.060% N,N-DMT, unknown 5-MeO-DMT content
      • Psychotria species (average): 0.200% N,N-DMT
    • DMT is highly hallucinogenic.
    • Oral DMT is inactive unless combined with MAOIs (not recommended for first-time users).
    • Rapid tolerance develops; doses must be taken within 60 seconds for optimal effect.
    • At least a 1-hour break between trips is recommended.
    • 5-MeO-DMT is psychedelic without the visual distortions of N,N-DMT. Dosage is 1/4 that of N,N-DMT; it overwhelms N,N-DMT's effects.
    • 5-OH-DMT can be dangerous, causing severe physical and psychological distress and potentially death.
    • MAOIs intensify and prolong N,N-DMT effects but are not recommended due to potential health risks. They inhibit the metabolism of serotonin, norepinephrine, and dopamine, and can cause increased levels of tyramine in the blood.

    DMT Extraction Procedure using Mimosa Hostilis

    • Uses Mimosa hostilis root bark and naphtha as solvent.
    • Materials:
      • Mimosa hostilis root bark (30g suggested)
      • Muratic acid (pool acid)
      • pH papers (litmus papers)
      • Lye (Red Devil drain cleaner)
    • A separatory funnel (or improvised baggie method) is useful for separating solutions.
    • Testing non-glass materials with solvents beforehand is recommended to avoid reactions.

    Basification and Extraction steps

    • Basification "unhooks" the salt and makes the alkaloid soluble in the organic solvent.
    • Lye (NaOH) is used to basify to pH 11. Diluting the lye is important to prevent damaging the alkaloids.
    • A 5g lye/95g water mixture is suggested.
    • The process involves shaking, warming, and allowing the solution to separate into layers. Filtration may be necessary to improve separation. Adding salt can sometimes aid separation.

    Detailed Process Observations (Day 10-14)

    • Day 10: Initial basification changed solution color from burgundy red to grayish blue, reaching pH ~11-12 after 10 teaspoons of base solution addition.
    • Days 11-12: No layer separation; more solvent added.
    • Day 13: No change; salt added, no effect.
    • Day 14: pH of aqueous solution ~9-10; additional base solution added which resulted in layer separation. Mixture was filtered and naphtha layer saved.

    N,N-Dimethyltryptamine (DMT)

    • Chemical Name: N,N-Dimethyl-1H-indole-3-ethanamine
    • Alternative Names: 3-[2-(dimethylamino)ethyle]indole, DMT
    • Chemical Formula: C₁₂H₁₆N₂
    • Molecular Weight: 188.27 g/mol
    • Melting Point: 44.6-44.8 °C (crystals)
    • Boiling Point: 60-80 °C (crystals)
    • Dosages: 4-30mg (intravenously), 60-100mg (smoking, subcutaneously, intramuscularly), >350mg (orally)
    • A controlled substance (hallucinogen) under U.S. Code of Federal Regulations, Title 21 Part 1308.11 (1985)
    • Naturally occurs in the human body and has been found at abnormal levels in individuals with schizophrenia.
    • Not typically sold by dealers or synthesized, but readily extractable from various plants.

    DMT Extraction

    • Plant Selection: Several plants contain DMT, including Acacia species, Mimosa hostilis, Virola species, Desmanthus illinoensis, Pilocarpus organensis, and Phalaris species. Alkaloid content varies depending on growing conditions.
    • Extraction Process: A detailed ten-step process is described, involving steps such as defatting, basification (using lye or NaOH), and solvent extraction (using naphtha).
    • Basification: This step uses lye (NaOH) to change the alkaloid into its freebase form, making it soluble in organic solvents. Diluting the base prevents damaging the alkaloids.
    • Solvent Evaporation: After extraction, the solvent is evaporated, leaving behind a residue that may be a sticky substance or crystals. Evaporation can take up to a week.
    • Yields: From 30g of Mimosa hostilis root-bark, 5-6 doses (approx. 275mg) of DMT are possible, under optimal conditions. The final product has a distinct synthetic smell.
    • Safety Precautions: Lye is caustic and requires careful handling. The process involves the use of flammable solvents and should be performed with appropriate safety measures. DMT is illegal in the USA.

    Additional Notes

    • DMT is not orally active (unless in an ayahuasca brew); it must be smoked in its freebase form.
    • Separatory funnels aid in separating solutions. Improvised funnels can be made using plastic bags.
    • The final product may contain trace amounts of hydroxide, which some find unpleasant. Washing DMT crystals in water can help reduce this.
    • All information is presented for educational purposes only.

    Plant Alkaloid Content

    • Acacia bark contains 0.71% N,N-dimethyltryptamine (NN-DMT).
    • Acacia maidenii bark contains 0.36% NN-DMT.
    • Acacia simplicifolia bark contains 0.86% NN-DMT.
    • Mimosa hostilis root (bark) contains 0.57% NN-DMT.
    • Virola shoots & flowers contain 0.44% NN-DMT.
    • Desmanthus illinoensis root (bark) contains 0.34% NN-DMT.
    • Pilocarpus organensis contains 1.06% 5-MeO-DMT.
    • Phalaris tuberosa contains 0.10% NN-DMT, 0.022% 5-MeO-DMT, and 0.005% 5-OH-DMT.
    • Phalaris arundinacea contains 0.060% NN-DMT and an unknown amount of 5-MeO-DMT.
    • Psychotria species (average) contains 0.200% NN-DMT.
    • Alkaloid content varies depending on growing conditions.
    • Many of these plants are readily available, both wild and commercially (online).

    DMT Extraction

    • DMT is a potent hallucinogen, inactive orally unless in an ayahuasca brew; it must be smoked in its freebase form for effects.
    • A separatory funnel (or a modified Ziploc bag) is used to separate solutions into distinct layers.
    • Naphtha is used as a solvent, warmed before use.
    • Basifying the solution to pH 11 with NaOH (lye) transforms the alkaloid into its freebase form.
    • A mixture of 5g lye in 95g water is recommended for basification, to prevent damage to alkaloids.
    • The solvent is evaporated, leaving behind a residue (sticky goo to crystals).
    • The final product may contain trace amounts of hydroxide, which can be lessened by washing with water.
    • DMT has a distinct synthetic smell, similar to some plastics.
    • A good starting dose is around 25mg (pea-sized).

    Lab Notes & Procedures (LAB #1)

    • 25g of mimosa hostilis root-bark was used.
    • Materials included pool acid, litmus paper, Red Devil lye, lighter fluid, coffee filter, cotton t-shirt, plastic funnel, and pickle jars.
    • The process involved multiple steps of acidification, filtration, solvent extraction (with naphtha), and evaporation.
    • The final product was initially a caramel-like substance which later showed a more crystalline structure.

    Lab Notes & Procedures (LAB #2)

    • 25g of Phalaris arundinacea (containing 5-MeO alkaloids) was used.
    • The plant material was challenging to pulverize, requiring freezing and blending. Water was added during the blending process to aid in pulverization.
    • The process involved freezing and thawing the plant material multiple times over a 24 hour period.
    • 5ml of muriatic acid was added to a pickle jar containing roughly 500ml of water.

    DMT and Analogues

    • Oral DMT administration requires MAOIs, but this is not recommended for first-time users.
    • Tolerance builds rapidly; doses must be taken within 60 seconds for optimal effects. At least a one-hour break is recommended between trips.
    • 5-MeO-DMT produces psychedelic effects without the visual distortions of N,N-DMT. It's taken at 1/4 the dose of N,N-DMT and can overpower it.
    • Bufotenine (5-OH-DMT) can cause severe physical and psychological distress, including circulatory issues, nausea, and potentially death.
    • MAOIs intensify and prolong N,N-DMT effects, but this combination is highly dangerous. MAOIs inhibit the metabolism of serotonin, norepinephrine, and dopamine, leading to increased levels of these neurotransmitters. They also prevent tyramine metabolism, causing elevated blood tyramine levels.

    Mimosa Hostilis Extraction of N,N-DMT

    • Mimosa hostilis root bark is used for the extraction of pure N,N-DMT, avoiding the negative effects of 5-MeO-DMT and 5-OH-DMT.
    • Naphtha is used as a solvent. Other solvents (DCM, methanol) have different properties and require adjusted procedures.
    • Materials include Mimosa hostilis root bark, muratic acid, pH papers, lye, and a non-reactive container. Materials should be tested and checked for compatibility with the solvent used.
    • The process involves adjusting the pH to ~11-12 using lye, then separating using a non-polar solvent. Emulsions can form and might take time to separate. Techniques to resolve emulsions are described.
    • Repeated extraction steps are necessary to maximize yield.
    • The solvent is evaporated; the remaining substance is DMT, potentially appearing as a sticky goo or crystals. A starting dose of about 25mg is suggested. The smell is noted as a distinctive synthetic smell, almost like plastics.
    • Post-evaporation, DMT may contain traces of hydroxide which some find unpleasant. Washing with water and re-evaporation helps reduce this.

    Extraction Lab Notes

    • Lab #1: Used 25g of Mimosa hostilis root bark and lighter fluid as solvent. Slow, end-over-end mixing is suggested to reduce emulsion formation time. Evaporation yielded crystals that dissolved into a substance described as caramel-like, later drying into crystals.
    • Lab #2: Used 25g of Phalaris arundinacea (containing 5-MeO alkaloids). The grass was difficult to process, requiring freezing, thawing, and blending. The extraction steps are similar but used cotton balls instead of coffee filter and t-shirt for filtering.

    Additional Notes

    • Several photos of DMT crystals and Mimosa hostilis root bark are referenced, along with links to further information.
    • References to books and online resources for psychedelic plants and chemistry are provided.

    Plant Alkaloid Content

    • Acacia bark contains 0.71% NN-DMT.
    • Acacia maidenii bark contains 0.36% NN-DMT.
    • Acacia simplicifolia bark contains 0.86% NN-DMT.
    • Mimosa hostilis root (bark) contains 0.57% NN-DMT.
    • Virola shoots & flowers contain 0.44% NN-DMT.
    • Desmanthus illinoensis root (bark) contains 0.34% NN-DMT.
    • Pilocarpus organensis contains 1.06% 5-MeO-DMT.
    • Phalaris tuberosa contains 0.10% NN-DMT, 0.022% 5-MeO-DMT, and 0.005% 5-OH-DMT.
    • Phalaris arundinacea contains 0.060% NN-DMT and an unknown amount of 5-MeO-DMT.
    • Psychotria species (average) contain 0.200% NN-DMT.
    • Alkaloid content varies depending on growing conditions.

    DMT Extraction Materials and Costs

    • Naphtha (Zippo lighter fluid): ~$5
    • Coffee filters and cotton swabs/cloth: ~$2
    • Funnel: ~$2
    • 3 labeled glass jars with lids: ~$3
    • Evaporating dish (glass baking pan): ~$10
    • Glass pipette (turkey baster): ~$4
    • Goggles and gloves: ~$10
    • Total estimated cost: ~$40

    DMT Extraction: Hazards and Precautions

    • Methylene chloride is a suspect carcinogen.
    • It causes skin and eye irritation, respiratory tract irritation, and may affect blood cells and the central nervous system.
    • Avoid breathing vapor or mist.
    • Handle with caution and use appropriate personal protective equipment (PPE).
    • Lye (NaOH) is caustic and can react violently; use caution.

    DMT Extraction: Plant Preparation

    • Grind plant material into a fine powder.
    • Repeated freezing and thawing improves yield, especially for strong plants like Phalaris arundinacea.
    • Mimosa hostilis root-bark is easily pulverized in a blender.

    DMT Extraction: Steps and Procedures

    • Defatting: Use a solvent (e.g., naphtha) to remove unwanted fats and oils from plant material. Repeat the process multiple times.
    • Basification: Raise the pH of the solution to ~12 using a dilute lye solution (NaOH) to convert the alkaloid into its freebase form. This makes it soluble in the organic solvent.
    • Extraction: Use a solvent (e.g., warm naphtha) to extract the alkaloids from the basified solution. Shake vigorously for an extended period to maximize extraction.
    • Separation: Allow layers to separate; carefully remove the solvent layer containing the alkaloids.
    • Filtration: Filter the solution using coffee filters or other filtration methods to remove solid particles.
    • Acidification (optional): Acidify the aqueous solution to precipitate the alkaloids (requires additional chemicals).
    • Crystallization (optional): Further purification may be done to obtain DMT crystals.

    Additional Resources

    • Psychedelic Shamanism: The Cultivation, Preparation and Shamanic Use of Psychotropic Plants by Jim DeKorne (1994)
    • Ayahuasca Analogues: Pangaen Entheogens by Jonathan Ott (1994)
    • Tryptamines I Have Known And Loved: The Chemistry Continues (Part 2) by Alexander and Ann Shulgin (Journal of Pharmaceutical Sciences, Vol. 56, page 1526)
    • rhodium.lycaeum.org (for chemical information)
    • Erowid (for images and additional information)

    DMT: Extraction and Properties

    • DMT is a powerful hallucinogen related to LSD and psilocybin. It’s naturally occurring in the human body and some plants.
    • DMT is not detectable in standard drug tests.
    • Elevated DMT levels have been found in the body fluids of schizophrenic individuals.
    • DMT is rarely sold or synthesized, but easily extracted from plants.
    • It's not considered a "social drug," and inexperience or recreational use is discouraged due to its potent effects.
    • Even experienced psychedelic users can have frightening first-time experiences with DMT. Thorough research is crucial before use.
    • Oral DMT ingestion is possible when combined with MAOIs (Monoamine Oxidase Inhibitors), but it's not recommended for first-time users.
    • A DMT dose must be taken within 60 seconds for optimal effects; additional doses within the first minute won't enhance the trip. At least one hour should elapse between trips.
    • 5-MeO-DMT, another tryptamine, has psychedelic effects without the visual distortions of N,N-DMT. It’s taken at 1/4 the dose of N,N-DMT and overpowers it.
    • 5-OH-DMT (Bufotenine) can cause severe physical and psychological distress and is potentially fatal.
    • MAOIs intensify and prolong N,N-DMT's effects, posing significant health risks when combined with other drugs. MAOIs inhibit the metabolism of serotonin, norepinephrine, and dopamine. This leads to increased levels of those neurotransmitters as well as Tyramine, resulting in elevated tyramine levels in the blood.

    DMT Extraction from Mimosa Hostilis

    • This guide describes extracting N,N-DMT from Mimosa hostilis root bark using naphtha as a solvent, avoiding the potentially harmful 5-MeO-DMT and 5-OH-DMT.
    • The process uses common materials, costing roughly $100. It's essential to test non-glass materials for solvent compatibility.
    • Materials: Mimosa hostilis root bark (30g suggested), muriatic acid (pool acid), pH papers, lye, naphtha (Zippo lighter fluid), coffee filters/cotton, funnel, three labeled glass jars, evaporating dish (glass baking pan), glass pipette (turkey baster), goggles and gloves.
    • Step 1: Preparing Plant Material: Grind the Mimosa hostilis root bark into a fine powder. Freezing and thawing repeatedly can improve pulverization, especially for tougher plants like Phalaris arundinacea.
    • Step 2: Acidification: Mix the powdered plant material with muriatic acid in a jar. The weaker the acid, the longer the heating time, but don't boil (below 50°C/122°F). For muriatic acid, heat for 15-30 minutes; for weaker acids, simmer overnight. Allow 24 hours for the initial reaction.
    • Step 3: Reaction: The alkaloids (tryptamines) become water-soluble salts. Allow 24 hours for the initial reaction, shaking periodically to improve contact between acid and bark.
    • Step 4: Filtration: Filter the mixture through cotton or coffee filters to separate the liquid (aqueous solution) from the plant matter. Filter thinner portions first to prevent clogging. A vacuum filter is recommended.
    • Step 5: Multiple Extractions: Repeat Steps 2, 3, and 4 two more times, increasing the reaction time for subsequent extractions.
    • Base Solution and Emulsion: A 5% base solution (lye and water) is added to raise the pH to approximately 11. Stirring several hours while heating facilitates the process. The naphtha layer is then extracted .
    • Evaporation and Crystallization: The combined naphtha extracts are evaporated in a glass baking dish to obtain DMT crystals.

    Safety and Legality

    • Hazards: Muriatic acid and naphtha are hazardous materials. Methylene chloride (DCM) is mentioned as an alternative but is stated to have significant health risks (suspected carcinogen). Use appropriate safety gear (goggles, gloves).
    • DMT is illegal in the USA and is federally controlled. This information is for educational purposes only.

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    DMT Extraction Guide PDF

    Description

    Explore the fascinating world of N,N-Dimethyltryptamine (DMT), a powerful hallucinogen with unique chemical properties. This quiz covers its chemical profile, common dosages, and methods of extraction. Test your knowledge on the complexities and legality surrounding this substance.

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