Discover Diamond-Blackfan Syndrome
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Questions and Answers

What is Diamond-Blackfan syndrome?

  • A congenital form of chronic lymphocytic leukaemia
  • An autoimmune disease that causes red cell aplasia
  • A rare syndrome characterized by anaemia with normal leucocytes and platelets and grossly reduced or absent erythroblasts in the marrow (correct)
  • A type of lymphoma that affects the bone marrow

    • What is the treatment for refractory acquired red cell aplasia?

  • Immunosuppression with corticosteroids, rituximab, ciclosporin, azathioprine or ATG (correct)
  • Monoclonal antibodies such as anti-CD20
  • Iron chelation therapy
  • Regular blood transfusions

    • What is the role of iron chelation therapy in the treatment of Diamond-Blackfan syndrome?

  • It is used to prevent the development of thymomas
  • It is used to prevent the development of autoimmune diseases
  • It is the primary treatment for Diamond-Blackfan syndrome
  • It is necessary if regular blood transfusions are needed (correct)

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