Direct-Acting Cholinergic Agonists Quiz
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Direct-Acting Cholinergic Agonists Quiz

Test your knowledge of direct-acting cholinergic agonists with this quiz. Explore the pharmacokinetics, indications, and properties of choline esters such as carbachol and bethanechol. Delve into their duration of action, lipid solubility, and resistance to cholinesterase, and understand their impact on intraocular tension.

Created by
@LongLastingMeadow

Questions and Answers

What is the duration of action for Edrophonium?

5–15 min

Which drug is used for off-label use in acute colonic pseudoobstruction?

Neostigmine

Which drug is indicated for the specific antidote for poisoning with belladonna or other anticholinergics?

Physostigmine

Which drug is used for dementia of all types, from mild to moderate Alzheimer disease and in some cases of Parkinson's disease?

<p>Rivastigmine</p> Signup and view all the answers

What is the duration of action for Parathion?

<p>7–30 days</p> Signup and view all the answers

What is the main use of cholinergic agonists topically in the eye?

<p>To produce miosis (pupillary constriction) and treat glaucoma</p> Signup and view all the answers

What is the specific duration of action for Rivastigmine?

<p>30 min to 2 h or more</p> Signup and view all the answers

What is the specific duration of action for Pyridostigmine?

<p>30 min to 2 h or more</p> Signup and view all the answers

What is the specific duration of action for Physostigmine?

<p>30 min to 2 h or more</p> Signup and view all the answers

What should healthcare workers, including pharmacists and nurses, be aware of regarding cholinergic medications?

<p>Common adverse effects</p> Signup and view all the answers

What is the main use of cholinergic agonists systemically?

<p>To increase bladder tone</p> Signup and view all the answers

What is the main use of cholinesterase inhibitors like Donepezil, Galantamine, and Rivastigmine?

<p>For dementia of all types, from mild to moderate Alzheimer disease and in some cases of Parkinson's disease</p> Signup and view all the answers

Which direct-acting cholinergic agonist is resistant to cholinesterase, orally active, and has a duration of action of 30 minutes to 2 hours?

<p>Bethanechol</p> Signup and view all the answers

Which direct-acting cholinergic agonist is an alkaloid, not an ester, and has a duration of action of 30 minutes to 2 hours?

<p>Pilocarpine</p> Signup and view all the answers

Which direct-acting cholinergic agonist is a partial agonist at N receptors, has high lipid solubility, and a duration of 12–24 hours?

<p>Varenicline</p> Signup and view all the answers

Which direct-acting cholinergic agonist is off-label used to counter the effects of cycloplegics?

<p>Pilocarpine</p> Signup and view all the answers

Which direct-acting cholinergic agonist is used to increase the aqueous outflow and decrease intraocular tension in open-angle glaucoma?

<p>Pilocarpine</p> Signup and view all the answers

Which direct-acting cholinergic agonist is resistant to cholinesterase, orally active, and used for ↑ the aqueous outflow and ↓ the intraocular tension in open-angle glaucoma?

<p>Carbachol</p> Signup and view all the answers

Which direct-acting cholinergic agonist is not an ester, has good lipid solubility, and a duration of action of 30 minutes to 2 hours?

<p>Pilocarpine</p> Signup and view all the answers

Which direct-acting cholinergic agonist has a duration of action of 1–6 hours and high lipid solubility?

<p>Nicotine</p> Signup and view all the answers

Which direct-acting cholinergic agonist is indicated for xerostomia?

<p>Cevimeline</p> Signup and view all the answers

Which indirect-acting cholinergic agent increases the availability of acetylcholine at the cholinergic receptors?

<p>Carbachol</p> Signup and view all the answers

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