Questions and Answers
What is the action of Diphenoxylate + atropine (Lomotil)?
Slows peristalsis by acting on the smooth muscles in the intestine and decreases GI motility.
Which of the following are contraindications for using Diphenoxylate + atropine (Lomotil)? (Select all that apply)
Study Notes
Action
- Slows gastrointestinal (GI) peristalsis by targeting smooth muscles in the intestine.
- Reduces overall GI motility.
- Structurally similar to meperidine, which is an opioid narcotic.
- Classified as a Schedule V controlled substance, indicating low addictive potential but risk exists.
- Lacks analgesic effects, meaning it does not relieve pain.
Contraindications
- Not suitable for individuals with hypersensitivity to the drug.
- Should be avoided in patients with severe liver diseases.
- Contraindicated for those with infectious diarrhea, particularly due to pathogens like E. coli or in cases of pseudomembranous colitis.
- Use is not recommended in dehydrated individuals, as it may exacerbate their condition.
- Should be avoided in patients with angle-closure glaucoma, as it may worsen symptoms.
- Not recommended for use in children.
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Description
Test your knowledge on Diphenoxylate and Atropine (Lomotil) with these flashcards. Explore important definitions like the action and contraindications of this medication. Perfect for pharmacy students or anyone interested in pharmacology.
