15 Questions
What is the main reason for physiologic V/Q inequality?
Better perfusion of lower lung lobes due to gravity
What happens to much of the oxygen in the upper portions of the lungs due to physiologic V/Q inequality?
It never reaches the blood due to poor perfusion
How do pathological mismatches affect arterial PO2?
Decrease it
What effect does physiologic V/Q inequality have on O2 diffusion?
Decrease it
How does the process of diverting blood away from a diseased area to a healthy area help in cases of decreased air flow to a region of the lung?
It helps to maintain oxygen delivery to healthy areas
What is the initial step for oxygen to diffuse in the alveolus?
Dissolving into the watery fluid of the alveolus
Where does the oxygen primarily hydrogen bond once it enters the plasma?
With the RBC cytoplasm
Which process allows oxygen to enter the RBC cytoplasm after crossing two cell's membranes?
Diffusion
What happens to the oxygen bound to hemoglobin as the plasma empties of O2?
It dissolves into the plasma, turning hemoglobin into deoxyhemoglobin
What drives the movement of dissolved oxygen from the plasma to the peripheral tissues?
Low partial pressure of oxygen in the peripheral tissues
What condition needs to be met for the pO2 of the plasma to equal that of the periphery during the process of oxygen diffusion?
The pO2 of the plasma should equal that of the periphery
What does a left shift in the oxygen dissociation curve indicate about the binding of hemoglobin to oxygen?
Hemoglobin binds more tightly to oxygen
How does a decrease in pH affect the binding of hemoglobin to oxygen?
It increases the binding of hemoglobin to oxygen
What effect does an increase in temperature have on the binding of hemoglobin to oxygen?
It decreases the binding of hemoglobin to oxygen
How do pulmonary blood vessels respond to decreased Po2?
Vasoconstrict
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