Podcast
Questions and Answers
What is the main indication for using diltiazem?
What is the main indication for using diltiazem?
- Myocardial infarction
- Atrial fibrillation with rapid ventricular response (correct)
- Hypertension
- Sinus tachycardia
Which of the following is NOT a contraindication for diltiazem use?
Which of the following is NOT a contraindication for diltiazem use?
- Systolic blood pressure < 90mmHg
- History of Wolff-Parkinson-White (WPW) syndrome
- Sinus bradycardia (correct)
- Myocardial infarction and pulmonary congestion
How does diltiazem affect the AV node refractory periods?
How does diltiazem affect the AV node refractory periods?
- Prolongs them (correct)
- Causes arrhythmias in the AV node
- Shortens them
- Does not affect them
What is the pregnancy category of diltiazem?
What is the pregnancy category of diltiazem?
What is the class of diltiazem based on its mechanism of action?
What is the class of diltiazem based on its mechanism of action?
Which of the following adverse effects is NOT commonly associated with diltiazem use?
Which of the following adverse effects is NOT commonly associated with diltiazem use?
How does diltiazem affect serum calcium concentrations?
How does diltiazem affect serum calcium concentrations?
What is the route of excretion of diltiazem?
What is the route of excretion of diltiazem?
What are the possible additive effects when diltiazem is used concurrently with beta-blockers or digitalis?
What are the possible additive effects when diltiazem is used concurrently with beta-blockers or digitalis?
What is the main indication for using diltiazem in patients?
What is the main indication for using diltiazem in patients?
In patients with which condition should diltiazem NOT be used unless they have a functioning ventricular pacemaker?
In patients with which condition should diltiazem NOT be used unless they have a functioning ventricular pacemaker?
What is the concentration of diltiazem?
What is the concentration of diltiazem?
Which of the following is a precaution associated with diltiazem use?
Which of the following is a precaution associated with diltiazem use?
How does diltiazem affect AV node refractory periods in patients without sick sinus syndrome?
How does diltiazem affect AV node refractory periods in patients without sick sinus syndrome?
Which of the following is an adverse effect commonly associated with diltiazem use?
Which of the following is an adverse effect commonly associated with diltiazem use?
What is the route of excretion for diltiazem after metabolism?
What is the route of excretion for diltiazem after metabolism?
What effect does diltiazem have on the recovery time of the sinus node in patients without sick sinus syndrome?
What effect does diltiazem have on the recovery time of the sinus node in patients without sick sinus syndrome?
what is the initial dose when the pt is experiencing Afib with RVR or Paroxysmal SVT?
what is the initial dose when the pt is experiencing Afib with RVR or Paroxysmal SVT?
what is the 2nd dose when the pt is experiencing Afib with RVR or Paroxysmal SVT and do you need permission and how mins after the first dose?
what is the 2nd dose when the pt is experiencing Afib with RVR or Paroxysmal SVT and do you need permission and how mins after the first dose?
Study Notes
Indications and Contraindications
- Main indication for using diltiazem: AFib with RVR or Paroxysmal SVT
- Contraindication: Sick sinus syndrome without a functioning ventricular pacemaker
Effects on AV Node
- Diltiazem prolongs AV node refractory periods
- In patients without sick sinus syndrome, diltiazem prolongs AV node refractory periods
Pharmacology
- Class of diltiazem based on its mechanism of action: Calcium channel blocker
- Route of excretion: Primarily excreted in the urine and bile
- Route of excretion after metabolism: Renal elimination
Adverse Effects and Interactions
- Adverse effect commonly associated with diltiazem use: Bradycardia
- Not commonly associated with diltiazem use: Changes in serum calcium concentrations
- Additive effects when used concurrently with beta-blockers or digitalis: Increased risk of bradycardia and AV block
- Precaution associated with diltiazem use: Patients with sick sinus syndrome require a functioning ventricular pacemaker
Dosage
- Initial dose for AFib with RVR or Paroxysmal SVT: 0.25 mg/kg
- 2nd dose for AFib with RVR or Paroxysmal SVT: 0.35 mg/kg, given 15 minutes after the first dose, with permission from a physician
Pregnancy and Concentration
- Pregnancy category: C
- Concentration of diltiazem: Not specified
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Description
Test your knowledge on the indications, contraindications, and precautions associated with Diltiazem. Learn about its use in A-fib with RVR, Paroxysmal SVT, and more.
