Digoxin Toxicity
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Questions and Answers

Which of the following is true about digitalis glycosides?

  • They are no longer used in the treatment of congestive heart failure
  • They have been used in the therapy of congestive heart failure since the 18th century (correct)
  • They are derived from the foxglove plant
  • They are commonly found in Nerium oleander

    • What is the common molecular motif found in cardioactive steroids (CAS)?

  • A steroid nucleus with a saturated lactone at the C17 position and one or more glycoside residues at C3 position
  • A steroid nucleus with an unsaturated lactone at the C17 position and one or more glycoside residues at C3 position (correct)
  • A steroid nucleus with an unsaturated lactone at the C3 position and one or more glycoside residues at C17 position
  • A steroid nucleus with a saturated lactone at the C3 position and one or more glycoside residues at C17 position

    • Which plant contains cardioactive steroids (CAS) and is used by herbalists for varied disorders?

  • Digitalis purpurea
  • Nerium oleander
  • Both Digitalis purpurea and Nerium oleander (correct)
  • None of the above

    • How does digitoxin differ from digoxin?

    <p>Digitoxin differs from digoxin only by the</p> Signup and view all the answers

    What can be a lifesaving treatment for cardioactive steroid (CAS) poisoning?

    <p>Rapid recognition of the CAS toxidrome and appropriate use of digoxin-specific antibody fragments</p> Signup and view all the answers

    Which of the following statements about digitalis glycosides is NOT true?

    <p>Digitalis glycosides are toxic when exposed to herbalists.</p> Signup and view all the answers

    What is the main chemical characteristic of cardioactive steroids (CAS)?

    <p>A steroid nucleus with an unsaturated lactone at the C17 position and glycoside residues at C3 position.</p> Signup and view all the answers

    What is the plant that contains cardioactive steroids (CAS) and is used by herbalists for varied disorders?

    <p>Digitalis purpurea</p> Signup and view all the answers

    What can be a lifesaving treatment for cardioactive steroid (CAS) poisoning?

    <p>Administration of digoxin-specific antibody fragments</p> Signup and view all the answers

    How does digitoxin differ from digoxin?

    <p>Digitoxin has a different molecular structure than digoxin.</p> Signup and view all the answers

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