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Questions and Answers
What is the function of the sphincter of Oddi in the GI tract?
What is the function of the sphincter of Oddi in the GI tract?
How long does it take for significant absorption of nutrients to occur in the GI tract, based on the information provided?
How long does it take for significant absorption of nutrients to occur in the GI tract, based on the information provided?
Which part of the GI tract mixes and grinds food while it stays in it for 1-4 hours?
Which part of the GI tract mixes and grinds food while it stays in it for 1-4 hours?
What is the purpose of mastication of food in the digestive process?
What is the purpose of mastication of food in the digestive process?
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Which organ is essential for secreting digestive enzymes in the GI tract?
Which organ is essential for secreting digestive enzymes in the GI tract?
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What is the main purpose of the large intestine in the digestive process?
What is the main purpose of the large intestine in the digestive process?
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What is the main function of internal and external anal sphincters?
What is the main function of internal and external anal sphincters?
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Which stimuli induce sphincteric contraction?
Which stimuli induce sphincteric contraction?
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What innervates most muscles of mastication?
What innervates most muscles of mastication?
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What is the purpose of chewing in digestion?
What is the purpose of chewing in digestion?
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What happens when a bolus of food is in the mouth?
What happens when a bolus of food is in the mouth?
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During swallowing, what prevents food from entering the trachea?
During swallowing, what prevents food from entering the trachea?
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What initiates mixing waves in the stomach after food ingestion?
What initiates mixing waves in the stomach after food ingestion?
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What is the function of the pyloric pump in the stomach?
What is the function of the pyloric pump in the stomach?
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When do hunger contractions typically begin post-prandially?
When do hunger contractions typically begin post-prandially?
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What triggers the receptive relaxation of the stomach?
What triggers the receptive relaxation of the stomach?
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Which factor most prominently enhances the activity of the pyloric pump?
Which factor most prominently enhances the activity of the pyloric pump?
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What is one factor that inhibits gastric emptying according to the text?
What is one factor that inhibits gastric emptying according to the text?
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Which of the following can inhibit gastric emptying?
Which of the following can inhibit gastric emptying?
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What is the role of CCK in the hormonal feedback related to gastric emptying?
What is the role of CCK in the hormonal feedback related to gastric emptying?
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What is the main function of Ileocecal valve?
What is the main function of Ileocecal valve?
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Which signals greatly increase peristalsis in the small intestine after meals?
Which signals greatly increase peristalsis in the small intestine after meals?
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What types of movements help to propel chyme in the small intestine?
What types of movements help to propel chyme in the small intestine?
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How does the mucosal muscle contribute to the movement of lymph in the small intestine?
How does the mucosal muscle contribute to the movement of lymph in the small intestine?
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Which sphincter is most critical for preventing aspiration of stomach contents?
Which sphincter is most critical for preventing aspiration of stomach contents?
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What process involves signaling between the pharynx and the swallowing center in the brain stem?
What process involves signaling between the pharynx and the swallowing center in the brain stem?
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Which structure is responsible for determining if a food bolus is small enough to be swallowed?
Which structure is responsible for determining if a food bolus is small enough to be swallowed?
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What increases barrier pressure to reduce the likelihood of aspiration during medical procedures?
What increases barrier pressure to reduce the likelihood of aspiration during medical procedures?
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Which movement involves signaling between the pharynx and the brain stem?
Which movement involves signaling between the pharynx and the brain stem?
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What is the main function of the sphincter of Oddi in the GI tract?
What is the main function of the sphincter of Oddi in the GI tract?
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Which structure is responsible for determining if a food bolus is small enough to be swallowed?
Which structure is responsible for determining if a food bolus is small enough to be swallowed?
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What triggers the receptive relaxation of the stomach?
What triggers the receptive relaxation of the stomach?
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During swallowing, what prevents food from entering the trachea?
During swallowing, what prevents food from entering the trachea?
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What increases barrier pressure to reduce the likelihood of aspiration during medical procedures?
What increases barrier pressure to reduce the likelihood of aspiration during medical procedures?
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What is one factor that inhibits gastric emptying according to the provided content?
What is one factor that inhibits gastric emptying according to the provided content?
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What role do internal and external anal sphincters play in the digestive system?
What role do internal and external anal sphincters play in the digestive system?
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What stimulates mass movements in the colon after a meal?
What stimulates mass movements in the colon after a meal?
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What prevents fecal matter from dribbling through the anus?
What prevents fecal matter from dribbling through the anus?
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Which stimuli induce sphincteric contraction in the digestive system?
Which stimuli induce sphincteric contraction in the digestive system?
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What is the primary purpose of mastication in the digestive process?
What is the primary purpose of mastication in the digestive process?
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Why are newborns and individuals with transected spinal cords unable to control their external anal sphincter?
Why are newborns and individuals with transected spinal cords unable to control their external anal sphincter?
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What is the primary function of large circular contractions in the colon?
What is the primary function of large circular contractions in the colon?
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How many times is a typical food bolus chewed before passing through the esophagus without pain?
How many times is a typical food bolus chewed before passing through the esophagus without pain?
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Which reflex is essential for fortifying the parasympathetic defecation reflex?
Which reflex is essential for fortifying the parasympathetic defecation reflex?
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What triggers the stretch reflex leading to rebound contraction during chewing?
What triggers the stretch reflex leading to rebound contraction during chewing?
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Which muscle group is primarily responsible for mastication and is innervated by a motor branch of CN V?
Which muscle group is primarily responsible for mastication and is innervated by a motor branch of CN V?
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What is the main function of teniae coli in the colon?
What is the main function of teniae coli in the colon?
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What is the role of migrating motor complexes (MMCs) in the small intestine?
What is the role of migrating motor complexes (MMCs) in the small intestine?
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What is the main function of the ileocecal valve?
What is the main function of the ileocecal valve?
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How does the mucosal muscle contribute to intestinal function?
How does the mucosal muscle contribute to intestinal function?
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Which signals greatly increase peristalsis in the small intestine after meals?
Which signals greatly increase peristalsis in the small intestine after meals?
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What factor primarily affects gastric emptying based on the information provided?
What factor primarily affects gastric emptying based on the information provided?
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Which type of movements help propel chyme in the small intestine?
Which type of movements help propel chyme in the small intestine?
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What is the primary action of the soft palate during the pharyngeal stage of deglutition?
What is the primary action of the soft palate during the pharyngeal stage of deglutition?
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How does the cricopharyngeus muscle behave during the pharyngeal stage of deglutition?
How does the cricopharyngeus muscle behave during the pharyngeal stage of deglutition?
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What is the main function of the upper esophageal sphincter (UES) during deglutition?
What is the main function of the upper esophageal sphincter (UES) during deglutition?
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Which structure plays a significant role in preventing regurgitation and aspiration of gastric contents?
Which structure plays a significant role in preventing regurgitation and aspiration of gastric contents?
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How is the barrier pressure calculated in the context of gastroesophageal reflux prevention?
How is the barrier pressure calculated in the context of gastroesophageal reflux prevention?
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What effect does pregnancy have on the lower esophageal sphincter (LES)?
What effect does pregnancy have on the lower esophageal sphincter (LES)?
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Which condition is characterized by the failure of smooth muscle motility and relaxation of the lower esophageal sphincter (LES)?
Which condition is characterized by the failure of smooth muscle motility and relaxation of the lower esophageal sphincter (LES)?
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'Barrett's esophagitis' is associated with which transformation in the lower esophagus?
'Barrett's esophagitis' is associated with which transformation in the lower esophagus?
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'Carcinoma of upper esophagus' is most commonly related to which lifestyle factor?
'Carcinoma of upper esophagus' is most commonly related to which lifestyle factor?
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'Gastroesophageal Reflux Disease (GERD)' can lead to which critical issue for patients with heartburn?
'Gastroesophageal Reflux Disease (GERD)' can lead to which critical issue for patients with heartburn?
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Study Notes
Propulsion and Mixing of Food in the Alimentary Tract
Ingestion of Food
- Ingestion of food involves the breakdown of food into smaller particles and mixing with digestive enzymes and acids
- Mastication (chewing) is important for breaking down cellulose membranes, allowing digestive enzymes to act on food particles
Three Main Functions of GI Tract
- Churning: enhances digestion and absorption of nutrients
- Propulsion: caudal movement of food/waste
- Acts as a reservoir: facilitated by sphincters
Sphincters
- Specialized circular muscles that act as one-way valves
- Regulate antegrade and retrograde movement
- Proximal stimuli cause sphincteric relaxation, distal stimuli induce sphincteric contraction
- Separate low-pressure organs, maintain positive resting pressure, and coordinate with adjacent organs by intrinsic and neurohumoral stimuli
Mastication
- Most muscles of mastication are innervated by the motor branch of CN V
- Chewing is important for breaking down cellulose membranes
- A bolus of food in the mouth causes the jaw to drop, followed by a stretch reflex and rebound contraction
Deglutition
- Three stages: voluntary, pharyngeal, and esophageal
- Pharyngeal stage: involuntary, stimulated by sensitive epithelial swallowing receptor areas, and controlled by CNs IX, X, and XII
- Esophageal stage: involuntary, assisted by gravity, and controlled by primary and secondary peristalsis
Structures of the Esophagus
- Upper esophageal sphincter (UES): skeletal muscle, controlled by extrinsic cranial nerves
- Esophageal body: skeletal and smooth muscle, remains relaxed
- Lower esophageal sphincter (LES): circular smooth muscle, controlled by ENS, and tonically constricted
Motor Functions of the Stomach
- During fasting, the stomach is quiescent
- With ingestion of food, the stomach undergoes receptive relaxation, mixing waves, and gastric emptying
- Gastric emptying is regulated by signals from the duodenum and stomach
Regulation of Stomach Emptying
- Factors promoting emptying: stretching of the stomach wall, gastrin, and activity of the pyloric pump
- Factors inhibiting emptying: inhibitory signals from the duodenum, including CCK and hormonal feedback
Movements of the Small Intestine
- Segmentation movements: "chop" the chyme
- Peristalsis: propels chyme, increased after meals
- Migrating motor complexes (MMCs): interrupt at 90-minute intervals to move indigestible components
Ileocecal Valve
- Prevents backflow from the colon to the small intestine
- Forcefully closed when excess pressure builds in the cecum
- Resists reflux, and normally 1500-2000 ml of chyme empty into the cecum each day
Principle Functions of the Colon
- Absorption of water and electrolytes from chyme to form solid feces
- Storage of fecal matter until expelled
- Mixing movements: haustrations, and large circular contractions
Defecation
- Rectum is usually empty of feces
- Dribble of fecal matter through the anus is prevented by tonic constriction of the internal and external anal sphincters
- Defecation is stimulated by the gastrocolic and duodenocolic reflexes, and occurs 1-3 times a day
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Description
Test your knowledge on the sequence of events in the digestive system, from mouth to stomach to small intestine. Identify the process of mastication, secretion of gastric acid, and food movement through different organs.