Digestive System Overview and Histology

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Questions and Answers

Which part of the small intestine contains Peyer's patches as a prominent feature?

  • Colon
  • Jejunum
  • Duodenum
  • Ileum (correct)

What type of epithelium lines the mucosa of the intestinal tract for absorption?

  • Stratified squamous epithelium
  • Simple cuboidal epithelium
  • Ciliated columnar epithelium
  • Simple columnar epithelium (correct)

Which type of cell in the intestinal epithelium is primarily responsible for mucus secretion?

  • Enteroendocrine cells
  • Goblet cells (correct)
  • Enterocytes
  • Paneth cells

What is the primary function of the large intestine?

<p>Formation and expulsion of feces (C)</p> Signup and view all the answers

Which glands are present in the duodenum and secrete alkaline mucus?

<p>Brunner’s glands (A)</p> Signup and view all the answers

Which cells in the pancreas primarily secrete insulin?

<p>Beta cells (D)</p> Signup and view all the answers

What distinguishes the submucosa of the large intestine from that of the small intestine?

<p>Contains solitary lymph nodules (A)</p> Signup and view all the answers

Which component of the liver's histological structure is responsible for filtering blood?

<p>Sinusoids (D)</p> Signup and view all the answers

The inner longitudinal layer of the muscularis in the large intestine forms visible bands known as:

<p>Taeniae coli (A)</p> Signup and view all the answers

What describes the primary histological feature of the pancreas's exocrine portion?

<p>Acinar cells (C)</p> Signup and view all the answers

What type of epithelium is found in the mucosa of the esophagus?

<p>Stratified squamous non-keratinized (D)</p> Signup and view all the answers

Which layer of the digestive tract wall is primarily responsible for peristalsis?

<p>Musculosa (C)</p> Signup and view all the answers

What is the main histological feature of the gastric mucosa?

<p>Simple columnar cells secreting neutral mucus (D)</p> Signup and view all the answers

Which cells in the gastric glands secrete hydrochloric acid (HCl)?

<p>Parietal (Oxyntic) cells (B)</p> Signup and view all the answers

What function is the small intestine primarily involved in?

<p>Digestion and absorption of nutrients (D)</p> Signup and view all the answers

Which structure in the digestive system is responsible for the secretion of gastrointestinal hormones?

<p>Small intestine (C)</p> Signup and view all the answers

What distinct feature does the musculosa of the stomach have compared to the other parts of the digestive tract?

<p>Contains three muscle layers: inner oblique, middle circular, outer longitudinal (B)</p> Signup and view all the answers

Which type of connective tissue primarily makes up the submucosa layer of the digestive tract?

<p>Loose connective tissue (C)</p> Signup and view all the answers

What does the term 'adventitia' refer to in the context of the digestive tract?

<p>Outer layer of connective tissue in some organs (C)</p> Signup and view all the answers

What is the primary function of the lamina propria in the mucosa?

<p>Providing structural support and housing blood vessels and nerves (B)</p> Signup and view all the answers

What is the primary role of the muscularis layer in the digestive tract?

<p>Propulsion of gut contents (C)</p> Signup and view all the answers

Which cells in the gastric glands are responsible for secreting pepsinogen?

<p>Chief cells (D)</p> Signup and view all the answers

What unique feature distinguishes the mucosa of the stomach from that of the esophagus?

<p>Presence of simple columnar epithelium (A)</p> Signup and view all the answers

Which part of the digestive system is primarily responsible for nutrient absorption?

<p>Small intestine (A)</p> Signup and view all the answers

Which type of connective tissue is found in the submucosa of the digestive tract?

<p>Loose connective tissue (B)</p> Signup and view all the answers

What is the role of enteroendocrine cells in the gastric glands?

<p>Producing gastrointestinal hormones (A)</p> Signup and view all the answers

What distinguishes the adventitia from the serosa in the digestive tract?

<p>Presence of mesothelium (B)</p> Signup and view all the answers

Which function is NOT associated with the salivary glands?

<p>Production of bile (A)</p> Signup and view all the answers

What is the structural feature of the esophagus that aids in its function?

<p>Presence of a muscularis for peristalsis (A)</p> Signup and view all the answers

Which part of the digestive system is primarily involved in the secretion of alkaline mucus?

<p>Pancreas (B)</p> Signup and view all the answers

Which characteristic is unique to the submucosa of the duodenum compared to other sections of the small intestine?

<p>Brunner’s glands secreting alkaline mucus (A)</p> Signup and view all the answers

What is the primary role of enteroendocrine cells located in the intestinal villi?

<p>Producing hormones like serotonin and secretin (D)</p> Signup and view all the answers

Which histological feature is characteristic of the large intestine's mucosa?

<p>Crypts lined with goblet and columnar cells (D)</p> Signup and view all the answers

Which component of the liver primarily aids in metabolizing nutrients?

<p>Hepatocytes (A)</p> Signup and view all the answers

Which pancreatic cells are primarily responsible for producing glucagon?

<p>Alpha cells (A)</p> Signup and view all the answers

What is one of the main differences between the muscularis layers of the small and large intestine?

<p>Presence of taeniae coli in the large intestine (C)</p> Signup and view all the answers

What type of cells do the salivary glands primarily consist of?

<p>Mucous and serous cells (D)</p> Signup and view all the answers

What histological feature distinguishes the submucosa of the intestine?

<p>Presence of lymph nodes (A)</p> Signup and view all the answers

Which function is NOT associated with the liver?

<p>Production of digestive enzymes (D)</p> Signup and view all the answers

Which type of connective tissue is mainly found in the serosa of the digestive tract?

<p>Loose connective tissue (A)</p> Signup and view all the answers

Flashcards

What is the digestive system?

The digestive system is a long, muscular tube that begins at the mouth and ends at the anus. It's responsible for breaking down food into smaller molecules that the body can absorb and use.

What are salivary glands and what do they do?

The salivary glands produce saliva, which contains enzymes that start the digestion of carbohydrates.

What is the stomach and what does it do?

The stomach is a muscular sac that churns food and mixes it with gastric juices, which contain enzymes and acids that break down proteins.

What is the small intestine and what does it do?

The small intestine is a long, coiled tube where most of the digestion and absorption of nutrients takes place.

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What is the large intestine and what does it do?

The large intestine is a shorter, wider tube where water is absorbed from the remaining food matter and waste is formed.

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What is the mucosa and what does it do?

The mucosa is the innermost layer of the digestive tract wall, containing epithelial cells for protection, secretion, and absorption.

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What is the submucosa and what does it do?

The submucosa is a layer of loose connective tissue beneath the mucosa, containing glands and blood vessels.

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What is the muscularis and what does it do?

The muscularis is a layer of smooth muscle that helps move food through the digestive tract via peristalsis.

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What is the serosa and what does it do?

The serosa is the outermost layer of the digestive tract wall, protecting and lubricating the organs.

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What is the esophagus and what does it do?

The esophagus is a muscular tube that connects the pharynx to the stomach, allowing food to pass from the mouth to the stomach.

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Duodenum

The first part of the small intestine, responsible for receiving chyme from the stomach and mixing it with pancreatic juice and bile.

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Jejunum

The middle part of the small intestine where the majority of nutrient absorption occurs.

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Ileum

The last part of the small intestine, responsible for nutrient absorption and absorbing bile salts.

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Intestinal Villi

Finger-like projections in the small intestine that increase surface area for nutrient absorption.

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Peristalsis

The process of moving food through the digestive tract by muscle contractions.

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Amylase

The main digestive enzyme secreted by the pancreas, responsible for breaking down starches into sugars.

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Insulin

The primary hormone secreted by the pancreas that lowers blood glucose levels by stimulating glucose uptake by cells.

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Glucagon

The primary hormone secreted by the pancreas that raises blood glucose levels by stimulating glycogen breakdown in the liver.

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Liver

The largest internal organ, responsible for producing bile and performing many vital metabolic functions.

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Hepatocytes

Star-shaped liver cells that line the sinusoids and perform numerous metabolic functions.

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What is the muscularis layer and what does it do?

The muscularis layer of the digestive tract has inner circular and outer longitudinal muscle layers responsible for peristalsis.

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What is the mucosa layer and what is its purpose?

The mucosa, the innermost layer, has different types of epithelial cells for protection, secretion, and absorption. This is where most of the digestive action happens.

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What is the submucosa layer and what are its functions?

The submucosa layer contains glands and blood vessels. Important for transporting nutrients and creating supportive structures.

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What is the serosa layer and what is its function?

The serosa is the outermost layer, protecting and lubricating the digestive organs. It's like the outer lining of the tube.

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What is the stomach and what is its function?

The stomach churns food and mixes it with gastric juices containing enzymes and acids for protein breakdown.

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What is the small intestine and what happens there?

The small intestine, a long tube, is where most of the digestion and absorption of nutrients happen. This is the primary site of nutrient absorption.

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What is the large intestine and what happens there?

The large intestine, a shorter, wider tube, absorbs water from remaining food and forms waste. This is where waste is formed and compacted.

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What does the pancreas do?

The pancreas secretes digestive enzymes like amylase and lipase into the small intestine to break down carbohydrates and fats. It also produces insulin and glucagon, hormones that regulate blood sugar.

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Liver Sinusoids

Blood spaces lined with Kupffer cells (liver macrophages) in the liver, serving as filters for blood.

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Pancreas: Exocrine and Endocrine Functions

The pancreas is an organ with both exocrine and endocrine functions. The exocrine part produces digestive enzymes, while the endocrine part secretes hormones like insulin and glucagon.

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Liver: Bile Production

The liver is responsible for producing bile, an essential substance for lipid digestion.

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Study Notes

Digestive System Overview

  • The digestive system is a muscular tube extending from the mouth to the anus.
  • Associated glands include the salivary glands, pancreas, liver, and gallbladder.
  • The tract's main components are the oral cavity, oropharynx, esophagus, stomach, small intestine, large intestine, rectum, and anal canal.

Histological Structure of the Digestive Tract

  • The digestive tract wall has four layers: mucosa, submucosa, muscularis, and serosa/adventitia.
  • Mucosa: Contains epithelium (protective, secretory, absorptive), lamina propria, and muscularis mucosa. Epithelial types vary by location (e.g., stratified squamous in esophagus, simple columnar in stomach).
  • Submucosa: Loose connective tissue, containing glands (e.g., esophageal and Brunner's in the duodenum).
  • Muscularis: Inner circular and outer longitudinal smooth muscle layers causing movement (peristalsis).
  • Serosa/Adventitia: Loose connective tissue with/without a mesothelium outer layer.

Organ-Specific Features & Histology

Esophagus

  • A long, muscular tube connecting the pharynx to the stomach.
  • Histology: stratified squamous non-keratinized epithelium in the mucosa, loose connective tissue in the submucosa, two muscle layers (circular, longitudinal), and an adventitia (connective tissue). Esophageal glands are present in the submucosa.

Stomach

  • Sections include cardiac, fundus/body, and pylorus.
  • Histology: Simple columnar epithelial cells secrete mucus to protect against acid. A three layered muscle layer (inner oblique, middle circular, outer longitudinal) is present. Gastric glands contain mucous neck cells, parietal cells (HCl), chief cells (pepsinogen), enteroendocrine cells (hormones), and stem cells.

Small Intestine

  • Functions: Digestion completion, nutrient absorption, hormone secretion.
  • Divisions: duodenum, jejunum, ileum
  • Histology features simple columnar epithelium with villi (absorption) and goblet cells (mucus). Contains Brunner's glands (duodenum/alkaline mucus) and Peyer's patches (ileum/lymphoid tissue) in the submucosa. Has inner and outer smooth muscle layers. Intestinal villi are present, and the core contains blood vessels, capillaries, and lymphatics. Enterocytes (absorptive cells with microvilli) and goblet cells are also present.

Large Intestine

  • Functions: Water and electrolyte absorption, feces formation and expulsion
  • Histology: No villi, contains crypts lined with goblet and columnar cells. Submucosa contains loose connective tissue. The longitudinal layer forms 3 bands called taeniae coli. Fatty appendages (appendices epiploicae) are found in the serosa.

Glands Associated with Digestive Tract

Salivary Glands
  • Types: parotid, submandibular, sublingual
  • Functions: Saliva aids in lubrication, digestion, and immune protection.
Pancreas
  • Exocrine function: secretes digestive enzymes (amylase, lipase).
  • Endocrine function: secretes hormones (insulin, glucagon, somatostatin).
  • Histology: exocrine acini and endocrine islets of Langerhans (beta -insulin, alpha- glucagon, delta- somatostatin).
Liver
  • Functions: Bile secretion (exocrine) and nutrient metabolism (endocrine).
  • Blood supply: two sources portal vein (mostly, nutrient rich) and hepatic artery (oxygen rich). The portal vein supplies approximately 75% of the blood.
  • Histology has hepatocytes (radiating around central vein), sinusoids with Kupffer cells (macrophages), and portal tracts (part of vein, artery and bile duct).

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