Digestive System Anatomy and Functions Quiz

The primary function of the small intestine is the absorption of nutrients from digested food.

The colon's role in the digestive system includes absorbing water and electrolytes from digested material, forming and storing feces, and facilitating the elimination of waste through the anus.

Challenges associated with oral drug administration include potential destruction or inactivation of drugs in the stomach, irritation of the oral mucosa, unpleasant taste, variability in absorption, and the influence of metabolic enzymes and efflux transporters.

<p>Factors that may affect drug absorption in the colon include slow transit time, varying pH levels, the presence of microflora, and the activity of metabolic enzymes and efflux transporters.</p> Signup and view all the answers

<p>The colon contributes to the overall absorption of nutrients and drugs by absorbing water, electrolytes, and certain drugs, and by providing a site for the action of colonic microflora and certain enzymes.</p> Signup and view all the answers

<p>Challenges associated with oral drug administration include potential destruction or inactivation of drugs in the stomach, irritation of the oral mucosa, unpleasant taste, difficulties in dosage flexibility, and the need for relatively high doses due to low absorption.</p> Signup and view all the answers

<p>The colon contributes to drug absorption through its relatively slow transit time, which allows for prolonged exposure of drugs to the colonic membrane, and the presence of microflora that may affect drug metabolism and availability.</p> Signup and view all the answers

<p>Drug absorption in the colon is characterized by relatively low pH variations, stability of drugs at pH 6.6, and the potential influence of efflux transporters and proteolytic enzymes on drug levels.</p> Signup and view all the answers

<p>The colon's anatomy, including its large surface area and the presence of electrolytes, contributes to the absorption of drugs.</p> Signup and view all the answers