Differential Diagnoses for T-cell Lymphomas Quiz
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Questions and Answers

What is the most common type of cutaneous T cell lymphoma?

  • Clonal CD4+ T cells (correct)
  • CD8+ T cells
  • CD45+ cells
  • TTF1+ cells

Which type of tumor cells are found in Sézary syndrome?

  • Hodgkin lymphoma cells
  • Neoplastic T cells with cerebriform nuclei (correct)
  • Monotonous round tumor cells
  • Metastatic small cell carcinoma

Which stage of Mycosis Fungoides is characterized by thickened plaques that may resemble psoriasis?

  • Plaque (correct)
  • Sézary syndrome
  • Tumoral
  • Patch

Which microscopic feature is associated with the patch stage of Mycosis Fungoides?

<p>Clustered in epidermis (A)</p> Signup and view all the answers

What is the differential diagnosis for metastatic small cell carcinoma if it is from the lung?

<p>TTF1+ (A)</p> Signup and view all the answers

What characterizes Sézary syndrome?

<p>Erythroderma and neoplastic T cells w cerebriform nuclei (B)</p> Signup and view all the answers

Which tumor cells are positive for CD4 and negative for CD8 in Mycosis Fungoides?

<p>Neoplastic T cells w cerebriform nuclei (B)</p> Signup and view all the answers

What are the microscopic features of actinic keratosis?

<p>Parakeratosis and dermal elastosis (B)</p> Signup and view all the answers

Which type of UV radiation is absorbed by the epidermis and considered the most carcinogenic?

<p>UV-B (D)</p> Signup and view all the answers

What gene mutation is associated with the pathogenesis of basal cell carcinoma?

<p>p53 (B)</p> Signup and view all the answers

What is the most common type of basal cell carcinoma to be seen in sun-exposed skin?

<p>Superficial basal cell carcinoma (B)</p> Signup and view all the answers

Which treatment for basal cell carcinoma is not always needed?

<p>Chemotherapy (C)</p> Signup and view all the answers

What are hedgehog proteins involved in?

<p>Cell proliferation and differentiation (B)</p> Signup and view all the answers

What are the risk factors for basal cell carcinoma?

<p>UV exposure, gene mutations, arsenic exposure (B)</p> Signup and view all the answers

What causes the small rough spots seen in actinic keratosis?

<p>Cutaneous horn (B)</p> Signup and view all the answers

Which of the following tumors is associated with nevoid basal cell carcinoma syndrome?

<p>Basal cell carcinomas in the skin (C)</p> Signup and view all the answers

What is a common risk factor for squamous cell carcinoma (SCC) mentioned in the text?

<p>HPV 5/8 infection (C)</p> Signup and view all the answers

Which of the following tumor types express neuroendocrine markers such as CD56 and chromogranin?

<p>Merkel cell carcinoma (A)</p> Signup and view all the answers

Which type of squamous cell carcinoma is characterized by loss of intercellular connection (Acantholysis)?

<p>Conventional type (B)</p> Signup and view all the answers

Which tumor type is graded according to the degree of differentiation and may present with ulceration and hemorrhage?

<p>Squamous cell carcinomas (B)</p> Signup and view all the answers

What is a microscopic feature of Merkel cell carcinoma?

<p>Monotonous round tumor cells (A)</p> Signup and view all the answers

Which of the following tumors is NOT associated with nevoid basal cell carcinoma syndrome?

<p>Pancreatic cancer (C)</p> Signup and view all the answers

Which infection is often a risk factor for squamous cell carcinoma?

<p>Human papillomavirus (HPV) (D)</p> Signup and view all the answers
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