15 Questions
Which type of liver tests represent liver associated enzymes but not liver function?
Liver function tests
Which liver enzyme abnormalities reflect 'injury' to hepatocytes or bile duct cells?
Aminotransferases
What is the main cause of elevations in serum alkaline phosphatase?
Diseases of the liver
Which enzyme is reserved for confirmatory testing for cholestasis?
Serum GGT
What does serum 5’ nucleotidase indicate when elevated?
Cholestasis
What type of liver injury tests reflect both hepatocellular and cholestatic abnormalities?
Aminotransferases
What is the potential cause of elevated AST/ALT levels in acute liver injuries?
All of the above
Which biomarker is highly sensitive in detecting chronic drinking and can be detected in the blood for 2-4 weeks after drinking has stopped?
Phosphatidylethanol
Which liver disease is associated with metabolic syndrome?
Non-alcoholic fatty liver disease (NAFLD)
Which test is elevated with chronic alcohol drinking and must be used with GGT and Alkaline Phosphatase?
Carbohydrate-deficient transferrin (CDT)
What is the priority of evaluation when assessing liver damage?
Presence of alarm symptoms
Which condition may not show elevated ALT/AST levels due to little new cell injury occurring in the liver?
Cirrhosis
Which imaging technique may be ordered to assess liver damage?
Ultrasound
What could be a potential cause of acute liver failure?
Viral hepatitis A, B, C
Which condition takes about 20+ years to develop into cirrhosis or chronic liver failure?
Non-alcoholic fatty liver disease (NAFLD)
This quiz covers the recognition and definition of the difference between liver injury tests and liver function tests. It also describes the characteristics of hepatocellular, cholestatic, and mixed patterns of liver injury.
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